Results 91 to 100 of about 8,944 (181)
Use of diphenylhydantoin and diazoxide to investigate insulin secretory mechanisms
In the isolated, perfused rat pancreas, we contrasted effects of diphenylhydantoin (DPH) and diazoxide on glucose-induced biphasic insulin secretion. Either drug partially inhibited the first phase.
GM Grodsky +3 more
core +1 more source
Background and Objective: Until now there is no drug formulated to prevent Neuronal Loss following Brain Stroke. In this study, we compared the effects of the mitoKATP opener, diazoxide, on ultra-structural morphology changes following in cortical ...
Katebi M (PhD) +5 more
doaj
The Action of Diazoxide on Isolated Vascular Smooth Muscle Electrophysiology and Contraction
Diazoxide inhibits spontaneous motility and contractile responses to noradrenaline, serotonin, or procaine in isolated rabbit anterior mesenteric vein (A.M.V.).
M. C. Sutter, H. James Rhodes
core +1 more source
Homozygous or compound heterozygous mutations in insulin receptor gene (INSR) lead to marked insulin resistance and hyperglycaemia in Donohue syndrome and Rabson-Mendenhall syndrome, conditions which are associated with significant morbidity early in ...
Sarah Wing-Yiu Poon +3 more
doaj +1 more source
Diazoxide attenuates indomethacin-induced small intestinal damage in the rat
ATP-sensitive potassium (K(ATP)) channel openers have been shown to protect against cellular damage in neurons cardiac muscle and kidney and to effectively reduce nonsteroidal anti inflammatory drug (NSAID)-induced gastric damage in rats We investigated ...
POZZOLI, Cristina +11 more
core +1 more source
Diazoxide prevents LPS-induced demyelination in organotypic cerebellar culture.
Cerebellar slices were treated with 15µg/ml LPS to induce demyelination as shown with heavy neurofilament (NFH, red) and myelin basic protein (MBP, green) immunostaining.
Noemí Virgili (457136) +6 more
core +1 more source
Diazoxide-Responsive Congenital Hyperinsulinism in a Preterm Infant With Homozygous <i>ABCC8</i> Mutation: A Case Report. [PDF]
Kansakar P +6 more
europepmc +1 more source
Congenital Hyperinsulinism With Paternally Inherited <i>ABCC8</i> Variants: A Single Center Experience Over a Decade in Singapore. [PDF]
Chua C +4 more
europepmc +1 more source
A Novel <i>ABCC8</i> Variant in an Adult with Hyperinsulinemic Hypoglycemia Suggestive of Congenital Hyperinsulinism: A Case Report. [PDF]
Rabani H +4 more
europepmc +1 more source

