Bazı 2-sübstitüe-5,6-dikloro-1h-benzimidazol bileşiklerinin sentezleri, yapı aydınlatmaları toksisitesi ve antikanser etkisinin incelenmesi üzerine çalışmalar [PDF]
Tez (yüksek lisans) - Anadolu ÜniversitesiAnadolu Üniversitesi, Sağlık Bilimleri Enstitüsü, Farmasötik Kimya Anabilim DalıKayıt no: 154102Bu tezde, ana yapıolarak 5,6-dikloro-1H-benzimidazol çekirdeğini içeren toplam 14 adet bileşik sentez edilmiştir. Bu
Karabajak, Mohammad
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Untersuchungen zur Bedeutung des Kern-Zytoplasma Transports für die biologische Funktion zellulärer Proteine [PDF]
The thesis entitled „Investigations on the significance of nucleo-cytoplasmic transport for the biological function of cellular proteins" aimed to unreveal molecular mechanisms in order to improve our understanding of the impact of nucleo-cytoplasmic ...
Knauer, Shirley
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Murine double minute clone 2 oncoprotein (MDM2) is a key component in the regulation of the tumour suppressor p53. MDM2 mediates the ubiqutination of p53 in the capacity of an E3 ligase and targets p53 for rapid degradation by the proteasome.
Dumaz, Nicolas +5 more
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Growth hormone regulates AT-1a angiotensin receptors in astrocytes
The hypothesis, based on previous in vivo data, that angiotensin AT1 receptors are regulated by GH or insulin-like growth factor I (IGF-I) has been investigated in this study using primary cultures of rat astrocytes as a model of AT1 receptor expression.
Sernia C., Wyse B.
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Udgivelsesdato: 2001-Apr-15Murine double minute clone 2 oncoprotein (MDM2) is a key component in the regulation of the tumour suppressor p53. MDM2 mediates the ubiqutination of p53 in the capacity of an E3 ligase and targets p53 for rapid degradation by ...
Hjerrild, M +5 more
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Regulation of hippocampal synaptic transmission and receptor trafficking by adenosine in hypoxia and ischemia: role of protein phosphatases 1, 2A and 2B, casein kinase 2 (CK2), and equilibrative nucleoside transporters (ENTs). [PDF]
The role of adenosine as an endogenous neuromodulator is well established, but the mechanism(s) mediating the extensive modulatory and regulatory actions of adenosine have not yet been fully elucidated.
Stockwell, Jocelyn
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Regulation of adenosine transporter and AMPA receptor subunit localization by protein kinase CK2 in rat hippocampus [PDF]
The control of extracellular adenosine is crucial to the regulation of synaptic transmission and neuroprotection. Equilibrative nucleoside transporters (ENTs) are highly expressed in the hippocampus and widely accepted as critical regulators of adenosine
Longmuir, Nicole
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The interferon system in the developing mouse embryo and in differentiating teratocarcinoma cells [PDF]
A modified assay to detect interferon production from individual cells has been designed which is more accurate than those already described. Use of this modified assay has demonstrated that the difference between cell lines that can be induced to ...
Barlow, Denise P.
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Fonctions du long ARN non-codant MALAT1 dans la réponse à l'hypoxie [PDF]
Le gène metastasis-associated lung adenocarcinoma transcript 1, ou MALAT1 code pour un long ARN non codant (lncRNA) dont la maturation aboutit à la formation de Malat1 nucléaire et d'un petit ARN non codant cytoplasmique, le MASCRNA.
Sallé, Sandrine
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Transcription and protein synthesis are necessary for androgen-sensitized apoptosis of HPr-1AR.
(A) Cells were treated with 1 nM DHT or vehicle control in the absence or presence of transcription inhibitor, 20 in the5,6-dichlororibofuranosylbenzimidazole (DRB), for 16 hours, and then these cells were co-treated with 1 μM STS or vehicle control for ...
Congcong Chen (796149) +2 more
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