Natural Dibenzo-α-Pyrones and Their Bioactivities [PDF]
Natural dibenzo-α-pyrones are an important group of metabolites derived from fungi, mycobionts, plants and animal feces. They exhibit a variety of biological activities such as toxicity on human and animals, phytotoxicity as well as cytotoxic ...
Ziling Mao, Weibo Sun, Daowan Lai
exaly +8 more sources
Natural Dibenzo-α-Pyrones: Friends or Foes? [PDF]
Natural dibenzo-α-pyrones (DAPs) can be viewed from two opposite angles. From one angle, the gastrointestinal metabolites urolithins are regarded as beneficial, while from the other, the emerging mycotoxin alternariol and related fungal metabolites are ...
Georg Aichinger
exaly +4 more sources
Bioactive α-Pyrone Derivatives from the Endophytic Fungus Diaporthe sp. CB10100 as Inducible Nitric Oxide Synthase Inhibitors [PDF]
Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially used in many indications, such as rheumatoid arthritis, pain, and ...
Hong Pu +15 more
doaj +2 more sources
Combinatory Exposure to Urolithin A, Alternariol, and Deoxynivalenol Affects Colon Cancer Metabolism and Epithelial Barrier Integrity in vitro [PDF]
The human gastrointestinal tract is an important site of nutrient absorption and a crucial barrier against xenobiotics. It regularly faces “chemical cocktails” composed of food constituents, their human and microbial metabolites, and foodborne ...
Julia Groestlinger +5 more
doaj +2 more sources
Pd/C was found to be an efficient and convenient metal catalyst for intramolecular C–H arylation reactions in the synthesis of phenanthridinones and dibenzo-α-pyrones. A variety of phenanthridinones and dibenzo-α-pyrones were synthesized under the highly
Lingyu Zhao +4 more
exaly +3 more sources
ANALGESIC ACTIVITY OF SOME NEW SYNTHETIC DIBENZO-α-PYRONES DERIVATIVES
Following standard Hurtley reaction, by using 2 - Bromobenzoic acid, resorcinol and NaOH in the presence of CuSO 4 solution as a catalyst, a clay coloured solid of dibenzo - α - pyrone was prepared. This resulting solid of DBαP was then reacted with various amines respectively, formaldehyde and ethanol and refluxed for 1.5 h as per Mannich reaction ...
Birendra Shrivastava
exaly +2 more sources
Secondary metabolites of Alternaria: A comprehensive review of chemical diversity and pharmacological properties. [PDF]
Fungi are considered to be one of the wealthiest sources of bio-metabolites that can be employed for yielding novel biomedical agents. Alternaria, including parasitic, saprophytic, and endophytic species, is a kind of dark fungi that can produce a broad ...
Zhao S +9 more
europepmc +3 more sources
Natural resorcylic lactones derived from alternariol. [PDF]
In this overview, naturally occurring resorcylic lactones biosynthetically derived from alternariol and almost exclusively produced by fungi, are discussed with view on their isolation, structure, biological activities, biosynthesis, and total ...
Podlech J.
europepmc +3 more sources
Characterization of alternaria species associated with heart rot of pomegranate fruit [PDF]
This study was aimed at identifying Alternaria species associated with heart rot disease of pomegranate fruit in southern Italy and characterizing their mycotoxigenic profile. A total of 42 Alternaria isolates were characterized.
Aloi F. +8 more
core +5 more sources
Phytochemical And Pharmacognostic Insights Into Shilajatu (Asphaltum Punjabianum): Types, Purification, And Standardization Approaches [PDF]
Shilajatu, also known as Asphaltum Punjabianum, is a well-known Rasayana (rejuvenative) ingredient in Ayurveda, with numerous therapeutic applications for enhancing energy, longevity, and metabolic health.
Gupta, Dr. Parameswarappa S. Byadgi, Prof. Neeraj Kumar, Jyoti Shah, Dhananjay Kumar, Dr. Laxmi Narayan
core +2 more sources

