Results 21 to 30 of about 630 (149)
Biological Characterization of Azo- and Diazocine-based Photoswitches [PDF]
, 2022 Die Photopharmakologie verfolgt das Ziel einer gerichteten Therapie mit hoher Raum-Zeit-Auflösung durch Licht-kontrollierte Wirkstoffaktivierung bzw. -schaltung. Damit sollen Nebenwirkungen, Resistenzbildungen und Umwelteinflüsse reduziert werden.
Heintze, Linda
core +1 more source
Molecules, 2016 A simple synthetic route affording 27%–85% yields of benzo[6,7][1,5]diazocino[2,1-a]isoindol-12(14H)-one ring systems from readily available 3-(2-oxo-2-phenylethyl) isobenzofuran-1(3H)-ones and 2-(aminomethyl)aniline starting materials in toluene and ...
Jatinder P. Bassin +5 more
doaj +1 more source
Pharmaceuticals, 2021 Histone deacetylase (HDAC) inhibitors are a class of drugs used in the cancer treatment. Here, we developed a library of 19 analogues of Vorinostat, an HDAC inhibitor used in lymphomas treatment.
Bartosz Bieszczad +7 more
doaj +1 more source
, 2016 The attempted generation of the potentially aromatic 6,7-diphenyldibenzo[e,g][1,4]diazocine dianion from sodium in THF leads with profound rearrangement to the isomeric N-(2-amino-1,2-diphenylethenyl)carbazole dianions and, after hydrolysis, to a 55:45 ...
Renuka N. Manchanayakage (2349841) +2 more
core +3 more sources
Beilstein Journal of Organic Chemistry, 2019 Seven symmetrically 3,3’-substituted diazocines were synthesized. Functional groups include alcohol, azide, amine and vinyl groups, which are suitable for polymer synthesis.
Widukind Moormann +2 more
doaj +1 more source
, 2016 A series of poly(arylene ether sulfone) copolymers containing the diazocine unit (0, 20, 50, 80, 100 mol %) were synthesized via step-growth polymerization.
Timothy E. Long (1428190) +2 more
core +2 more sources
Synthesis of Chiral Diazocine Derivatives via a Copper-Catalyzed Dearomative [5+3] Cycloaddition
, 2022 Copper-catalyzed [5+3] cycloaddition of N-aromatic zwitterions and enol diazoacetates produced enantio-enriched diazocine derivatives. A sterically encumbered BOX ligand and NaBArF additive played significant roles in driving the overall catalytic ...
Eun Jeong Yoo (1617397) +2 more
core +1 more source
Reproductive Mechanisms Influenced by a Diazocine
Experimental Biology and Medicine, 1965 Summary2,8-Dichloro-6,12-diphenyl-dibenzo[b,f][l,5] diazocine completely inhibited pregnancy when administered either orally or subcutaneously to female rats at doses as low as 0.5 mg daily for 7 days at time of mating. At higher doses, single treatments prior to completion of implantation were equally effective.
G W, Duncan, S C, Lyster, J B, Wright
openaire +2 more sources
Acta Crystallographica Section E, 2010 The rings of the three-ring cytisine system in the title compound [systematic name: (1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocine-8-thione], C12H16N2S, have planar [maximum deviation 0.0170 (7) Å ...
Anita M. Owczarzak +2 more
doaj +1 more source
Amino-substituted diazocines as pincer-type photochromic switches
Beilstein Journal of Organic Chemistry, 2013 Azobenzenes are robust, reliable, and easy to synthesize photochromic switches. However, their high conformational flexibility is a disadvantage in machine-like applications. The almost free rotation of the phenyl groups can be restricted by bridging two
Hanno Sell +2 more
doaj +1 more source