Results 1 to 10 of about 288 (74)
Inhibition of mammalian RNA polymerase by 5,6-dichlororibofuranosylbenzimidazole (DRB) and DRB triphosphate [PDF]
Nucleic Acids Research, 1978 DRB triphosphate inhibits activity of isolated RNA polymerase B, and, to a lesser extent, that of polymerase A. The same holds true for transcription in isolated nuclei. It does not act as an initiation inhibitor. In all cases, high concentrations of DRB triphosphate are required. Cells do not phosphorylate DRB to a measurable extent.
C, Dreyer, P, Hausen
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European Journal of Biochemistry, 1982 The effect of nucleoside analogue 5.6‐dichloro‐l‐β‐D‐ribofuranosylbenzimidazole on RNA transcription has been reinvestigated after the observation that explanted salivary gland cells of Chironomus tentans efficiently take up of exogeneous ATP in an undegraded form.
E, Egyházi, A, Pigon, L, Rydlander
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European Journal of Biochemistry, 1983 The question of whether or not the monophosphate metabolites DRB2′P and DRB5′P of the transcription inhibitor 5,6‐dichloro‐1‐β‐d‐ribofuranosylbenzimidazole (DRB) constitute the active form of the inhibitor was investigated in intact salivary gland cells of Chironomus tentants.
E, Egyházi, M, Holst, U, Tayip
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5,6‐dichlororibofuranosylbenzimidazole (DRB) is phosphorylated in salivary gland cells of Chironomus tentans [PDF]
FEBS Letters, 1979 Egyházi, Endre, Shugar, David
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Understanding the functionality of transcript diversity [PDF]
, 2007 Recent years have seen a huge increase in the amount of genomic DNA being sequenced from a wide variety of organisms, giving us an unprecedented insight into the molecular diversity seen in nature.
Harrington, Eoghan
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Interactions of AMPAR-Adenosine Receptor-Equilibrative Nucleoside Transporter in the Hippocampus: Implication for Stroke [PDF]
, 2020 The activation of presynaptic adenosine A1 receptors (A1Rs) is known to cause profound synaptic depression during hypoxia/cerebral ischemic insults, but postsynaptic function of A1Rs are still unclear.
Chen, Zhicheng 1981-
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Androgen receptor-mediated growth suppression and apoptosis of human prostate epithelial cells [PDF]
, 2016 Androgen receptor (AR) signaling is crucial to the development, growth, and homeostasis of the prostate gland, and its dysregulation mediates common prostate pathologies, including benign and malignant forms of neoplasia.
Chen, Congcong
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The Au-Rich Element mRNA Decay-Promoting Activity Of BRF1 Is Regulated By Mitogen-Activated Protein Kinase Activated Protein Kinase 2 [PDF]
, 2008 Regulated mRNA decay is a highly important process for the tight control of gene expression. Inherently unstable mRNAs contain AU-rich elements (AREs) in the 3’ untranslated regions that direct rapid mRNA decay by interaction with decay-promoting ARE ...
Maitra, Sushmit
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Expression and subcellular localisation of poly(A)-binding proteins [PDF]
, 2010 Poly(A)-binding proteins (PABPs) are important regulators of mRNA translation and stability. In mammals four cytoplasmic PABPs with a similar domain structure have been described - PABP1, tPABP, PABP4 and ePABP.
Burgess, Hannah
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