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A modified Holzapfel-Ogden law for a residually stressed finite strain model of the human left ventricle in diastole [PDF]
Biomechanics and Modeling in Mechanobiology, 2013 In this work, we introduce a modified Holzapfel-Ogden hyperelastic constitutive model for ventricular myocardium that accounts for residual stresses, and we investigate the effects of residual stresses in diastole using a magnetic resonance imaging ...
Berry, C. +6 more
core +4 more sources
Mean and Variability of Lipid Measurements and Risk for Development of Subclinical Left Ventricular Diastolic Dysfunction [PDF]
Diabetes & Metabolism Journal, 2022 Background Subclinical left ventricular diastolic dysfunction (LVDD) is an emerging consequence of increased insulin resistance, and dyslipidemia is one of the few correctable risk factors of LVDD. This study evaluated the role of mean and visit-to-visit
Jiyun Park +10 more
doaj +1 more source
CLINICAL ROLE OF CRITICAL CARE ECHOCARDIOGRAPHY IN SEPTIC PATIENTS: CURRENT KNOWLEDGE AND FUTURE DIRECTIONS [PDF]
Euromediterranean Biomedical Journal, 2020 Critical care echocardiography (CCE) use is rapidly growing and echocardiography is recommended as first-line approach to patients presenting with shock.
Cristina Santonocito
doaj +1 more source
Numerical study of hemodynamics after stent implantation during the cardiac cycle
Journal of Mechanical Engineering and Sciences, 2021 The descending aortic aneurysm is one of the most catastrophic cardiovascular emergencies resulting in high mortality worldwide. Clinical observations have pointed out that stent implantation in the sick aorta should probably allow stabilization of the ...
A. Belaghit +4 more
doaj +1 more source
Early diastolic filling dynamics in diastolic dysfunction [PDF]
Cardiovascular Ultrasound, 2003 The aim of the study was to determine the relationship between the rate of peak early mitral inflow velocity and the peak early diastolic mitral annular tissue velocities in normal controls and to compare them with subjects with diastolic dysfunction.The relationship between early passive diastolic transmitral flow and peak early mitral annular ...
Gerard King +4 more
openaire +4 more sources
Pharmacology Research & Perspectives, 2021 Omecamtiv mecarbil (OM) is a novel medicine for systolic heart failure, targeting myosin to enhance cardiomyocyte performance. To assist translation to clinical practice we investigated OMs effect on explanted human failing hearts, specifically ...
Alexander Dashwood +8 more
doaj +1 more source
Inorganic phosphate accelerates cardiac myofilament relaxation in response to lengthening
Frontiers in Physiology, 2022 Myocardial relaxation in late systole is enhanced by increasing velocities of lengthening. Given that inorganic phosphate (Pi) can rebind to the force-producing myosin enzyme prior to MgADP release and hasten crossbridge detachment, we hypothesized that ...
Jane I. Wakefield +2 more
doaj +1 more source
A coupled mitral valve -- left ventricle model with fluid-structure interaction [PDF]
, 2017 Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX +11 more
core +6 more sources
Cardiovascular Research, 2000 Primary diastolic failure is typically seen in patients with hypertensive or valvular heart disease as well as in hypertrophic or restrictive cardiomyopathy but can also occur in a variety of clinical disorders, especially tachycardia and ischemia. Diastolic dysfunction has a particularly high prevalence in elderly patients and is generally associated,
Mandinov, Lazar +3 more
openaire +7 more sources
Need for Speed: The Importance of Physiological Strain Rates in Determining Myocardial Stiffness
Frontiers in Physiology, 2021 The heart is viscoelastic, meaning its compliance is inversely proportional to the speed at which it stretches. During diastolic filling, the left ventricle rapidly expands at rates where viscoelastic forces impact ventricular compliance.
Matthew A. Caporizzo +1 more
doaj +1 more source