Results 31 to 40 of about 21,735 (237)

Synthesis of cyclic alpha-diazo-beta-keto sulfoxides in batch and continuous flow [PDF]

, 2017
Diazo transfer to beta–keto sulfoxides to form stable isolable alpha-diazo-beta-keto sulfoxides has been achieved for the first time. Both monocyclic and benzofused ketone derived beta-keto sulfoxides were successfully explored as substrates for diazo ...
Buckley, Naomi M., Collins, Stuart G., Eccles, Kevin S., Lawrence, Simon E., Maguire, Anita R., McCaw, Patrick G.   +5 more
core   +1 more source

Copper-Catalyzed Oxyvinylation of Diazo Compounds [PDF]

Organic Letters, 2020
A copper(I)-catalyzed vinylation of diazo compounds with vinylbenziodoxolone reagents (VBX) as partners is reported. The transformation tolerates diverse functionalities on both reagents delivering polyfunctionalized vinylated products. The strategy was successfully extended to a three-component/intermolecular version with alcohols.
Guillaume Pisella, Alec Gagnebin, Jerome Waser   +2 more
openaire   +2 more sources

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

Angewandte Chemie, EarlyView.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach, Ioanna Tsiara, Wawrzyniec Haberek, Weifeng Lin, Daniel Globisch   +4 more
wiley   +2 more sources

Catalytic Cycloaddition of Diazo Compounds Based on Pharmacologically Significant and Natural Compounds to C₆₀-Fullerene †

Chemistry Proceedings, 2022
The data obtained by the authors in the field of carbon cluster chemistry, namely, the catalytic cycloaddition of diazo compounds of modern pharmacologically significant and natural compounds to C60-fullerene under the action of complex Pd–catalysts, are
Liliya L. Khuzina, Airat R. Tuktarov, Usein M. Dzhemilev   +2 more
doaj   +1 more source

Diazo Transfer From Nitrous Oxide Employing Phosphorus Ylides

Angewandte Chemie, EarlyView.
A phosphorus ylide‐mediated strategy achieves the direct fixation of nitrous oxide (N2O) to access diazo compounds, which after intra‐ or intermolecular trapping, afford N2‐containing organic building blocks. This approach provides an alternative to hazardous diazo‐transfer reagents and establishes N2O fixation as a sustainable methodology.
Jhen‐Kuei Yu, Jan Niclas Ludwig, Patrick Wolf Antoni, David Tymann, Max Martin Hansmann   +4 more
wiley   +2 more sources

The gas phase cyclization of deprotonated N-aryl-2-cyano-2-diazoacetamides [PDF]

, 2005
The document attached has been archived with permission from the publisher.1-Aryl-4-cyano-5-hydroxy-1,2,3-triazoles can be obtained in solution by base-catalysed cyclization of N-aryl-2-cyano-2-diazoacetamides.
Bilusich, D., Blumenthal, T., Bowie, J., Lebedev, A., Lobodin, V., Morzherin, Y., Ovcharenko, V.   +6 more
core   +2 more sources

Azide‐to‐Diazo Transformation Facilitated by Michael Addition via Phosphazide Formation

Angewandte Chemie, EarlyView.
A new type of Michael addition based on azide‐to‐diazo conversion is disclosed. This unusual transformation proceeds via 1,4‐addition accompanied by N─N bond cleavage of phosphazide intermediates under practical conditions. The high versatility of the resulting Michael adducts enables the synthesis of a wide variety of organonitrogen compounds ...
Tomoki Mano, Takahiro Yasuda, Gaku Orimoto, Suguru Yoshida   +3 more
wiley   +2 more sources

λ5-Phosphorus-Containing α-Diazo Compounds (PCDCs): a valuable tool for accessing phosphorus-functionalized molecules [PDF]

, 2016
The compounds characterized by the presence of a λ5-phosphorus functionality at the α-position with respect to the diazo moiety, here referred to as λ5-phosphorus-containing α-diazo compounds (PCDCs), represent a vast class of extremely versatile ...
Marinozzi, Maura, Pertusati, Fabrizio, Serpi, Michaela   +2 more
core   +2 more sources

Synthesis and Antibacterial Activity of bis Heterocyclic Derivatives of 1,3,4-thiadiazole

Iraqi Journal of Pharmaceutical Sciences, 2017
The Chemistry of heterocyclic sulphur and nitrogen containing compounds have a great role in the  field of scientific studies, The 2-amino 5-mercapto-1,3,4-thiadiazole ring for instance, has gained more importance in recent years because  they are ...
Ahlam A. Al-jubouri, Ahlam J. Qasir J. Qasir   +1 more
doaj   +3 more sources

Sulfur‐Directed Construction of Vinyl Cyclopropanes from 1,3‐Dienes

Angewandte Chemie, EarlyView.
Sulfur takes control. A pending thioether acts as a molecular compass, directing carbene addition to the 1,3‐diene scaffold with exceptional regio‑ and diastereocontrol to forge sulfur‐substituted vinyl cyclopropanes (S‐VCPs) — molecular architectures inaccessible via conventional cyclopropanation strategies.
Anna Keimer, Jonas Rettig, Tim‐Niclas Streit, Bob Barthel, Mélissa Calmels, Moritz Malischewski, Franz‐Lucas Haut   +6 more
wiley   +2 more sources