Results 11 to 20 of about 18,577 (218)

Searching for Drug Synergy Against Cancer Through Polyamine Metabolism Impairment: Insight Into the Metabolic Effect of Indomethacin on Lung Cancer Cells

open access: yesFrontiers in Pharmacology, 2020
Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation ...
Freddy López-Contreras   +9 more
doaj   +1 more source

Responses of Polyamine-Metabolic Genes to Polyamines and Plant Stress Hormones in Arabidopsis Seedlings

open access: yesCells, 2021
In plants, many of the enzymes in polyamine metabolism are encoded by multiple genes, whose expressions are differentially regulated under different physiological conditions.
Yusaku Yariuchi   +3 more
doaj   +1 more source

Glutamate, Ornithine, Arginine, Proline, and Polyamine Metabolic Interactions: The Pathway Is Regulated at the Post-Transcriptional Level [PDF]

open access: yes, 2016
The metabolism of glutamate into ornithine, arginine, proline, and polyamines is a major network of nitrogen-metabolizing pathways in plants, which also produces intermediates like nitric oxide, and γ-aminobutyric acid (GABA) that play critical roles in ...
Boubker eBarchi   +7 more
core   +8 more sources

Inhibiting Copper Amine Oxidase Using L-Aminoguanidine Induces Cultivar and Age-Dependent Alterations of Polyamine Catabolism in Tomato Seedlings

open access: yesAgriculture, 2022
Many effects of polyamines (PAs) are well known in plant developmental processes; however, the significance of their catabolism is not well understood. Copper amine oxidase (CuAO) is involved in the degradation of diamine putrescine (Put).
Ágnes Szepesi   +4 more
doaj   +1 more source

The immunological effects of the polyamine oxidase enzyme partially cleared from the cerebrospinal fluid against secondary secondary cystitis in white mice. Coagulation factor and delayed hypersensitivity [PDF]

open access: yesمجلة التربية والعلم, 2007
The study included immune response to infection with secondary hydatid disease in BALB/c mice activated by partially purified cerebrospinal fluid-polyamine oxidase (CSF-PAO) with spermine and infected with protoscoleces of Echinococcus granulosus.
Khawla Al-Flaeh, Asmaa Ali, Wathba Ali
doaj   +1 more source

Involvement of Polyamine Oxidase in Wound Healing [PDF]

open access: yesPlant Physiology, 2007
AbstractHydrogen peroxide (H2O2) is involved in plant defense responses that follow mechanical damage, such as those that occur during herbivore or insect attacks, as well as pathogen attack. H2O2 accumulation is induced during wound healing processes as well as by treatment with the wound signal jasmonic acid.
Angelini, R.   +6 more
openaire   +3 more sources

Semicarbazide diminishes the signs of bleomycin-induced pulmonary fibrosis in rats [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2021
The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation.
O. O. Hudkova   +5 more
doaj   +1 more source

Polyamine Oxidase from Water Hyacinth [PDF]

open access: yesPlant Physiology, 1987
Polyamine oxidase was purified to homogeneity from leaves of water hyacinth by the criterion of sodium dodecyl sulfate gel electrophoresis (SDS disc PAGE). The enzyme showed a high specificity for spermidine and spermine (K(m) values 28 micromolar and 20 micromolar, respectively).
H, Yanagisawa   +4 more
openaire   +2 more sources

The silicon trypanosome [PDF]

open access: yes, 2010
African trypanosomes have emerged as promising unicellular model organisms for the next generation of systems biology. They offer unique advantages, due to their relative simplicity, the availability of all standard genomics techniques and a long history
BARBARA M. BAKKER   +10 more
core   +4 more sources

Inhibition of acetylpolyamine and spermine oxidases by the polyamine analogue chlorhexidine [PDF]

open access: yes, 2012
""Acetylpolyamine and spermine oxidases are involved in the catabolism of polyamines. The discovery of selective. inhibitors of these enzymes represents an important tool for the development of novel anti-neoplastic drugs. Here, a.
Angelucci, E   +5 more
core   +1 more source

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