Results 11 to 20 of about 283 (127)
Total Syntheses of Sappanin-Based Natural Products Enabled by Pattern Recognition Analysis and Brominative Aromatization. [PDF]
A unified synthetic strategy enables the total syntheses of sappanin‐based natural products from a common privileged intermediate derived from cyclic vinylogous esters. Abstract Described is a concise route to caesappins A and B, urolithin C, and protosappanin A, which share a common sappanin core.
Zhao WT, Liang JY, Wu YK.
europepmc +2 more sources
Emerging Fusarium and Alternaria mycotoxins : occurrence, toxicity and toxicokinetics [PDF]
Emerging Fusarium and Alternaria mycotoxins gain more and more interest due to their frequent contamination of food and feed, although in vivo toxicity and toxicokinetic data are limited.
Antonissen, Gunther +3 more
core +6 more sources
Abstract Cancer metastasis remains the most common cause of death in breast cancer patients. Tumor‐associated macrophages (TAMs) are a novel therapeutic target for the treatment of metastatic breast cancer. Despite the good anti‐cancer activity of garcinone E (GE), there are no reports on its therapeutic effects on breast cancer metastasis.
Xin Nie +12 more
wiley +1 more source
Natural dietary products targeting the MQC network as antiaging agents for different types of muscle. Abstract Mitochondria are the main sources of energy production for muscle tissues, including skeletal, cardiac, or smooth muscle, to support their activities. Mitochondrial dysfunction and dysregulation of their quality control systems are significant
Qi Chen +4 more
wiley +1 more source
An updated overview of anticancer effects of alternariol and its derivatives: Underlying molecular mechanisms [PDF]
Alternariol is a toxic metabolite of Alternaria fungi and studies have shown multiple potential pharmacological effects. To outline the anticancer effects and mechanisms of alternariol and its derivatives based on database reports, an updated search of ...
Ahmad Faizal Abdull Razis +10 more
core +2 more sources
A physiologically‐based pharmacokinetic model for urolithin A that includes uptake, metabolism and dissolution kinetics is constructed. It is evaluated against human data and then used to predict plasma and tissue concentrations of UA and its glucuronides.
Georg Aichinger +3 more
wiley +1 more source
Oxidative N‐Heterocyclic Carbene Catalysis
The advances in oxidative N‐heterocyclic carbene (NHC)‐catalysis are reviewed according to the strategies that rely on typical NHC‐bound intermediates, including acyl/imidoyl azolium, α,β‐unsaturated acyl azolium, and azolium peroxide species, as well as NHC‐derived ortho‐quinone methide (o‐QM), aza‐fulvene, and triaza‐diene intermediates, with ...
Carmela De Risi +5 more
wiley +1 more source
Xanthones and Xanthone O‐β‐D‐Glucosides from the Roots of Polygala azizsancarii Dönmez
Abstract Nine xanthone derivatives (1–9) were isolated from the roots of Polygala azizsancarii, which is a narrow endemic species for the flora of Türkiye. Based on all of the evidence, the structures of 1–9 were established as two previously undescribed xanthone O‐glucosides, 3‐O‐β‐D‐glucopyranosyloxy‐1,6‐dihydroxy‐2,5,7‐trimethoxyxanthone (1), 3‐O‐β ...
İhsan Çalış +6 more
wiley +1 more source
Humic acid from Shilajit – a physico-chemical and spectroscopic characterization [PDF]
Shilajit is a blackish–brown exudation, consisting of organic substances, metal ions and minerals, from different formations, commonly found in the Himalayan region (1000–3000 m) from Nepal to Kashmir.
ASGAR ALI +4 more
core +1 more source
Persistence of the antagonistic effects of a natural mixture of Alternaria mycotoxins on the estrogen-like activity of human feces after anaerobic incubation [PDF]
Several Alternaria mycotoxins are believed to act as endocrine disruptive chemicals (EDCs), since they are reported to bind estrogen receptors in several experimental models.
Aichinger, Georg +8 more
core +1 more source

