Results 211 to 220 of about 83,280 (287)

Curcumin Modulates PTPRZ1 Activity and RNA m6A Modifications in Neuroinflammation‐Associated Microglial Response

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
Wenxiang Meng and colleagues delve into the molecular mechanisms underlying curcumin's modulation of RNA post‐transcriptional N (6)‐methyladenosine (m6A) modification. It is found that curcumin interacts with the Z1‐type protein tyrosine phosphatase receptor (PTPRZ1), maintaining its enzymatic activity and thus regulating the phosphorylation of the m6A‐
Ninan Zhang   +9 more
wiley   +1 more source

BILIARY EXCRETION OF DIAZEPAM IN MAN

open access: bronze, 1975
PATRICIA EUSTACE   +3 more
openalex   +1 more source

Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep

open access: yesBrain and Behavior, Volume 15, Issue 4, April 2025.
Sheep with CLN5 Batten disease that received combination intracerebroventricular and intravitreal gene therapy underwent MRI scanning to assess global and regional brain volumes and determine the value of MRI to detect therapeutic efficacy. Sheep that were treated pre‐symptomatically underwent longitudinal scanning between 5 and 18 months of age, while
Samantha J. Murray   +11 more
wiley   +1 more source

An Italian Survey on the Management of Pediatric Convulsive Status Epilepticus: More Than Just a Pharmacological Choice

open access: yesBrain and Behavior, Volume 15, Issue 4, April 2025.
A survey exploring specialists’ opinions on the current management of pediatric convulsive status epilepticus (CSE) in Italy confirms that first‐line treatment of pediatric CSE relies on intravenous MDZ and that heterogeneity of therapeutic choices starts from the second‐line treatment. Answers’ variability concerning organizational aspects such as the
Caterina Zanus   +12 more
wiley   +1 more source

Respiratory Function Following Prernedication with Droperidol or Diazepam

open access: bronze, 1978
DAVID SOROKER   +3 more
openalex   +1 more source

Is annual screening by fecal immunochemical test necessary after a recent colonoscopy?

open access: yesDEN Open, Volume 5, Issue 1, April 2025.
Abstract Objective The population‐based colorectal cancer screening guidelines in Japan recommend an annual fecal immunochemical test (FIT). However, there is no consensus on the need for annual FIT screening for patients who recently performed a total colonoscopy (TCS).
Yutaka Okagawa   +11 more
wiley   +1 more source

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