Results 1 to 10 of about 98,521 (252)

Structure‐based finite strain modelling of the human left ventricle in diastole [PDF]

International Journal for Numerical Methods in Biomedical Engineering, 2013
Finite strain analyses of the left ventricle provide important information on heart function and have the potential to provide insights into the biomechanics of myocardial contractility in health and disease. Systolic dysfunction is the most common cause
Bishop, Buckberg, Costa, Costa, Costa, Demer, Demiray, Dokos, Guccione, Guccione, Göktepe, Holzapfel, Horowitz, Humphrey, Humphrey, Hunter, Klotz, LeGrice, May-Newman, McCulloch, McCulloch, Miehe, Nash, Novak, Omens, Paulus, Potse, Sands, Schmid, Schmid, Smaill, Stevens, Velagaleti, Vetter, Vossoughi, Wang, Wang, Xi, Yin   +38 more
exaly   +4 more sources

MDCT evaluation of dynamic changes in aortic root parameters during the cardiac cycle in patients with aortic regurgitation [PDF]

Scientific Reports
Objectives: To investigate the dynamic changes in multiple planes and parameters of the aortic root region at different phases of the cardiac cycle in patients with aortic regurgitation (AR) using multi-detector row computed tomography (MDCT). To provide
Shuai Zhang, Ting Huang, Yun Lu, Xi Guo, Quanliang Shang   +4 more
doaj   +2 more sources

Mean and Variability of Lipid Measurements and Risk for Development of Subclinical Left Ventricular Diastolic Dysfunction [PDF]

Diabetes & Metabolism Journal, 2022
Background Subclinical left ventricular diastolic dysfunction (LVDD) is an emerging consequence of increased insulin resistance, and dyslipidemia is one of the few correctable risk factors of LVDD. This study evaluated the role of mean and visit-to-visit
Jiyun Park, Mira Kang, Jiyeon Ahn, Min Young Kim, Min Sun Choi, You-Bin Lee, Gyuri Kim, Kyu Yeon Hur, Jae Hyeon Kim, Jeong Hoon Yang, Sang-Man Jin   +10 more
doaj   +1 more source

Numerical study of hemodynamics after stent implantation during the cardiac cycle

Journal of Mechanical Engineering and Sciences, 2021
The descending aortic aneurysm is one of the most catastrophic cardiovascular emergencies resulting in high mortality worldwide. Clinical observations have pointed out that stent implantation in the sick aorta should probably allow stabilization of the ...
A. Belaghit, B. Aour, M. Larabi, A. A. Tadjeddine, S. Mebarki   +4 more
doaj   +1 more source

Early diastolic filling dynamics in diastolic dysfunction [PDF]

Cardiovascular Ultrasound, 2003
The aim of the study was to determine the relationship between the rate of peak early mitral inflow velocity and the peak early diastolic mitral annular tissue velocities in normal controls and to compare them with subjects with diastolic dysfunction.The relationship between early passive diastolic transmitral flow and peak early mitral annular ...
Gerard King, Michael Walsh, Faisal Almane, J B Foley, Peter A. Crean   +4 more
openaire   +4 more sources

Diastolic heart failure: boundaries of term application

Бюллетень сибирской медицины, 2023
Important changes regarding the understanding of the pathogenesis of chronic heart failure (CHF) marked the beginning of the millennium, and its first decade was called the decade of diastology.
V. V. Kalyuzhin, A. T. Teplyakov, I. D. Bespalova, E. V. Kalyuzhina, G. E. Chernogoryuk, N. N. Terentyeva, E. V. Grakova, K. V. Kopeva, V. Yu. Usov, N. P. Garganeeva, O. A. Pavlenko, Yu. V. Gorelova   +11 more
doaj   +1 more source

CLINICAL ROLE OF CRITICAL CARE ECHOCARDIOGRAPHY IN SEPTIC PATIENTS: CURRENT KNOWLEDGE AND FUTURE DIRECTIONS [PDF]

Euromediterranean Biomedical Journal, 2020
Critical care echocardiography (CCE) use is rapidly growing and echocardiography is recommended as first-line approach to patients presenting with shock.
Cristina Santonocito
doaj   +1 more source

Effects of omecamtiv mecarbil on failing human ventricular trabeculae and interaction with (−)‐noradrenaline

Pharmacology Research & Perspectives, 2021
Omecamtiv mecarbil (OM) is a novel medicine for systolic heart failure, targeting myosin to enhance cardiomyocyte performance. To assist translation to clinical practice we investigated OMs effect on explanted human failing hearts, specifically ...
Alexander Dashwood, Elizabeth Cheesman, Yee Weng Wong, Haris Haqqani, Nicole Beard, Karen Hay, Melanie Spratt, Wandy Chan, Peter Molenaar   +8 more
doaj   +1 more source

Need for Speed: The Importance of Physiological Strain Rates in Determining Myocardial Stiffness

Frontiers in Physiology, 2021
The heart is viscoelastic, meaning its compliance is inversely proportional to the speed at which it stretches. During diastolic filling, the left ventricle rapidly expands at rates where viscoelastic forces impact ventricular compliance.
Matthew A. Caporizzo, Benjamin L. Prosser   +1 more
doaj   +1 more source

Inorganic phosphate accelerates cardiac myofilament relaxation in response to lengthening

Frontiers in Physiology, 2022
Myocardial relaxation in late systole is enhanced by increasing velocities of lengthening. Given that inorganic phosphate (Pi) can rebind to the force-producing myosin enzyme prior to MgADP release and hasten crossbridge detachment, we hypothesized that ...
Jane I. Wakefield, Stephen P. Bell, Bradley M. Palmer   +2 more
doaj   +1 more source