Results 111 to 120 of about 114,320 (373)
HINT3 expression declines after myocardial ischemia‐reperfusion injury. In male mice, loss of HINT3 worsens cardiac injury and mitochondrial dysfunction, while its overexpression is protective. HINT3 binds the mitochondrial enzyme succinate dehydrogenase (SDHA) and prevents its deacetylation by histone deacetylase 1 (HDAC1), reducing succinate ...
Jiabin Yu+7 more
wiley +1 more source
A insuficiência cardíaca (IC) é uma complexa síndrome cardiovascular com elevada prevalência, sendo que seu quadro clínico frequentemente é associado à dilatação do ventrículo, à diminuição da contratilidade e à reduzida fração de ejeção do ventrículo ...
Evandro Tinoco Mesquita+1 more
doaj +1 more source
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He+9 more
wiley +1 more source
A insuficiência cardíaca com fração de ejeção normal (ICFEN) é uma síndrome complexa que vem sendo largamente estudada, desde a última década. É causada por disfunção ventricular diastólica evidenciada por métodos complementares, como estudo hemodinâmico
Meliza Goi Roscani+2 more
doaj +1 more source
Apparatus and method for processing Korotkov sounds [PDF]
A Korotkov sound processor, used in a noninvasive automatic blood measuring system where the brachial artery is occluded by an inflatable cuff, is disclosed.
Golden, D. P., Jr.+2 more
core +1 more source
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang+10 more
wiley +1 more source
Application of NASTRAN for stress analysis of left ventricle of the heart [PDF]
Knowing the stress and strain distributions in the left ventricular wall of the heart is a prerequisite for the determination of the muscle elasticity and contractility in the process of assessing the functional status of the heart.
Pao, Y. C., Ritman, E. L., Wang, H. C.
core +1 more source
Feature Tracking Cardiac Magnetic Resonance via Deep Learning and Spline Optimization
Feature tracking Cardiac Magnetic Resonance (CMR) has recently emerged as an area of interest for quantification of regional cardiac function from balanced, steady state free precession (SSFP) cine sequences.
Bluemke, David A.+3 more
core +1 more source
Clinical Utility of Echocardiography in Former Preterm Infants with Bronchopulmonary Dysplasia. [PDF]
BackgroundThe clinical utility of echocardiography for the diagnosis of pulmonary vascular disease (PVD) in former preterm infants with bronchopulmonary dysplasia (BPD) is not established.
Fineman, Jeffrey R+6 more
core +1 more source
Molecular Creep Induced Fatigue Rupture of Fibrin Clots
Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu+5 more
wiley +1 more source