Results 141 to 150 of about 1,703,017 (234)

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

open access: yesChemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

FeIII‐Mediated Synthesis of Azaspirodienones via Ipso‐Radical Cyclization of Ugi–4CR Adducts

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.
An efficient two‐step protocol for the synthesis of azaspirodienones via Fe‐mediated ipso‐radical cyclization of Ugi adducts has been developed. This methodology provides rapid access to these privileged spirocyclic architectures under mild conditions, offering a practical and versatile approach to generating structurally complex molecules with ...
Silvia J. Becerra–Anaya   +2 more
wiley   +1 more source

Electrochemical Three‐Atom Insertion via [3 + 2] Cycloaddition of Thionium Cations and Diazo Compounds

open access: yesChemElectroChem
Atom insertion represents a powerful yet conceptually challenging mode of skeletal editing, as it requires controlled cleavage and reorganization of strong covalent bonds within an existing molecular framework.
Yuki Konno, Mahito Atobe, Naoki Shida
doaj   +1 more source

The Expanding Role of Diazirines in Synthetic Methodology

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 38, 13 October 2026.
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic   +3 more
wiley   +1 more source

Reactions of Diazo Compounds

open access: yesJournal of Synthetic Organic Chemistry, Japan, 1956
Yoshiro OGATA, Masaru TSUCHIDA
openaire   +3 more sources

Reactions of Diazo Compounds

open access: yesJournal of Synthetic Organic Chemistry, Japan, 1957
Yoshiro OGATA, Yasuo TAKAGI
openaire   +3 more sources

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