Efficacy of Diclazuril against Eimeria dispersa in Turkeys
Avian Diseases, 1991Diclazuril, a new anticoccidial drug, was tested for its efficacy against Eimeria dispersa in turkeys. A dose-titration study indicated that diclazuril at dosages of 0.5, 1, and 2 ppm in the feed was highly effective in terms of weight gain and suppression of lesions, abnormal droppings, and oocyst shedding.
O, Vanparijs, L, Hermans, R, Marsboom
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HPLC semi‐preparative separation of diclazuril enantiomers and racemization in solution
Journal of Separation Science, 2020AbstractDiclazuril has been widely used in poultry feed for prevention and treatment of coccidiosis, and its chiral separation is rarely reported. Herein, semi‐preparative separation method of diclazuril enantiomers has been developed through normal‐phase high‐performance liquid chromatography.
Jun Fan, MeiYu Zhang, Limin He
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Efficacy of diclazuril in the control of intestinal coccidiosis in rabbits
Veterinary Parasitology, 1989The anticoccidial efficacy of diclazuril was studied in rabbits artificially infected with Eimeria flavescens, Eimeria intestinalis, Eimeria magna and Eimeria perforans. Continuous administration at 1 and 2 ppm in pelleted feed proved to be highly efficacious in controlling oocyst output and faecal scores.
O, Vanparijs, L, Desplenter, R, Marsboom
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Determination of diclazuril in animal feed by liquid chromatography
Journal of Chromatography A, 1992A method is described for the determination of diclazuril (Janssen Research Compound R64433; trademark Clinacox) in chicken feed at the mg kg(-1) level. Compound R062646, a structure analogous to diclazuril, was used as the interna standard. The drug was extracted from food with acidified methanol.
J, De Kock, M, De Smet, R, Sneyers
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Measurement of the Solubility of Diclazuril and Discussion of the Effect of the Cosolvent
Journal of Chemical & Engineering Data, 2019In this research, the solid–liquid equilibrium solubility of diclazuril was measured by the isothermal saturation method, and the influence of the solvent effect on solubility was discussed. In monosolvents, at the determined temperature, the solubility values of diclazuril decrease according to the order: dimethylformamide (DMF) > acetone ...
Shasha Li, Fan Yin, Dechao Rui
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Efficacy of diclazuril in the prevention and cure of intestinal and hepatic coccidiosis in rabbits
Veterinary Parasitology, 1989The efficacy of diclazuril against intestinal and hepatic coccidiosis was studied in artificially infected rabbits. Prophylaxis against intestinal coccidiosis was evaluated using a mixed infection of Eimeria intestinalis, Eimeria magna and Eimeria perforans. Continuous medication in the feed at 1 p.p.m.
O, Vanparijs +3 more
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Efficacy of Diclazuril against Turkey Coccidiosis in a Floor-Pen Experiment
Avian Diseases, 1989Diclazuril, a new anticoccidial drug, was tested for its efficacy in turkeys against mixed Eimeria infections. A floor-pen trial indicated that diclazuril at dosages of 0.5 ppm and 1 ppm in the feed was highly effective against the major pathogenic species E. adenoeides, E. gallopavonis, and E.
O, Vanparijs, L, Hermans, R, Marsboom
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Efficacy of Diclazuril against Turkey Coccidiosis in Dose-Titration Studies
Avian Diseases, 1989Diclazuril, a new anticoccidial drug, was tested for its efficacy in turkeys against single Eimeria infections. Dose-titration studies indicated that diclazuril at dosages of 0.1, 0.5, 1, and 2 ppm was highly effective against the major pathogenic species-E. adenoeides, E. gallopavonis, and E.
O, Vanparijs +3 more
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Activity of diclazuril against Toxoplasma gondii in cultured cells and mice
American Journal of Veterinary Research, 1994Summary The capability of diclazuril, a benzeneacetonitrile anticoccidial agent, to inhibit development of tachyzoites of Toxoplasma gondii was examined in cultured human foreskin fibroblast cells and in Hsd:ICR mice. Treatment of infected cell cultures with 10.0, 1.0, 0.1 or 0.01 μg of diclazuril/ml for 3 days resulted in > 99% reduction in ...
D S, Lindsay, B L, Blagburn
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Control strategies using diclazuril against coccidiosis in goat kids
Parasitology Research, 2011Coccidiosis is probably the main parasitic disease affecting goat kids around the weaning period, leading to high economic losses in goat production due to deaths and delayed growth rates of infected animals. A total of 101 kids of 2-4 weeks of age, naturally infected with Eimeria spp., were divided into five groups and studies were conducted to ...
Ruiz Reyes, Antonio +11 more
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