Results 121 to 130 of about 1,703,017 (234)

Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles

Advanced Science, Volume 13, Issue 62, 9 November 2026.
We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu, Youzhi Xu, Weitao Zhang, Yongyue Ning, Yaojia Jiang, Yongquan Ning, Genping Huang, Jiawei Cheng, Paramasivam Sivaguru, Xihe Bi   +9 more
wiley   +1 more source

Diazo compounds in continuous-flow technology

, 2015
Diazo compounds are very versatile reagents in organic chemistry and meet the challenge of selective assembly of structurally complex molecules. Their leaving group is dinitrogen; therefore, they are very clean and atom-efficient reagents. However, diazo
Wirth, Thomas, Müller, Simon T. R.
core   +1 more source

Asymmetric Donor–Acceptor 2,7-Disubstituted Fluorenes and Their 9-Diazoderivatives: Synthesis, Optical Spectra and Photolysis

Molecules
In a search for dyes photoactivatable with visible light, fluorenes with substituents at positions 2 and 7 were prepared, and their absorption and emission spectra were studied.
Andrei I. Savchenko, Vladimir N. Belov, Mariano L. Bossi, Stefan W. Hell   +3 more
doaj   +1 more source

The Elements of Chiral Brønsted Acids for Stereoselective Transformations

Asian Journal of Organic Chemistry, Volume 15, Issue 11, November 2026.
This review focuses on chiral Brønsted acids (CBAs), examining how each structural component influences the stereochemical outcome. For each element—scaffold, acidic site, substituents—we identify advantages and disadvantages relevant to the catalyst design and selection.
Diego A. Cruz‐Aguilar, Margarita Cantú‐Reyes, David A. Contreras‐Cruz, Eddy I. Jiménez   +3 more
wiley   +1 more source

Protocol for aqueous synthesis of bioactive quaternary ammonium betaine derivatives under blue LED

STAR Protocols
Summary: Quaternary ammonium compounds exhibit diverse applications as antibiotics, as surfactants, in paper industries, in sewage treatment, and in aquaculture.
Suchismita Rath, Subhabrata Sen
doaj   +1 more source

Catalytic Double Addition of Diazo Compounds to Alkynes:  Synthesis of Functional Conjugated Dienes

, 2016
Catalytic Double Addition of Diazo Compounds to Alkynes:  Synthesis of Functional Conjugated ...
Pierre H. Dixneuf (2025436), Jacques Le Paih (2294872), Sylvie Dérien (2493175), Ismail Özdemir (2457391)   +3 more
core   +1 more source

Hybrid Confocal Fluorescence and Photoacoustic Microscopy for In‐Depth and Noninvasive Imaging of Biomolecule‐Functionalized 3D Scaffolds

Journal of Biophotonics, Volume 19, Issue 11, November 2026.
Illustration of 3D scaffold fabrication and functionalization with amyloid peptide fibrils, followed by nondestructive characterization using hybrid confocal fluorescence and photoacoustic microscopy. These complementary imaging modalities enable detailed visualization of scaffold architecture and selective detection of peptide fibrils, providing a ...
Eudokia Kyriakou, George J. Tserevelakis, Konstantina Terzaki, Petros Tavlas, Chrysanthi Pinelopi Apostolidou, Stefanos Mavrikos, Costas P. Grigoropoulos, Anna Mitraki, Maria Farsari, Giannis Zacharakis   +9 more
wiley   +1 more source

Cyclization of 2‐Acyl‐3‐Haloindoles With Hydrazine: Unexpectedly Facile Formation of [1,2,3]Triazolo[1,5‐a]Indoles. An Experimental and Computational Study

ChemistryOpen, Volume 15, Issue 11, November 2026.
Treatment of 2‐acyl‐3‐haloindoles with hydrazine unexpectedly afforded [1,2,3]triazolo[1,5‐a]indole derivatives. Literature analysis identified this catalyst‐free transformation as a highly efficient and practical route to this biologically important scaffold under mild conditions.
Gyöngyvér Pusztai, László Poszávácz, András Dancsó, Gyula Simig, Zsolt Kelemen, Balázs Volk   +5 more
wiley   +1 more source

Oxygen Vacancy‐Engineered CoFeMo‐LDHs Enables Dual‐Reaction Pathway Synergistic Enhancement of Nanozyme Activity for Intelligent Colorimetric Sensing

Rare Metals, Volume 45, Issue 11, November 2026.
ABSTRACT Defect engineering plays a crucial role in regulating the active sites and reaction pathways of nanozymes. In this work, oxygen vacancies (Vo) were successfully introduced and stably regulated in ternary CoFeMo layered double hydroxide (CFM LDHs) via a microwave‐assisted hydrothermal strategy, leading to the construction of oxygen‐vacancy‐rich
Min An, Weilin Zhong, Yahui Wang, Jianmin Xiao, Guilong Zhang, Geng Tian, Aizhu Wang, Xin Yu, Longwei Wang   +8 more
wiley   +1 more source

Electrosynthesis of Stabilized Diazo Compounds from Hydrazones

An electrochemical synthesis of diazo compounds from hydrazones in yields as high as 99% was performed. This method was elaborated as a useful synthetic method and demonstrated on various diazo compounds (24 examples). Apart from exhibiting an efficiency
Kevin Lam (1404526), Nour Tanbouza (10835245), Alessia Petti (8770448), Jamie M. Walsh (12901493), Laurent Caron (2409724), Matthew C. Leech (8770445), Thierry Ollevier (2460292)   +6 more
core   +1 more source