Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia [PDF]
BACKGROUND: Evidence from cachectic cancer patients and animal models of cancer cachexia supports the involvement of Forkhead box O (FoxO) transcription factors in driving cancer-induced skeletal muscle wasting. However, the genome-wide gene networks and
Beharry, Adam W. +6 more
core +1 more source
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi +15 more
wiley +1 more source
Prolonged mechanical ventilation worsens sepsis-induced diaphragmatic dysfunction in the rat.
BackgroundShort-term mechanical ventilation (MV) protects against sepsis-induced diaphragmatic dysfunction. Prolonged MV induces diaphragmatic dysfunction in non-septic animals, but few reports describe the effects of prolonged MV in sepsis.
Matthieu Le Dinh +8 more
doaj +1 more source
Characterisation of hemidiaphragm dysfunction using dynamic chest radiography: a pilot study
Objectives Dynamic chest radiography (DCR) is a novel real-time digital fluoroscopic imaging system that produces clear, wide field-of-view diagnostic images of the thorax and diaphragm in motion, alongside novel metrics on moving structures within the ...
Thomas Simon FitzMaurice +3 more
doaj +1 more source
Restoring Functional Status: A Long-Term Case Report of Severe Lung and Ventilatory Muscle Pump Dysfunction Involving Recurrent Bacterial Pneumonias [PDF]
Background and Purpose: Prolonged mechanical ventilation contributes to immobility and deconditioning making efforts to safely discontinue ventilator support desirable. This case report documents how implementing physical therapy treatment interventions,
Laatsch-Lybeck, Linda Jean +2 more
core +2 more sources
The Correlation Between Body Fat Percentage and Peak Expiratory Flow in Children Aged 10-12 Years at SD Negeri 8 Dauh Puri [PDF]
Background: The accumulation of fat decreases lung function. Peak expiratory flow is an indicator for assessing pulmonary function and can be used to identify the narrowing or obstruction of the airway. This study aimed to examine the correlation between
Indahswari, N. W. (Ni) +3 more
core +2 more sources
Exploring the Clinical Potential of Dynamic Digital Radiography: A Narrative Review
Dynamic Digital Radiography (DDR) is a promising X‐ray technology that captures rapid image sequences, enabling the visualisation of moving anatomical structures for various clinical applications, including pulmonary, cardiac and orthopaedic assessments.
Connor W. Braniff, Mohamed K. Badawy
wiley +1 more source
Diaphragm paralysis has been observed following cervical spinal cord and diaphragm injuries. Patients with diaphragm paralysis require plication of the diaphragm if significant pulmonary dysfunction occurs.
Pedram Talebian +3 more
doaj +1 more source
Mechanical ventilation causes diaphragm dysfunction in newborn lambs [PDF]
Diaphragm weakness occurs rapidly in adult animals treated with mechanical ventilation (MV), but the effects of MV on the neonatal diaphragm have not been determined. Furthermore, it is unknown whether co-existent lung disease exacerbates ventilator-induced diaphragmatic dysfunction (VIDD).
Feng Liang +10 more
openaire +3 more sources
Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease. [PDF]
Cardiovascular dysautonomia as well as the deterioration of circadian rhythms are among the earliest detectable pathophysiological changes in individuals with Huntington's disease (HD). Preclinical research requires mouse models that recapitulate disease
Colwell, Christopher S +7 more
core +1 more source

