Results 11 to 20 of about 921 (148)

Light-Driven Ratchet Mechanism Accelerates Regioselective Metal-Cation Exchange in a Heterobimetallic Helicate. [PDF]

Angew Chem Int Ed Engl
Photoswitchable homo‐ and heterobimetallic helicates form with high diastereo‐ and regioselectivity via single‐step self‐assembly or self‐sorting. White‐light exposure autonomously operates one helicate as a molecular ratchet, promoting the selective formation of an out‐of‐equilibrium structure.
Notheis MJ, Schnakenburg G, von Krbek LKS.   +2 more
europepmc   +3 more sources

Light-Controlled Destruction and Assembly: Switching between Two Differently Composed Cage-Type Complexes. [PDF]

Angew Chem Int Ed Engl, 2023
We report on two regioisomeric, diazocine ligands 1 and 2 that can both be photoswitched between the E- and Z-configurations with violet and green light.
Hugenbusch D, Lehr M, von Glasenapp JS, McConnell AJ, Herges R.   +4 more
europepmc   +3 more sources

Real-Time In Situ Imaging of Aggregation-Induced Emission and Solvent-Guided Morphogenesis of a "V-Shaped" 4-Amino-1,8-Naphthalimide Tröger's Base Supramolecular Scaffold. [PDF]

Small Sci
It is demonstrated that the self‐assembly process of the 3‐pyridyl‐based TBNap structure is highly solvent deepened. X‐ray diffraction analysis confirms that the TBNap structure possesses solvent‐depended packing arrangements in the crystalized form.
Shanmugaraju S, Umadevi D, Savyasachi AJ, Hawes CS, Kitchen JA, McManus GJ, Gunnlaugsson T.   +6 more
europepmc   +2 more sources

Photoswitchable Diazocine Derivative for Adenosine A₃ Receptor Activation in Psoriasis. [PDF]

J Am Chem Soc
Altres ajuts: CERCA Programme/Generalitat de CatalunyaIncorporating photoisomerizable moieties within drugs offers the possibility of rapid and reversible light-dependent switching between active and inactive configurations.
López-Cano M, Scortichini M, Tosh DK, Salmaso V, Ko T, Salort G, Filgaira I, Soler C, Trauner D, Hernando J, Jacobson KA, Ciruela F.   +11 more
europepmc   +5 more sources

Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib. [PDF]

Int J Mol Sci, 2020
In this study, we aimed at the application of the concept of photopharmacology to the approved vascular endothelial growth factor receptor (VEGFR)-2 kinase inhibitor axitinib.
Heintze L, Schmidt D, Rodat T, Witt L, Ewert J, Kriegs M, Herges R, Peifer C.   +7 more
europepmc   +3 more sources

Unsymmetrically-Substituted 5,12-dihydrodibenzo[b,f][1,4]diazocine-6,11-dione Scaffold-A Useful Tool for Bioactive Molecules Design. [PDF]

Molecules, 2020
Unsymmetrically N-substituted and N,N’-disubstituted 5,12-dihydrodibenzo [b,f][1,4]diazocine-6,11-diones were synthesized in the new protocol. The desired modifications of the dibenzodiazocine scaffold were introduced at the stages of proper selection of
Bieszczad B, Garbicz D, Trzybiński D, Dudek MK, Woźniak K, Grzesiuk E, Mieczkowski A.   +6 more
europepmc   +3 more sources

Unsymmetrically Substituted Dibenzo[b,f][1,5]-diazocine-6,12(5H,11H)dione-A Convenient Scaffold for Bioactive Molecule Design. [PDF]

Molecules, 2020
A novel approach for the synthesis of unsymmetrically substituted dibenzo[b,f][1,5]diazocine-6,12(5H,11H)diones has been developed. This facile three-step method uses variously substituted 1H-benzo[d][1,3]oxazine-2,4-diones (isatoic anhydrides) and 2 ...
Bieszczad B, Garbicz D, Trzybiński D, Mielecki D, Woźniak K, Grzesiuk E, Mieczkowski A.   +6 more
europepmc   +3 more sources

(±) Methanodibenzodiazocine tethered [C-H]δ+ functional site: Study towards benzoin condensation and Baylis-Hillman reactions [PDF]

, 2015
New heterocyclic ring systems consisting of (±) methanodibenzodiazocine and imidazolium/ benzimidazolium salts were synthesized in very good yield. Subsequently, these halide salts were subjected to the anion exchange reaction with KPF6 to yield ...
Arruri, S, G, Prabusankar
core   +5 more sources

Comparative studies of the Pschorr reaction in the pyrazole series. Access to the new dibenzo(e,g)pyrazolo(1,5-a)(1,3)diazocine system of pharmaceutical interest [PDF]

, 2008
The diazonium tetrafluoroborate 11 obtained from 2-amino-N-methyl-N-(1-phenyl-3-methylpyrazol-5-yl)benzamide was transformed in dry acetonitrile via an ionic or radical pathway. Diferences were observed with respect to ionic or radical transformations in
BOMBIERI, G, CASCIOFERRO, Stella Maria, DAIDONE, Giuseppe, MAGGIO, Benedetta, MENEGHETTI, F, PLESCIA, Salvatore, RAFFA, Demetrio, RAIMONDI, Maria Valeria, SABATINO, Maria Antonietta   +8 more
core   +1 more source

Synthesis and Spectral Characterization of Benzo[6,7] [1,5]diazocino[2,1-a]isoindol-12-(14H)-one Derivatives [PDF]

, 2016
© 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).A simple ...
Bassin, Bhavani Anagani, Christopher Benham, Dufort, Houbion, Jatinder Bassin, Madhu Goyal, Maryam Hashemian, Othman, Ute Gerhard   +9 more
core   +2 more sources