Diazo Transfer Reactions to 1,3-Dicarbonyl Compounds with Tosyl azide [PDF]
, 2011 International audienceA practical protocol for the large-scale preparation of 2-diazo-1,3-dicarbonyl compounds is described by diazo-transfer reactions with tosyl azide followed by efficient chromatographic purifications on silica gel and/or ...
Coquerel, Yoann +3 more
core +2 more sources
Electrosynthesis of Stabilized Diazo Compounds from Hydrazones
Organic Letters, 2022 An electrochemical synthesis of diazo compounds from hydrazones in yields as high as 99% was performed. This method was elaborated as a useful synthetic method and demonstrated on various diazo compounds (24 examples). Apart from exhibiting an efficiency that matched that of commonly used harsh and toxic chemical oxidants, this reaction is practically ...
Nour Tanbouza +6 more
openaire +2 more sources
Direct Laser Writing of Magnetic Micro Actuators With a Stimulus‐Responsive Compliant Hinge
Advanced Materials Technologies, EarlyView.This study presents a versatile modular design strategy for adaptive 3D microactuators. Using two‐photon‐induced C,H insertion reactions within solid polymer layers, chemically distinct hinge and stimulus responsive materials are patterned in one step. The hinge's properties enable tunable motion, mechanical control, and reconfigurable actuation across
Eleonora Galli +4 more
wiley +1 more source
Rapid Assembly of the Salvileucalin B Norcaradiene Core [PDF]
, 2010 Preparation of the polycyclic core of the cytotoxic natural product salvileucalin B is described. The key feature of this synthetic strategy is a copper-catalyzed intramolecular arene cyclopropanation to provide the central norcaradiene.
Levin, Sergiy +2 more
core +1 more source
Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]
, 2016 The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA +4 more
core +1 more source
Structurally Enhanced Colloidal Molecules via Carbene‐Mediated Covalent C─H Insertion Crosslinking
Advanced Science, EarlyView.This work presents a nonspecific covalent crosslinking strategy to significantly enhance the structural stability of colloidal molecules (CMs) without compromising their inherent structural and physicochemical properties by rationally designing a diazo‐based crosslinker.
Liwei Dai +7 more
wiley +1 more source
Facile and diastereoselective arylation of the privileged 1,4-dihydroisoquinolin-3(2H)-one scaffold
Beilstein Journal of Organic Chemistry, 2022 A practically convenient and streamlined protocol for the trans-diastereoselective introduction of an aryl substituent at position 4 of the 1,4-dihydroisoquinol-3-one (1,4-DHIQ) scaffold is presented.
Dmitry Dar’in +3 more
doaj +1 more source
2-Diazoacetoacetic acid, an efficient and convenient reagent for the synthesis of alpha-diazo-beta-ketoesters [PDF]
, 2006 The formation of various alpha-diazo acetoacetic esters can be obtained in a single transformation with good to excellent yields using readily available 2-diazoacetoacetic ...
Ferreira, Eric M. +2 more
core
A Biocatalytic Platform for Synthesis of Chiral α-Trifluoromethylated Organoborons [PDF]
, 2018 There are few biocatalytic transformations that produce fluorine-containing molecules prevalent in modern pharmaceuticals. To expand the scope of biocatalysis for organofluorine synthesis, we have developed an enzymatic platform for highly ...
Arnold, Frances H. +6 more
core +3 more sources
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow-Generated Diazo Compounds and Propargylated Amines. [PDF]
Angew Chem Int Ed Engl, 2017 Poh JS +6 more
europepmc +2 more sources