Results 111 to 120 of about 114,320 (373)

The Role of HINT3 in Myocardial Ischemia‐Reperfusion Injury in Male Mice: Mechanisms Involving SDHA and its Acetylation

open access: yesAdvanced Science, EarlyView.
HINT3 expression declines after myocardial ischemia‐reperfusion injury. In male mice, loss of HINT3 worsens cardiac injury and mitochondrial dysfunction, while its overexpression is protective. HINT3 binds the mitochondrial enzyme succinate dehydrogenase (SDHA) and prevents its deacetylation by histone deacetylase 1 (HDAC1), reducing succinate ...
Jiabin Yu   +7 more
wiley   +1 more source

Insuficiência cardíaca com fração de ejeção normal: novos critérios diagnósticos e avanços fisiopatológicos Insuficiencia cardiaca con fracción de eyección normal: nuevos criterios diagnósticos y avances fisiopatológicos Heart failure with normal ejection fraction: new diagnostic criteria and pathophysiological advances

open access: yesArquivos Brasileiros de Cardiologia, 2009
A insuficiência cardíaca (IC) é uma complexa síndrome cardiovascular com elevada prevalência, sendo que seu quadro clínico frequentemente é associado à dilatação do ventrículo, à diminuição da contratilidade e à reduzida fração de ejeção do ventrículo ...
Evandro Tinoco Mesquita   +1 more
doaj   +1 more source

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

open access: yesAdvanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He   +9 more
wiley   +1 more source

Insuficiência cardíaca com fração de ejeção normal Insuficiencia cardíaca con fracción de eyección normal Heart failure with normal ejection fraction

open access: yesArquivos Brasileiros de Cardiologia, 2010
A insuficiência cardíaca com fração de ejeção normal (ICFEN) é uma síndrome complexa que vem sendo largamente estudada, desde a última década. É causada por disfunção ventricular diastólica evidenciada por métodos complementares, como estudo hemodinâmico
Meliza Goi Roscani   +2 more
doaj   +1 more source

Apparatus and method for processing Korotkov sounds [PDF]

open access: yes, 1974
A Korotkov sound processor, used in a noninvasive automatic blood measuring system where the brachial artery is occluded by an inflatable cuff, is disclosed.
Golden, D. P., Jr.   +2 more
core   +1 more source

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

open access: yesAdvanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang   +10 more
wiley   +1 more source

Application of NASTRAN for stress analysis of left ventricle of the heart [PDF]

open access: yes, 1975
Knowing the stress and strain distributions in the left ventricular wall of the heart is a prerequisite for the determination of the muscle elasticity and contractility in the process of assessing the functional status of the heart.
Pao, Y. C., Ritman, E. L., Wang, H. C.
core   +1 more source

Feature Tracking Cardiac Magnetic Resonance via Deep Learning and Spline Optimization

open access: yes, 2017
Feature tracking Cardiac Magnetic Resonance (CMR) has recently emerged as an area of interest for quantification of regional cardiac function from balanced, steady state free precession (SSFP) cine sequences.
Bluemke, David A.   +3 more
core   +1 more source

Clinical Utility of Echocardiography in Former Preterm Infants with Bronchopulmonary Dysplasia. [PDF]

open access: yes, 2020
BackgroundThe clinical utility of echocardiography for the diagnosis of pulmonary vascular disease (PVD) in former preterm infants with bronchopulmonary dysplasia (BPD) is not established.
Fineman, Jeffrey R   +6 more
core   +1 more source

Molecular Creep Induced Fatigue Rupture of Fibrin Clots

open access: yesAdvanced Science, EarlyView.
Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu   +5 more
wiley   +1 more source

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