Results 21 to 30 of about 28,431 (153)

Altered expression of microRNAs in the rat diaphragm in a model of ventilator-induced diaphragm dysfunction after controlled mechanical ventilation

BMC Genomics, 2021
Background Ventilator-induced diaphragm dysfunction (VIDD) is a common complication of life support by mechanical ventilation observed in critical patients in clinical practice and may predispose patients to severe complications such as ventilator ...
Pengcheng Wang, Xianlong Zhou, Gang Li, Haoli Ma, Ruining Liu, Yan Zhao   +5 more
doaj   +1 more source

Assessment of excursion and thickness of diaphragm by ultrasound during acute exacerbation of chronic obstructive pulmonary disease and correlation with severity of airway obstruction

Journal of Association of Pulmonologist of Tamil Nadu, 2023
Background: Diaphragm dysfunction in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) leads to increased morbidity and mortality. Early diagnosis of diaphragm dysfunction and aggressive management to improve the diaphragm function and
M Vishnu Sharma, S R Chandrik Babu
doaj   +1 more source

Diaphragm atrophy and contractile dysfunction in a murine model of pulmonary hypertension. [PDF]

PLoS ONE, 2013
Pulmonary hypertension (PH) causes loss of body weight and inspiratory (diaphragm) muscle dysfunction. A model of PH induced by drug (monocrotaline, MCT) has been extensively used in mice to examine the etiology of PH.
Bumsoo Ahn, Hyacinth M Empinado, Monsour Al-Rajhi, Andrew R Judge, Leonardo F Ferreira   +4 more
doaj   +1 more source

Ultrasonographic assessment of skeletal muscle mass and diaphragm function in patients with chronic obstructive pulmonary disease: A case–control study

Lung India, 2020
Background: Although muscle dysfunction is a major contributor to morbidity in chronic obstructive pulmonary disease (COPD), assessment of skeletal muscle, and diaphragm function is not routinely performed in COPD patients.Objectives: (1) The aim is to ...
Priya Ramachandran, Uma Devaraj, Bhavna Patrick, Deepali Saxena, Kavitha Venkatnarayan, Varghese Louis, Uma Maheswari Krishnaswamy, George A D'souza   +7 more
doaj   +1 more source

The Perception of the Diaphragm with Ultrasound: Always There Yet Overlooked?

Life
Diaphragm ultrasound makes it possible to diagnose diaphragmatic atrophy and dysfunction. Important indications include unclear dyspnea; diaphragmatic elevation; assessment of diaphragm dysfunction in pulmonary, neuromuscular and neurovascular diseases ...
Kathleen Möller, Max Saborio, Heike Gottschall, Michael Blaivas, Adrian C. Borges, Susanne Morf, Burkhard Möller, Christoph F. Dietrich   +7 more
doaj   +1 more source

Ventilator-Induced Diaphragm Dysfunction (Review)

Общая реаниматология, 2018
Mechanical ventilation is associated with a number of complications that increase the cost of treatment and the hospital mortality rate. In 2004, the term «ventilator-induced diaphragm dysfunction» (VIDD) was proposed to explain one of the reasons for ...
M. A. Babaev, D. B. Bykov, Т. M. Birg, M. А. Vyzhigina, A. A. Eremenko   +4 more
doaj   +1 more source

Diaphragmatic Dynamics and Thickness Parameters Assessed by Ultrasonography Predict Extubation Success in Critically Ill Patients

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2023
INTRODUCTION A frequent cause of weaning and extubation failure in critically ill mechanically ventilated patients is diaphragm muscle dysfunction. Ultrasound (US) evaluation of the diaphragm yields important data regarding its thickness (diaphragm ...
Marlon Adrián Laguado-Nieto, Sandra Liliana Roberto-Avilán, Francisco Naranjo-Junoy, Héctor Julio Meléndez-Flórez, Ivan David Lozada-Martinez, Gonzalo Andrés Domínguez-Alvarado, Víctor Alfonso Campos-Castillo, Sergio Uriel Ríos-Orozco, Alexis Rafael Narváez-Rojas   +8 more
doaj   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Diaphragmatic thickening fraction as a predictor for intubation in patients with COVID-19

Respiratory Medicine Case Reports, 2022
The diaphragm is the primary respiratory muscle, and its dysfunction predisposes patients to respiratory failure. Diaphragm function can be assessed by ultrasound measurement - Diaphragmatic Thickening Fraction (DTF).
Manuel Hache-Marliere, Hyomin Lim, Hassan Patail   +2 more
doaj   +1 more source

A Periosteum‐Inspired Janus Piezoelectric Scaffold Using Bioenergetic‐Driven H‐Type Vascularization for Diabetic Bone Regeneration

Advanced Science, EarlyView.
A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley   +1 more source