Results 31 to 40 of about 6,933 (191)

Copper-Catalyzed Oxyvinylation of Diazo Compounds [PDF]

open access: yesOrganic Letters, 2020
A copper(I)-catalyzed vinylation of diazo compounds with vinylbenziodoxolone reagents (VBX) as partners is reported. The transformation tolerates diverse functionalities on both reagents delivering polyfunctionalized vinylated products. The strategy was successfully extended to a three-component/intermolecular version with alcohols.
Guillaume Pisella   +2 more
openaire   +3 more sources

Enantioselective three-component aminomethylation of α-diazo ketones with alcohols and 1,3,5-triazines

open access: yesNature Communications, 2020
Strategies for enantioselective α-aminomethylation of carbonyl compounds rely on the chiral activation of stable ketones substrate. Here, the authors report a rhodium/chiral phosphoric acid cooperative catalysis for the three-component reaction of α ...
Jiuwei Che   +4 more
doaj   +1 more source

Asymmetric formal C–C bond insertion into aldehydes via copper-catalyzed diyne cyclization

open access: yesNature Communications, 2023
The formal C–C bond insertion into aldehydes is an attractive methodology for the assembly of homologated carbonyl compounds. However, the homologation of aldehydes has been limited to diazo approach and the enantioselective reaction was rarely developed.
Cui-Ting Li   +6 more
doaj   +1 more source

Water‐Compatible SuFEx‐Active Diazonium Linchpin Platform for Rapid Modular Diversification and On‐DNA Functionalization

open access: yesAdvanced Functional Materials, EarlyView.
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong   +5 more
wiley   +1 more source

Traditional and New methods for the Preparation of Diazocarbonyl Compounds

open access: yesAnais da Academia Brasileira de Ciências, 2018
For many years diazocarbonyl compounds have been studied due to their versatility and usability in many chemical transformations. In this review, we summarize the traditional methods to prepare these compounds as well as the new methods and recent ...
ANTONIO C.B. BURTOLOSO   +2 more
doaj   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

open access: yesAdvanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi   +3 more
wiley   +1 more source

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives

open access: yesMolecules, 2021
Synthetic heterocyclic compounds have incredible potential against different diseases; pyridines, phenolic compounds and the derivatives of azo moiety have shown excellent antimicrobial, antiviral, antidiabetic, anti-melanogenic, anti-ulcer, anticancer ...
Tehreem Tahir   +6 more
doaj   +1 more source

Facile and diastereoselective arylation of the privileged 1,4-dihydroisoquinolin-3(2H)-one scaffold

open access: yesBeilstein Journal of Organic Chemistry, 2022
A practically convenient and streamlined protocol for the trans-diastereoselective introduction of an aryl substituent at position 4 of the 1,4-dihydroisoquinol-3-one (1,4-DHIQ) scaffold is presented.
Dmitry Dar’in   +3 more
doaj   +1 more source

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