Results 41 to 50 of about 21,735 (237)

Ultrasound Assisted Synthesis Of Pyrazolone Derivatives [PDF]

مجلة التربية والعلم, 2013
The diazonium salt of 4-amino-1,5-dimethyl-2-phenyl-1H-pyrazol- 2-one (4-aminoantipyrine) was coupled with ethylacetoacetate and ethyl benzoylacetate to give the corresponding diazo compounds under basic media.
Badie Ahmed, Jasim Abdullah
doaj   +1 more source

Characterization of a Reductively-Activated Elimination Pathway Relevant to the Biological Chemistry of the Kinamycins and Lomaiviticins [PDF]

, 2012
The lomaiviticins (1 and 2) and kinamycins (3–5) are bacterial metabolites with potent antimicrobial and antiproliferative activities. Herein we establish that 1–5 are capable of generating electrophilic acylfulvene intermediates (6) under mildly ...
Ding, Weidong, Ellestad, George A., Herzon, Seth B., Mulcahy, Seann P., Woo, Christina M.   +4 more
core   +3 more sources

Copper-catalyzed 2,3-dihydro-1,2,4-triazoles synthesis through [3+2]-cycloaddition of nitrile ylides with azodicarboxylates

Green Synthesis and Catalysis
A copper-catalyzed three-component reaction of diazo compounds, nitriles, and azodicarboxylates to construct 2,3-dihydro-1,2,4-triazoles is reported. Key to the success is the utilization of azodicarboxylates to trap the in-situ formed nitrile ylides ...
Bao-Gui Cai, Qian Li, Jun Xuan
doaj   +1 more source

Asymmetric formal C–C bond insertion into aldehydes via copper-catalyzed diyne cyclization

Nature Communications, 2023
The formal C–C bond insertion into aldehydes is an attractive methodology for the assembly of homologated carbonyl compounds. However, the homologation of aldehydes has been limited to diazo approach and the enantioselective reaction was rarely developed.
Cui-Ting Li, Lin-Jun Qi, Li-Gao Liu, Chang Ge, Xin Lu, Long-Wu Ye, Bo Zhou   +6 more
doaj   +1 more source

Spiro‑Linked Double Tetraphenylethenes: Solid‐State Emission and Circularly Polarized Luminescence Imaging

Angewandte Chemie, EarlyView.
Two spirobisanthracene‐tetraphenylethene (SBA‐TPE) hybrid compounds are synthesized and their photophysical properties in the solid state reported. Circularly polarized luminescence in aggregates, films and dispersions is evaluated. Circularly polarized luminescence imaging is evaluated over crystals revealing discrimination of different types of ...
José L. Páez, Riccardo Rubino, Giulia Micolonghi, Marco Reale, Alice Sciortino, Victor Blanco, Angel Orte, Carlos M. Cruz   +7 more
wiley   +2 more sources

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives

Molecules, 2021
Synthetic heterocyclic compounds have incredible potential against different diseases; pyridines, phenolic compounds and the derivatives of azo moiety have shown excellent antimicrobial, antiviral, antidiabetic, anti-melanogenic, anti-ulcer, anticancer ...
Tehreem Tahir, Muhammad Ashfaq, Muhammad Saleem, Muhammad Rafiq, Mirza Imran Shahzad, Katarzyna Kotwica-Mojzych, Mariusz Mojzych   +6 more
doaj   +1 more source

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]

, 2013
The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E., Arrowsmith J., Barvaux V. A., Boberg F., Boyd M. R., Bunz F., Damera K., Darkes M. J. M., De K., Denny B. J., Dimitrios Pletsas, Dinca E. B., Elrashied A. E. Garelnabi, Garelnabi E. A. E., Hirose Y., Honnalli S. S., Judson P. L., Karran P., Karran P., Kotera M., Leteurtre F., Li Li, Liu L., McElhinney R. S., McGarrity J. F., Mladek A. C., Nishizuka S., Pletsas D., Richard T. Wheelhouse, Roger M. Phillips, Sarkaria J. N., Schmidt B. F., Schmiedekamp A., Shealy Y. F., Siddiqui A. A., Smith R. H., Stevens M. F. G., Svilar D., Wang Y., Wheelhouse R. T., Wheelhouse R. T., Zhang J., Zhang J.   +42 more
core   +1 more source

Traditional and New methods for the Preparation of Diazocarbonyl Compounds

Anais da Academia Brasileira de Ciências, 2018
For many years diazocarbonyl compounds have been studied due to their versatility and usability in many chemical transformations. In this review, we summarize the traditional methods to prepare these compounds as well as the new methods and recent ...
ANTONIO C.B. BURTOLOSO, PATRÍCIA B. MOMO, GRAZIELE L. NOVAIS   +2 more
doaj   +1 more source

Enantioselective three-component aminomethylation of α-diazo ketones with alcohols and 1,3,5-triazines

Nature Communications, 2020
Strategies for enantioselective α-aminomethylation of carbonyl compounds rely on the chiral activation of stable ketones substrate. Here, the authors report a rhodium/chiral phosphoric acid cooperative catalysis for the three-component reaction of α ...
Jiuwei Che, Li Niu, Shikun Jia, Dong Xing, Wenhao Hu   +4 more
doaj   +1 more source

Recent Advances in the Synthesis of Aromatic Azo Compounds

Molecules, 2023
Aromatic azo compounds have -N=N- double bonds as well as a larger π electron conjugation system, which endows aromatic azo compounds with wide applications in the fields of functional materials.
Meng-Yun Zhao, Yue-Feng Tang, Guo-Zhi Han   +2 more
doaj   +1 more source