Results 141 to 150 of about 51,057 (260)

Comparison of Early Postoperative Diaphragm Muscle Function after Lobectomy via VATS and Open Thoracotomy: A Sonographic Study

Life
Although a growing body of evidence emphasizes the superiority of VATS over conventional thoracotomy, little is still known about early postoperative diaphragm muscle function after lobectomy via these two approaches.
Janusz Kocjan, Mateusz Rydel, Damian Czyżewski, Mariusz Adamek   +3 more
doaj   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Diaphragm Muscle Atrophy Contributes to Low Physical Capacity in COVID-19 Survivors

Life
Fatigue and dyspnea are the most commonly reported long-term complaints in individuals previously infected with SARS-CoV-2. This study aimed to comprehensively evaluate diaphragm muscle function in post-COVID-19 patients and investigate whether potential
Janusz Kocjan, Mateusz Rydel, Jan Szczegielniak, Katarzyna Bogacz, Mariusz Adamek   +4 more
doaj   +1 more source

Combined multi‐metric assessment of diaphragm contractile function in healthy humans: Feasibility, validity and reliability

Experimental Physiology, EarlyView.
Abstract The combined use of subcostal ultrasonography and respiratory manometry represents a novel, integrative method for quantifying diaphragm contractile function (force, velocity and power). We evaluated the technical feasibility, construct validity and within‐day test–retest reliability of this method during non‐volitional, volitional and ...
Camilla R. Illidi, Lee M. Romer
wiley   +1 more source

Congenital CMV associated with diaphragm dysfunction: a rare cause of tachypnoea. [PDF]

BMJ Case Rep, 2023
Carter R, Yakir M, Ryu J, Weiss K.
europepmc   +1 more source

Neuromuscular and neuromechanical assessments of respiratory performance in the mdx mouse model of Duchenne muscular dystrophy across the natural history of disease

Experimental Physiology, EarlyView.
Abstract Duchenne muscular dystrophy (DMD) is a severe life‐limiting X‐linked neuromuscular disorder characterised by progressive skeletal muscle degeneration and respiratory failure. The mdx mouse, lacking dystrophin, is the most widely used preclinical model of DMD, yet the trajectory of respiratory dysfunction in this model remains incompletely ...
Michael N. Maxwell, Christopher G. Wilson, Mai K. Elmallah, Federica Trucco, Ken D. O'Halloran   +4 more
wiley   +1 more source

Thrombospondin-1 promotes fibro-adipogenic stromal expansion and contractile dysfunction of the diaphragm in obesity

JCI Insight
Pulmonary disorders affect 40%–80% of individuals with obesity. Respiratory muscle dysfunction is linked to these conditions; however, its pathophysiology remains largely undefined.
Eric D. Buras, Moon-Sook Woo, Romil Kaul Verma, Sri Harshita Kondisetti, Carol S. Davis, Dennis R. Claflin, Kimber Converso-Baran, Daniel E. Michele, Susan V. Brooks, Tae-Hwa Chun   +9 more
doaj   +1 more source

Association between diaphragm excursion and whole-body muscle mass in older adults: an observational study

Scientific Reports
Symptoms of diaphragm dysfunction, such as exertional dyspnea and decreased exercise tolerance, share similarities with the symptoms of skeletal muscle mass reduction caused by conditions like sarcopenia.
Shuji Ouchi, Toru Yamada, Takahiro Shinohara, Suguru Mabuchi, Kazuharu Nakagawa, Kanako Yoshimi, Ayane Horike, Tatsuya Mayama, Kenji Toyoshima, Yoshiaki Tamura, Atsushi Araki, Ryoichi Hanazawa, Akihiro Hirakawa, Hiroyuki Ichige, Takeshi Ishida, Takuma Kimura, Haruka Tohara, Masayoshi Hashimoto   +17 more
doaj   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Cellular senescence contributes to mechanical ventilation-induced diaphragm dysfunction by upregulating p53 signalling pathways. [PDF]

BMC Pulm Med, 2023
Shen W, Jiang Y, Xu Y, Qian X, Jia J, Ding Y, He Y, Pan Q, Zhuang J, Ge H, Xu P.   +10 more
europepmc   +1 more source