Results 41 to 50 of about 83,280 (287)
Frontiers in Medicine, 2021 Objective: Due to the extensive use of diazepam worldwide, self-induced intoxication is very common, yet rarely fatal. Nevertheless, the management of intoxication caused by extremely high doses of diazepam is not known, as well as the effectiveness of ...
Anna Dobisova +5 more
doaj +1 more source
New England Journal of Medicine, 2001 BACKGROUND It is uncertain whether the administration of benzodiazepines by paramedics is an effective and safe treatment for out-of-hospital status epilepticus.
B. Alldredge +11 more
semanticscholar +1 more source
Preconcentration and determination of diazepam in pharmaceutical and biological samples by graphene oxide based on dispersive solid phase microextraction [PDF]
شیمی کاربردی روز, 2019 Graphene oxide (GO) has a great potential to use as an adsorbent in sample preparation procedures. In this research, GO was used as an effective adsorbent in a simple GO-based dispersive micro-solid phase extraction technique coupled with high ...
Nazpari Mirzaei +2 more
doaj +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 132, Issue 1, Page 21-32, January 2023., 2023 Abstract Uric acid has promoted renal fibrosis and inflammation in experimental studies, but some studies have shown nephroprotective effects due to alleviated oxidative stress. We studied the influence of experimental hyperuricaemia in surgically 5/6 nephrectomized rats. Three weeks after subtotal nephrectomy or sham operation, the rats were allocated
Venla Kurra +9 more
wiley +1 more source
Effect of diazepam on kidney function and histological structure of white rat’s kidney
Journal of Biological Researches, 2016 The use of NAPZA (Narcotics, Alcohol, Psychotropic, and other addictive substances) in Indonesia keeps increasing. One type of frequently used NAPZAs is diazepam. Diazepam is a kind of sedative-hypnotics drug which belongs to benzodiazepine.
Putu Gede Martha Setiawan +2 more
doaj +1 more source
Anxiolytic activity of Berberis aristata root extract in mice
BLDE University Journal of Health Sciences, 2020 BACKGROUND: Anxiety is a common emotional response in humans and it is one of most common psychiatric illnesses. Interest in herbal drugs is growing nowadays for the optimum treatment of anxiety. The aim of the present study was to explore the anxiolytic
Divya Goel
doaj +1 more source
Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.
Proceedings of the National Academy of Sciences of the United States of America, 1977 [3H]Diazepam appears to bind specifically to a single, saturable, binding site located on rat brain membranes, with an affinity constant near 3 nM at pH 7.4.
C. Braestrup, R. Squires
semanticscholar +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 132, Issue 1, Page 111-119, January 2023., 2023 Abstract Information regarding deaths caused by poisoning or adverse effects of medication in Danish persons not using illicit narcotic drugs (PNUIDs) is sparse. To characterize aetiology, demographics, and death scene, we reviewed all legal autopsies performed at Aarhus University from 2017 to 2019 and isolated 96 deaths caused by medications in ...
Charlotte U. Andersen +4 more
wiley +1 more source
Archives of Anesthesia and Critical Care, 2019 Background: The purpose of this study was the evaluation of diazepam administration on perioperative blood pressure in hypertensive patients who undergoing cataract surgery.
Mehdi Sanatkar +3 more
doaj +1 more source