Results 141 to 150 of about 178,200 (246)

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Association of Different Types of Diabetic Autonomic Neuropathy With Left Ventricular Diastolic Dysfunction in Patients With Type 2 Diabetes: A Cross-Sectional Study. [PDF]

J Diabetes
Feng R, Yan D, Bai M, Ran X, Chen D, Wang C, Chen L, Lin S, He S, Liu Y, Wu M, Lei Z, Gao Y.   +12 more
europepmc   +1 more source

Maternal Diastolic Dysfunction and Left Ventricular Geometry in Gestational Hypertension

, 2001
Herbert Valensise, G. P. Novelli, B. Vasapollo, Giancarlo Di Ruzza, M. E. Romanini, Massimo Marchei, G. Larciprete, Dario Manfellotto, Carlo Romaninï, Alberto Galante   +9 more
openalex   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Severity of diastolic dysfunction predicts myocardial infarction. [PDF]

Int J Cardiol Heart Vasc
Gokhale TA, Dhande M, Mulukutla S, Marroquin OC, Thoma F, Bhonsale A, Kancharla K, Voigt A, Shalaby AA, Estes NAM, Jain SK, Saba S.   +11 more
europepmc   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Loss of RET-ROS at complex I induces diastolic dysfunction in mice that is reversed by aerobic exercise. [PDF]

Am J Physiol Heart Circ Physiol
Vujic A, Koo A, Bidault G, Miljkovic JL, James AM, Dannhorn A, Duan X, Davis LM, Abe J, Valadares J, Lee JJ, Diaz-Vegas A, Turner K, Goodwin R, Fazakerley DJ, Vidal-Puig A, Murphy MP, Krieg T.   +17 more
europepmc   +1 more source

New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part II [PDF]

, 2002
Michael R. Zile, Dirk L. Brutsaert
openalex   +1 more source

SPARCL1 and NT‐proBNP as biomarkers of right ventricular‐to‐pulmonary artery uncoupling in pulmonary hypertension

ESC Heart Failure, Volume 12, Issue 2, Page 1416-1426, April 2025.
Abstract Aims SPARCL1 was recently identified as a biomarker of right ventricular (RV) maladaptation in patients with pulmonary hypertension (PH), and N‐terminal pro‐brain natriuretic protein (NT‐proBNP) is an established biomarker of RV failure in PH. The present study investigated whether NT‐proBNP and SPARCL1 concentrations are associated with load ...
Oliver Dörr, Stanislav Keranov, Paulina van Wickern, Holger Nef, Christian Hamm, Pascal Bauer, Christian Troidl, Samuel Sossalla, Sandra Voss, Christoph Liebetrau, Manuel J. Richter, Henning Gall, Werner Seeger, Ardeschir Ghofrani, Athiththan Yogeswaran, Khodr Tello   +15 more
wiley   +1 more source

Mechanism-based myofilament manipulation to treat diastolic dysfunction in HFpEF. [PDF]

Front Physiol
Dominic KL, Schmidt AV, Granzier H, Campbell KS, Stelzer JE.   +4 more
europepmc   +1 more source