Passive Stiffness of Myocardium From Congenital Heart Disease and Implications for Diastole
Rajiv R Chaturvedi
exaly +2 more sources
Omecamtiv mecarbil (OM) is a novel medicine for systolic heart failure, targeting myosin to enhance cardiomyocyte performance. To assist translation to clinical practice we investigated OMs effect on explanted human failing hearts, specifically ...
Alexander Dashwood +8 more
doaj +1 more source
CLINICAL ROLE OF CRITICAL CARE ECHOCARDIOGRAPHY IN SEPTIC PATIENTS: CURRENT KNOWLEDGE AND FUTURE DIRECTIONS [PDF]
Critical care echocardiography (CCE) use is rapidly growing and echocardiography is recommended as first-line approach to patients presenting with shock.
Cristina Santonocito
doaj +1 more source
Early diastolic filling dynamics in diastolic dysfunction [PDF]
The aim of the study was to determine the relationship between the rate of peak early mitral inflow velocity and the peak early diastolic mitral annular tissue velocities in normal controls and to compare them with subjects with diastolic dysfunction.The relationship between early passive diastolic transmitral flow and peak early mitral annular ...
Crean Peter A +4 more
openaire +3 more sources
Need for Speed: The Importance of Physiological Strain Rates in Determining Myocardial Stiffness
The heart is viscoelastic, meaning its compliance is inversely proportional to the speed at which it stretches. During diastolic filling, the left ventricle rapidly expands at rates where viscoelastic forces impact ventricular compliance.
Matthew A. Caporizzo +1 more
doaj +1 more source
The significant coronary tortuosity and atherosclerotic coronary artery disease; What is the relation? [PDF]
Introduction: Although coronary tortuosity is relatively common in coronary angiograms, there is much debate over the significance of this anatomical variation.
Mohsen Khosravani-Rudpishi +2 more
doaj +1 more source
Inorganic phosphate accelerates cardiac myofilament relaxation in response to lengthening
Myocardial relaxation in late systole is enhanced by increasing velocities of lengthening. Given that inorganic phosphate (Pi) can rebind to the force-producing myosin enzyme prior to MgADP release and hasten crossbridge detachment, we hypothesized that ...
Jane I. Wakefield +2 more
doaj +1 more source
Influence of manual thrombus aspiration on left ventricular diastolic function in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention [PDF]
Introduction. Data on effects of thrombus aspiration on left ventricular diastolic function in ST-elevation myocardial infarction (STEMI) population are scarce. Objective.
Ilić Ivan +13 more
doaj +1 more source
Tissue Doppler imaging (TDI) is a noninvasive sonographic method of acquiring and quantifying myocardial velocities. This technique is used in human and small animal medicine to diagnose cardiac diseases.
Marko Legler +3 more
doaj +1 more source
Aims. Diastolic dysfunction of the left ventricle in patients with coronary artery disease affects the prognosis and is associated with the frequency of hospitalization for fi rst arisen heart failure. Methods and results.
V. D. Syvolap, Ya. V. Zemlyaniy
doaj +1 more source

