Results 71 to 80 of about 2,615 (176)

Exploring the Cancer Therapeutic Potential of Traditional Medicinal Plants by Modulating the Apoptotic Pathway

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Cancer is a versatile disease with a high rate of relapse and mortality. Despite the presence of various treatment modalities, there is a serious need for the development of its management. Phytochemicals, which are abundant in nature, can be turned into novel medications for these types of diseases by optimizing their functions and ...
Mithila Kulkarni, Mohammad Amjad Hussain, Reginald Samson Valdar, Shreya Hebbar, Suparna Laha, Poorani Gurumallesh Prabu   +5 more
wiley   +1 more source

LC-ESI/LTQOrbitrap/MS/MS Analysis Reveals Diarylheptanoids and Flavonol -glycosides in Fresh and Roasted Hazelnut ( cultivar “Tonda di Giffoni”)

Natural Product Communications, 2018
Hazelnut represents one of the most consumed food, containing a large range of bioactive and health-promoting compounds. Investigation of the fatty component of C.
Antonietta Cerulli, Assunta Napolitano, Milena Masullo, Cosimo Pizza, Sonia Piacente   +4 more
doaj   +1 more source

Integrated chloroplast genomics and whole‐genome resequencing reveals demographic history and selection signatures of black walnuts

The Plant Genome, Volume 18, Issue 4, December 2025.
Abstract Elucidating the impacts of demographic history and genomic selection on species evolution is a central topic in phylogeography and evolutionary biology. Black walnuts (Juglans section Rhysocaryon) are native nut trees of the NEW WORLD, with a broad distribution ranging from southern Canada to northern Argentina.
Hang Ye, Hengzhao Liu, Huijuan Zhou, Jiayu Ma, Keith Woeste, Peng Zhao   +5 more
wiley   +1 more source

Diarylheptanoids of Alpinia Species (Zingiberaceae): A Review of Phytochemistry and Pharmacological Potential

Journal of Pharmacy
Introduction: Diarylheptanoids, a distinctive class of secondary metabolites characterized by a 1,7-diphenylheptane backbone, are widely distributed in Alpinia species (Zingiberaceae) and have attracted considerable scientific interest due to their ...
Wan Mohd Nuzul Hakimi Wan Salleh
doaj   +1 more source

Oregonin from Alnus incana bark affects DNA methyltransferases expression and mitochondrial DNA copies in mouse embryonic fibroblasts

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Oregonin is an open-chain diarylheptanoid isolated from Alnus incana bark that possesses remarkable antioxidant and anti-inflammatory properties, inhibits adipogenesis, and can be used in the prevention of obesity and related metabolic disorders.
Jelena Krasilnikova, Liga Lauberte, Elena Stoyanova, Desislava Abadjieva, Mihail Chervenkov, Mattia Mori, Elisa De Paolis, Vanya Mladenova, Galina Telysheva, Bruno Botta, Elena Kistanova   +10 more
doaj   +1 more source

Cysteine-specific Chemical Proteomics: From Target Identification to Drug Discovery

CHIMIA, 2016
Our laboratory focuses on chemical proteomics-enabled discovery of new cysteine-reactive small molecules with intriguing biomedical activities as well as identification and detailed characterization of their proteomic targets.
Dominic G. Hoch, Daniel Abegg, Chao Wang, Anton Shuster, Alexander Adibekian   +4 more
doaj   +1 more source

Diarylheptanoid 7-(3,4-Dihydroxyphenyl)-5- Hydroxy-1-Phenyl- (1E)-1-Heptene from Curcuma Comosa Roxb. Inhibits Nucleophosmin Localization and Induces Apoptosis in KG-1a Leukemic Stem Cells

Journal of Health Science and Medical Research (JHSMR)
Objective: This study aimed to investigate the effect of the diarylheptanoid 7-(3,4-dihydroxyphenyl)-5- hydroxy-1-phenyl-(1E)-1-heptene (DDHPH) from the rhizome of Curcuma comosa Roxb.
Natsima Viriyaadhammaa, Suwit Duangmano, Pawaret Panyajai, Khin Khin Gyi, Singkome Tima, Sawitree Chiampanichayakul, Siriporn Okonogi, Pornngarm Dejkriengkraikul, Jeffrey Krise, Aroonchai Saiai, Songyot Anuchapreeda   +10 more
doaj   +1 more source

Comprehensive widely targeted metabolomics to decipher the molecular mechanisms of Dioscorea opposita thunb. cv. Tiegun quality formation during harvest

Food Chemistry: X
Dioscorea opposita Thumb. cv. Tiegun is commonly consumed as both food and traditional Chinese medicine, which has a history of more than two thousand years.
Li An, Yongliang Yuan, He Chen, Meng Li, Jingwei Ma, Juan Zhou, Lufei Zheng, Huan Ma, Zenglong Chen, Chenyu Hao, Xujin Wu   +10 more
doaj   +1 more source

Diarylheptanoids from gray alder

, 2023
In this investigation nine known diarylheptanoids, namely platyphyllenone, hirsutenone, alnuside A and B, platyphylloside, oregonin, platyphyllonol-5-O-β-D-xylopyranoside, oregonoyl A and oregonoyl B have been isolated from the bark of A. incana using dry column flash chromatography followed by semipreparative HPLC chromatography.
Lekić, Stefan, Novaković, Miroslav, Savić, Danica, Тrendafilova, Antoaneta, Ivanova, Viktoria, Krstić, Gordana, Tešević, Vele, Milosavljević, Slobodan   +7 more
openaire   +1 more source

Inhibition of Prostaglandin and Leukotriene Biosynthesis by Gingerols and Diarylheptanoids.

Chemical and Pharmaceutical Bulletin, 1992
The rhizomes of Zingiber officinale (ginger) and Alpinia officinarum contain potent inhibitors against prostaglandin biosynthesizing enzyme (PG synthetase). Gingerols and diarylhepatanoids were identified as active compounds. Their possible mechanism of action which was deduced from the structures of active compounds indicated that the inhibitors would
KIUCHI, Fumiyuki, IWAKAMI, Satoshi, SHIBUYA, Masaaki, HANAOKA, Fumio, SANKAWA, Ushio   +4 more
openaire   +3 more sources