Results 51 to 60 of about 98,705 (330)

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Comparison of Effectiveness and Side Effects of Diazepam versus Midazolam Administration for Conscious Sedation in Patients Who Underwent Cataract Surgery

Archives of Anesthesia and Critical Care, 2019
Background: The purpose of this study was to compare the effectiveness and side effects of diazepam and midazolam administration for conscious sedation in subjects who undergoing cataract surgery.
Mehdi Sanatkar, Mehrdad Shorooghi, Mohammad Sadegh Sanie   +2 more
doaj   +1 more source

Cellular localization of [3H]-diazepam receptors

, 1978
Isolated fractions enriched in bovine cortical astroglial cells or nerve endings were used to determine the receptor site for [3H]-diazepam binding. The results suggest strong enrichment in glial cells for the benzodiazepine receptor. Both the inhibition
Henke, D. J., Henn, F. A.
core   +1 more source

An ETH‐LAD trip with unfavourable consequences: A case report

British Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler, Michaela Sommer, Annette Zschiesche, Anne Stürzebecher, Christina Grumann, Volker Auwärter, Maren Hermanns‐Clausen   +6 more
wiley   +1 more source

Adaptação a um novo ambiente em pombos (Columba Livia): descrição comportamental e os efeitos da administração sistêmica de diazepam [PDF]

, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.Descrição do repertório comportamental de pombos (Columba lívia) submetidos à um novo ambiente.
Souza, Amanda Cristina Braz de
core  

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

Diazepam-like effects of medicinal plants: A possible approach or a complementary method

, 2014
Since the introduction of diazepam (DZP) by Sternbach in the 1950s, few drugs acting on GABA receptors that do not belong to the class of benzodiazepines have been introduced in therapy. DZP is one of the most prescribed drugs in clinical practice; there
Almeida-Júnior, L. D., Costa, C. A.R.A.
core   +1 more source

Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences

British Journal of Clinical Pharmacology, EarlyView.
Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry, Muhammad Umair Khan, Barbara Conway, Syed Shahzad Hasan   +3 more
wiley   +1 more source

Sedative Potential of L (+)-Tartaric Acid: Behavioral Evidence With In Silico Insights Into Possible GABAergic Interaction. [PDF]

Brain Behav
ABSTRACT Purpose Insomnia is a prevalent neurological disorder often caused by stress, anxiety, and imbalances in the GABAergic system. Although benzodiazepines like diazepam (DZP) are commonly prescribed, their long‐term use is associated with adverse effects, including dependence and impaired coordination.
Bithi SA, Chakrabarty A, Akter K, Saha CK, Alshahrani MY, Hossain MA, Mia E, Yana NT, Ajmee A, Mandal P, Al Hasan MS, Islam MT.   +11 more
europepmc   +2 more sources

Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands

Nature Chemical Biology, 2012
Benzodiazepines exert their anxiolytic, anticonvulsant, muscle-relaxant and sedative-hypnotic properties by allosterically enhancing the action of GABA at GABAA receptors via their benzodiazepine-binding site.
L. Richter, C. de Graaf, W. Sieghart, Zdravko Varagić, M. Mörzinger, I. D. de Esch, G. Ecker, M. Ernst   +7 more
semanticscholar   +1 more source