Results 151 to 160 of about 109,445 (330)

The comparative effect of Valeriana officinalis versus Diazepam on the state of anxiety before operation in female patients admitted in Kashani hospital

open access: yesMajallah-i Bālīnī-i Parastārī va Māmāyī, 2016
Background and aims: Valeriana officinalis is one of the most practical herbal medicines with anxiolytic and sedative properties. This study was conducted to compare herbal medicine V.
Golamreza Shabanian   +4 more
doaj  

Long‐term seizure and psychosocial outcomes of patients with ring chromosome 20 syndrome: A cohort study of 47 cases

open access: yesEpilepsia, EarlyView.
Abstract Objective We retrospectively investigated a cohort of patients with ring chromosome 20 syndrome (r20), aiming to provide information on the prognosis of r20 regarding seizures, cognitive function, comorbidities, and social living. Methods Patients diagnosed with r20 in our hospital were identified, and clinical data were extracted from medical
Kentaro Tokumoto   +11 more
wiley   +1 more source

Diazepam abreaction [PDF]

open access: yesBritish Journal of Psychiatry, 1991
, Adityanjee   +2 more
openaire   +2 more sources

EEG signal dimension is an index of seizure propensity and antiseizure medication effects in a mouse model of acquired epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Variability in the frequency, timing, and pattern of seizures may influence the assessment of the effect of antiseizure medications (ASMs) when measuring seizure frequency, especially in patients with infrequent seizures. A low seizure rate is an exclusion criterion for enrollment of patients with epilepsy in clinical trials and ...
Massimo Rizzi   +4 more
wiley   +1 more source

Synaptic inhibitory dynamics drive benzodiazepine response in pediatric status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Pediatric status epilepticus (SE) is a medical emergency associated with significant morbidity. Benzodiazepines (BZPs) are the current first‐line treatment, but do not work in more than one third of children presenting with SE. Animal studies have shown that SE can cause changes in synaptic inhibition signaling that can ultimately ...
Tommaso Fedele   +5 more
wiley   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

open access: yesEpilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher   +1 more
wiley   +1 more source

Status epilepticus in older adults: A critical review

open access: yesEpilepsia, EarlyView.
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward   +5 more
wiley   +1 more source

Strain-dependent effects of diazepam and the 5-HT2B/2C receptor antagonist SB 206553 in spontaneously hypertensive and Lewis rats tested in the elevated plus-maze

open access: yesBrazilian Journal of Medical and Biological Research, 2001
The 5-HT2B/2C receptor antagonist SB 206553 exerts anxiolytic effects in rat models of anxiety. However, these effects have been reported for standard rat strains, thus raising the issue of SB 206553 effects in rat strains displaying different levels of ...
Takahashi R.N.   +3 more
doaj  

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