Results 91 to 100 of about 310,541 (335)

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

open access: yesAdvanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang   +22 more
wiley   +1 more source

The Clinical Significance of Subclinical Thyroid Dysfunction. [PDF]

open access: yes, 2008
Subclinical thyroid disease (SCTD) is defined as serum free T(4) and free T(3) levels within their respective reference ranges in the presence of abnormal serum TSH levels.
BIONDI, BERNADETTE, COOPER DS
core   +1 more source

The association between patterns of early respiratory disease and diastolic dysfunction in preterm infants [PDF]

open access: green, 2022
Koert de Waal   +6 more
openalex   +1 more source

Trigonelline Improves Metabolism and Cardiac Function of HFpEF Mice Via Gut Microbiome Alterations‐Mediated AMPK Activation

open access: yesAdvanced Science, EarlyView.
Metabolomics analyses reveal that trigonelline is markedly reduced in HFpEF hearts. Trigonelline supplementation alleviates metabolic disorders and improves cardiac function in HFpEF mice via gut microbiota‐mediated AMPK activation. Abstract Heart failure with preserved ejection fraction (HFpEF) is a prevalent end‐manifestation of cardiovascular ...
Zhe Cheng   +9 more
wiley   +1 more source

Association of PET-measured myocardial flow reserve with echocardiography-estimated pulmonary artery systolic pressure in patients with hypertrophic cardiomyopathy [PDF]

open access: yes, 2019
BackgroundPulmonary hypertension (PH) is a known complication of HCM and is a strong predictor of mortality. We aim to investigate the relationship between microvascular dysfunction measured by quantitative PET and PH in HCM patients.MethodsEighty-nine ...
Leal, Jeffrey P   +6 more
core   +3 more sources

Pre-Clinical Diastolic Dysfunction

open access: yesJournal of the American College of Cardiology, 2014
Pre-clinical diastolic dysfunction (PDD) has been broadly defined as left ventricular diastolic dysfunction without the diagnosis of congestive heart failure (HF) and with normal systolic function. PDD is an entity that remains poorly understood, yet has definite clinical significance.
Wan, Siu-Hin   +2 more
openaire   +2 more sources

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

open access: yesAdvanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou   +16 more
wiley   +1 more source

Diastolic dysfunction: from the discovery to the latest updates

open access: yesZaporožskij Medicinskij Žurnal, 2019
Over a long period, chronic heart failure was primarily associated with impaired contractility of the left ventricular myocardium, which is a manifestation of systolic dysfunction. Based on modern ideas about the pathophysiology of CHF syndrome, systolic
T. V. Ashcheulova   +5 more
doaj   +1 more source

The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study [PDF]

open access: yes, 2004
To evaluate the cardiovascular risk of polycystic ovary syndrome (PCOS), we investigated lipid profile, metabolic pattern, and echocardiography in 30 young women with PCOS and 30 healthy age- and body mass index (BMI)-matched women. PCOS women had higher
CASCELLA, TERESA   +7 more
core   +1 more source

Predictive Value of Triglyceride/HDL‐C Ratio for Unplanned Coronary Revascularization in Elderly Patients With Type 2 Diabetes and Coronary Artery Disease: A Retrospective Cohort Study

open access: yesAGING MEDICINE, EarlyView.
Elevated TG/HDL‐C ratio independently predicted unplanned coronary revascularization in elderly patients with type 2 diabetes and CAD, highlighting its value as a simple and accessible biomarker for long‐term risk stratification. ABSTRACT Objectives The triglyceride‐to‐high‐density lipoprotein cholesterol (TG/HDL‐C) ratio reflects atherogenic ...
Wei Zhu, Yin Zhang, Pan Gao
wiley   +1 more source

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