Results 61 to 70 of about 98,705 (330)
Drug Testing and Analysis, EarlyView.A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki +10 more
wiley +1 more source
Central muscle relaxant effects of diazepam [PDF]
, 1970 Motor depressant effects of diazepam were studied in the intact, decerebrate and high spinal cat. Diazepam (0[middle dot]125-16 mg/kg i.v.) produced a depression of both the patellar and linguomandibular reflexes in the intact cat. In the high spinal (C1)
Hudson, Roy D., Wolpert, Mary K.
core +1 more source
Anxiolytic activity of Berberis aristata root extract in mice
BLDE University Journal of Health Sciences, 2020 BACKGROUND: Anxiety is a common emotional response in humans and it is one of most common psychiatric illnesses. Interest in herbal drugs is growing nowadays for the optimum treatment of anxiety. The aim of the present study was to explore the anxiolytic
Divya Goel
doaj +1 more source
Drug Testing and Analysis, EarlyView.Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani +6 more
wiley +1 more source
The Role of Nitrous Oxide (“Laughing Gas”) in DUID Cases and Its Impact on Driving Fitness
Drug Testing and Analysis, EarlyView.A total number of 39 cases of driving under the influence of nitrous oxide were investigated. Plasma concentrations of 0.22 to 17 mL/L (median:3.7 mL/L) were measured in blood samples withdrawn 38 to 144 min (median: 85 min) after control via Headspace‐GC–MS.
L. Lucuta +4 more
wiley +1 more source
TEN-YEAR RETROSPECTIVE STUDY OF DIAZEPAM CONSUMPTION IN INDONESIA [PDF]
, 2017 Objective: This study aimed to evaluate annual consumption during 2004-2013 of diazepam, an essential medicine which is controlled under the 1971 Convention on Psychotropic Substances in Indonesia and to investigate factors influencing its use in health ...
Suryawati, Sri +7 more
core +1 more source
Preconcentration and determination of diazepam in pharmaceutical and biological samples by graphene oxide based on dispersive solid phase microextraction [PDF]
شیمی کاربردی روز, 2019 Graphene oxide (GO) has a great potential to use as an adsorbent in sample preparation procedures. In this research, GO was used as an effective adsorbent in a simple GO-based dispersive micro-solid phase extraction technique coupled with high ...
Nazpari Mirzaei +2 more
doaj +1 more source
GABAA Receptor α Subunits Differentially Contribute to Diazepam Tolerance after Chronic Treatment
PLoS ONE, 2012 Background Within the GABAA-receptor field, two important questions are what molecular mechanisms underlie benzodiazepine tolerance, and whether tolerance can be ascribed to certain GABAA-receptor subtypes.
C. Vinkers +7 more
semanticscholar +1 more source
Epilepsia, EarlyView.Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku +4 more
wiley +1 more source
Clinical Case Reports, 2023 Stiff Person Syndrome (SPS), a progressive Central Nervous System disorder is accompanied by progressive muscle rigidity, hyperreflexia, and spasms mainly in truncal and proximal leg muscles mainly associated with autoimmune disorders.
Sanjeev Kharel +9 more
doaj +1 more source