Results 81 to 90 of about 21,735 (237)
A Convenient Synthesis of 14C-Anthralin [PDF]
, 1994 Anthralin [1,8-dihydroxy-9(10H)-anthracenone] is among the most widely used drugs in the topical treatment of psoriasis1). However, not much is known concerning its mode of action at the molecular level, although a variety of cellular targets have been ...
Auterhoff +12 more
core +1 more source
Chemistry – A European Journal, EarlyView.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
Catalytic asymmetric constructions of nitrogen, boron and carbon continuous stereogenic centers
Nature CommunicationsPrecise construction of molecular chirality is a longstanding scientific challenge in synthetic chemistry. Although methods to enantioselectively assemble consecutive carbon stereocenters are abundant, courses to establish enriched continuous ...
Guan Zhang +6 more
doaj +1 more source
Recent advances in asymmetric [2+1] cycloaddition with α-cyano diazo compounds
Tetrahedron ChemThe asymmetric [2 + 1] cycloaddition of α-cyano diazo compounds has emerged as an efficient and versatile strategy for synthesizing cyano-substituted cyclopropanes, which are valuable scaffolds in medicinal chemistry, materials science, and natural ...
Shuicai Chen +5 more
doaj +1 more source
Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy
Chemistry – A European Journal, EarlyView.Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez +3 more
wiley +1 more source
ChemistryEuropeAn in‐depth mechanistic study for the photogeneration of free diazoalkanes from N‐tosylhydrazone precursors by combining observations from synthesis with spectroscopic and theoretical methods is presented.
Ferdinand L. Pointner +12 more
doaj +1 more source
Cycloadditions of cyclohexynes and cyclopentyne. [PDF]
, 2014 We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described.
Garg, Neil K +4 more
core +2 more sources
Chemistry – A European Journal, EarlyView.Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.A series of thirteen (N‐heterocyclic carbene) NHC‐stabilized borenium cations is synthesized from NHC→BH3 complexes via hydroboration and condensation with diols. The novel compounds are fully characterized. Eight crystal structures are presented. Kinetic and NMR data show how the structural features translate to catalytic activity in hydrosilylation ...
Michał Jakubczyk +4 more
wiley +1 more source
Hydrogen Atom Transfer: An Intramolecular Main‐Group Metal‐Ligand Cooperative Biradical Pathway
Chinese Journal of Chemistry, EarlyView.The molecular system consisting of a main‐group metal and a redox‐active ligand, ((2,6‐iPr2C6H3)NC(Me))2AlCl(THF), has been shown to react with azides and diazomethanes, yielding products through both a biradical intermediate and a hydrogen atom transfer process.
Ting Chen +6 more
wiley +1 more source