O-methyltransferase-like enzyme catalyzed diazo installation in polyketide biosynthesis
Nature Communications, 2023 Diazo compounds are rare natural products possessing various biological activities. Kinamycin and lomaiviticin, two diazo natural products featured by the diazobenzofluorene core, exhibit exceptional potency as chemotherapeutic agents.
Yuchun Zhao +14 more
doaj +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan +22 more
wiley +1 more source
Chemoselective carbene insertion into the N−H bonds of NH3·H2O
Nature Communications, 2022 Converting low-cost inorganic chemicals into value-added organic chemicals is a longstanding goal in chemistry. Here the authors describe a silver-catalysed chemoselective carbene N−H insertion reaction, providing access to primary amines from aqueous ...
Zhaohong Liu +8 more
doaj +1 more source
Radical Cascade Multicomponent Minisci Reactions with Diazo Compounds
, 2022 Based on the strategy of polarity reversal in the generation of free radicals derived from diazo compounds, photocatalyzed multicomponent reactions (MCRs) of nitrogen aromatic heterocycles, alkenes, and diazo compounds form functionalized derivatives in ...
Geng-Xin Liu (9191937) +8 more
core +3 more sources
Construction of a femtosecond pump-probe spectroscopy system and experiments on the photochemistry of 1-diazo-indan-2-one derivates [PDF]
, 2006 The aim of this work was the investigation of 3-diazo-2-indolinone photoreactions as a part of the larger project concerning 1-diazo-2-indanone derivatives1.
Gáplovský, Martin
core +1 more source
Pd-Catalyzed 1,4-Carboamination of Bromoarenes with Diazo Compounds and Amines [PDF]
, 2022 A palladium-catalyzed 1,4-carboamination of bromoarenes with diazo compounds and amines was developed. This reaction proceeds through a palladium-carbene that then generates a π-benzylpalladium intermediate, forming ipso C–C and para C–N bonds on ...
Junichiro, Yamaguchi +2 more
core +2 more sources
Nucleophilicities of Cyclic α‐Diazo Carbonyl Compounds [PDF]
, 2023 The kinetics of the reactions of cyclic α-diazo carbonyl compounds with electrophilic benzhydrylium ions were evaluated to determine the Mayr reactivity descriptors N (and sN) of the nucleophiles.
Jer‐Ray Hsu +7 more
core +1 more source
Copper-Catalyzed Insertion of Diazo Compounds into Vinyl Hypervalent Iodine Reagents to Generate Allylic Esters [PDF]
, 2019 An unprecedented copper(I)-catalyzed vinylation of (donor)-acceptor diazo compounds with VinylBenziodoXolone reagents (VBX) as partners is reported. The transformation tolerates variation of both donor- and acceptor substituents on the diazo compounds ...
Guillaume, Pisella +5 more
core +1 more source
Synthesis of Tetrasubstituted Allenes via Palladium-Catalyzed Cross-Coupling of Vinyl Bromides with Diazo Compounds [PDF]
, 2019 A highly efficient palladium-catalyzed cross-coupling of 2,2-diarylvinyl bromides with diazo compounds was developed, providing a convenient approach for the synthesis of tetrasubsti-tuted allenes. Both aryl diazo carbonyl compounds and N-tosylhydrazones
Chen-Guo, Feng +7 more
core +1 more source
C.—The constitution of the diazo-compounds [PDF]
J. Chem. Soc., Trans., 1907 n ...
openaire +1 more source