Results 41 to 50 of about 31,184,994 (256)

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Bovine Viral Diarrhea Virus Testing Options

, 2003
A review of bovine viral diarrhea virus (BVDV) dynamics is followed by a review of test efficiency measures. BVDV diagnostic challeneges are then discussed with attention to its pathogenesis during pregnancy and fetal effects.
Slenning, Barrett D.
core   +1 more source

High Prevalence of Bovine Viral Diarrhea Virus-1 in Sheep Abortion Samples with Pestivirus Infection in Turkey

, 2018
Received: Revised: Accepted: Published online: July 05, 2017 September 18, 2017 September 19, 2017 November 21, 2017 The aim of this study is the detection of prevalence of bovine viral diarrhea virus-1 (BVDV-1) in sheep abortion samples in Turkey.
H. Bulut, İ. Sözdutmaz, Zuleyha Pestil, Hasan Abayli, A. Sait, A. Çevik   +5 more
semanticscholar   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Bovine Viral Diarrhea Virus Infections in Commingled and Transported Calves: Fall 2000 Study and Summary of a Three-year Study

, 2001
Bovine viral diarrhea virus (BVDV) infections, in both persistently infected (PI) and/or acutely infected calves, were investigated in commingled and transported calves. Other viral infections such as bovine herpesvirus-1 (BHV), parainfluenza-3 virus (Pl-
Confer, A. W., Loan, R. W., Burge, L. J., Duff, G. C., Saliki, J. T., Step, D. L., Fulton, R. W., Purdy, C. W., Briggs, R. E., Ridpath, J. F.   +9 more
core   +1 more source

Molecular characterization of ten viral pathogens causing calf diarrhea in Hanwoo (Bos Taurus coreanae) by next generation sequencing

BMC Veterinary Research
Background Calf diarrhea remains a significant concern in the global cattle industry, leading to considerable economic losses. Infectious pathogens are among the primary causes of this disease.
Jeong-Byoung Chae, Won Gyeong Kim, Shinae Song, Joon-Seok Chae   +3 more
doaj   +1 more source

Some viral and bacterial respiratory tract infections of dairy cattle during the summer season [PDF]

Acta Veterinaria, 2013
In this research, dairy cattle with respiratory system problems that were brought to a private slaughterhouse in Burdur province were investigated for viral and bacterial infections present in the summer season.
Kale M., Ozturk Dýlek, Hasircioglu Sýbel, Pehlivanoglu F., Turutoglu Hulya   +4 more
doaj   +1 more source

Identification and Genetic Characterization of Viral Pathogens in Ruminant Gestation Abnormalities, Israel, 2015–2019

Viruses, 2021
Infectious agents including viruses are important abortifacients and can cause fetal abnormalities in livestock animals. Here, samples that had been collected in Israel from aborted or malformed ruminant fetuses between 2015 and 2019 were investigated ...
Natalia Golender, Velizar Bumbarov, Anita Kovtunenko, Dan David, Marisol Guini-Rubinstein, Asaf Sol, Martin Beer, Avi Eldar, Kerstin Wernike   +8 more
doaj   +1 more source

Complete Genome Sequencing of Bovine Viral Diarrhea Virus 1, Subgenotypes 1n and 1o

Genome Announcements, 2016
To gain further insight into the genomic features of bovine viral diarrhea virus 1 (BVDV-1) subgenotypes, we sequenced the complete genome of BVDV-1n Shitara/02/06 and BVDV-1o IS26NCP/01. The complete genome of Shitara/02/06 and IS26NCP/01 shared 77.7 to
Asuka Sato, Kentaro Tateishi, M. Shinohara, Y. Naoi, Mai Shiokawa, H. Aoki, K. Ohmori, T. Mizutani, J. Shirai, M. Nagai   +9 more
semanticscholar   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source