Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca2+ and mitoKATP channels [PDF]
, 2018 Whether the response of the fetal heart to ischemia-reperfusion is associated with activation of the c-Jun N-terminal kinase (JNK) pathway is not known.
Bonny, Christophe +4 more
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Anticonvulsant Effect of Diazoxide against Dichlorvos-Induced Seizures in Mice
The Scientific World Journal, 2013 Dichlorvos, a synthetic organophosphate toxin, is used as pesticides. These toxins can be used as pesticides in farming and medicine for the devastation and/or elimination of ectoparasites of animals.
Amin Jazayeri +2 more
doaj +1 more source
Mechanisms of Volatile Anesthetic-Induced Myocardial Protection [PDF]
, 2003 Volatile anesthetics protect myocardium against reversible and irreversible ischemic injury. Experimental evidence from several in vitro and in vivo animal models demonstrates that volatile agents enhance the recovery of stunned myocardium and reduce the
Gu, Weidong +6 more
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Polycystic Ovary Syndrome: Pathogenesis, health consequences, and treatment of PCOS in relation to insulin resistance [PDF]
, 2012 The purpose of this paper is to present a review of the current research on polycystic ovary syndrome (PCOS). PCOS is one of the most common endocrine disorders in women of reproductive age, affecting 5-10% of the population. Despite its prevalence, PCOS
Bernier, Danielle
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Angiotensin II and tumour necrosis factor α as mediators of ATP-dependent potassium channel remodelling in post-infarction heart failure [PDF]
, 2017 Aims Angiotensin II (Ang II) and tumour necrosis factor α (TNFα) are involved in the progression from compensated hypertrophy to heart failure. Here, we test their role in the remodelling of ATP-dependent potassium channel (KATP) in heart failure ...
Baertschi, Alex J. +4 more
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Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart [PDF]
, 2018 We have previously reported in the early septating embryonic heart that electromechanical disturbances induced by anoxia-reoxygenation are distinct in atria, ventricle, and outflow tract, and are attenuated in ventricle by opening of mitochondrial KATP ...
Gardier, Stephany +3 more
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مجله دانشگاه علوم پزشکی گرگان, 2010 Background and Objective: Until now there is no drug formulated to prevent Neuronal Loss following Brain Stroke. In this study, we compared the effects of the mitoKATP opener, diazoxide, on ultra-structural morphology changes following in cortical ...
Katebi M (PhD) +5 more
doaj
JCRPEHomozygous or compound heterozygous mutations in insulin receptor gene (INSR) lead to marked insulin resistance and hyperglycaemia in Donohue syndrome and Rabson-Mendenhall syndrome, conditions which are associated with significant morbidity early in ...
Sarah Wing-Yiu Poon +3 more
doaj +1 more source
Keringő beta-amyloid peptid hatása az agy vérellátására, és a vér-agy gát immunsejtekkel szembeni átjárhatóságára = The effect of circulating beta-amyloid peptide on cerebral blood flow, and blood-brain barrier permeability against immune cells [PDF]
, 2007 Célunk volt megmutatni a keringésbe juttatott -amyloid (A) és tumor nekrózis faktor- (TNF) károsító hatását az agyi vérátáramlásra (CBF) és az agyi mikroerek ultrasrtuktúrájára, igazolni a hipotézist, hogy az A ...
Farkas, Eszter +3 more
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Anaesthetics and cardiac preconditioning. Part I. Signalling and cytoprotective mechanisms [PDF]
, 2017 Cardiac preconditioning represents the most potent and consistently reproducible method of rescuing heart tissue from undergoing irreversible ischaemic damage. Major milestones regarding the elucidation of this phenomenon have been passed in the last two
Lucchinetti, E. +4 more
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