Results 91 to 100 of about 8,944 (181)

Use of diphenylhydantoin and diazoxide to investigate insulin secretory mechanisms

open access: yes, 1975
In the isolated, perfused rat pancreas, we contrasted effects of diphenylhydantoin (DPH) and diazoxide on glucose-induced biphasic insulin secretion. Either drug partially inhibited the first phase.
GM Grodsky   +3 more
core   +1 more source

Effect of Diazoxide on Ultra-structure morphology of Rat parietal cortex after ischemic – reperfusion

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2010
Background and Objective: Until now there is no drug formulated to prevent Neuronal Loss following Brain Stroke. In this study, we compared the effects of the mitoKATP opener, diazoxide, on ultra-structural morphology changes following in cortical ...
Katebi M (PhD)   +5 more
doaj  

The Action of Diazoxide on Isolated Vascular Smooth Muscle Electrophysiology and Contraction

open access: yes, 1971
Diazoxide inhibits spontaneous motility and contractile responses to noradrenaline, serotonin, or procaine in isolated rabbit anterior mesenteric vein (A.M.V.).
M. C. Sutter, H. James Rhodes
core   +1 more source

Diazoxide-unresponsive Hyperinsulinemic Hypoglycaemia in a Preterm Infant with Heterozygous Insulin Receptor Gene Mutation

open access: yesJCRPE
Homozygous or compound heterozygous mutations in insulin receptor gene (INSR) lead to marked insulin resistance and hyperglycaemia in Donohue syndrome and Rabson-Mendenhall syndrome, conditions which are associated with significant morbidity early in ...
Sarah Wing-Yiu Poon   +3 more
doaj   +1 more source

Diazoxide attenuates indomethacin-induced small intestinal damage in the rat

open access: yes, 2011
ATP-sensitive potassium (K(ATP)) channel openers have been shown to protect against cellular damage in neurons cardiac muscle and kidney and to effectively reduce nonsteroidal anti inflammatory drug (NSAID)-induced gastric damage in rats We investigated ...
POZZOLI, Cristina   +11 more
core   +1 more source

Diazoxide prevents LPS-induced demyelination in organotypic cerebellar culture.

open access: yes, 2013
Cerebellar slices were treated with 15µg/ml LPS to induce demyelination as shown with heavy neurofilament (NFH, red) and myelin basic protein (MBP, green) immunostaining.
Noemí Virgili (457136)   +6 more
core   +1 more source

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