Results 141 to 150 of about 1,703,017 (234)
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
FeIII‐Mediated Synthesis of Azaspirodienones via Ipso‐Radical Cyclization of Ugi–4CR Adducts
An efficient two‐step protocol for the synthesis of azaspirodienones via Fe‐mediated ipso‐radical cyclization of Ugi adducts has been developed. This methodology provides rapid access to these privileged spirocyclic architectures under mild conditions, offering a practical and versatile approach to generating structurally complex molecules with ...
Silvia J. Becerra–Anaya +2 more
wiley +1 more source
Cobalt Diazo-Compounds: From Nitrilimide to Isocyanoamide via a Diazomethanediide Fleeting Intermediate. [PDF]
Aghazada S +4 more
europepmc +1 more source
Atom insertion represents a powerful yet conceptually challenging mode of skeletal editing, as it requires controlled cleavage and reorganization of strong covalent bonds within an existing molecular framework.
Yuki Konno, Mahito Atobe, Naoki Shida
doaj +1 more source
The Expanding Role of Diazirines in Synthetic Methodology
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic +3 more
wiley +1 more source
Visible Light Induced Brønsted Acid Assisted Pd-Catalyzed Alkyl Heck Reaction of Diazo Compounds and N-Tosylhydrazones. [PDF]
Zhang Z +3 more
europepmc +1 more source
Yoshiro OGATA, Masaru TSUCHIDA
openaire +3 more sources
Stereoselective Synthesis of Tri- and Tetrasubstituted Olefins via 1,6-Additions of Diazo Compounds and Their Precursors to p-Quinone Methides. [PDF]
Pati S, Rayi S, Namboothiri INN.
europepmc +1 more source
Understanding the Influence of Donor-Acceptor Diazo Compounds on the Catalyst Efficiency of B(C6 F5 )3 Towards Carbene Formation. [PDF]
Babaahmadi R +5 more
europepmc +1 more source
Yoshiro OGATA, Yasuo TAKAGI
openaire +3 more sources

