Results 91 to 100 of about 34,990 (204)

Clinical efficacy and safety of Flamidase in the treatment of lumbar pain: results of a multicenter observational comparative study in Ukraine

open access: yesMedičnì Perspektivi
Pain in the lumbar region (lumbalgia) is one of the leading causes of temporary disability among the economically active population worldwide, including Ukraine.
N.M. Kononenko   +3 more
doaj   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

open access: yesFlavour and Fragrance Journal, Volume 41, Issue 4, Page 841-858, July 2026.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique   +6 more
wiley   +1 more source

Employing diclofenac sodium as a novel therapeutic frontier for Staphylococcus epidermidis infections

open access: yesScientific Reports
The spread of biofilm-forming multidrug-resistant pathogenic bacteria is an alarming public health issue requiring significant research. Drug repurposing is a novel approach to combating bacterial infections that is currently being studied.
Amal M. Abo-Kamar   +4 more
doaj   +1 more source

Visualization of Epidermal Reservoir Formation from Topical Diclofenac Gels by Raman Spectroscopy

open access: yesJournal of Pain Research, 2020
Qihong Zhang,1 Carol R Flach,1 Richard Mendelsohn,1 Leanne Page,2 Susan Whitson,2 Mila Boncheva Bettex3 1Department of Chemistry, Rutgers University, Newark, NJ 07102, USA; 2Charles River Laboratories Edinburgh Ltd., Tranent, East Lothian, UK; 3GSK ...
Zhang Q   +5 more
doaj  

Phytochemical Composition and Potential Bioactivity With ADMET Analysis of Selected Species From Myrtaceae Family

open access: yesFlavour and Fragrance Journal, Volume 41, Issue 4, Page 1002-1029, July 2026.
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi   +8 more
wiley   +1 more source

Environmentally Friendly Lubricants: The Role of Biopolymers in Modern Tribology

open access: yesSPE Polymers, Volume 7, Issue 3, July 2026.
Biomass‐derived biopolymers modified for green tribology applications with reduced friction, wear, and environmental footprint. ABSTRACT Energy losses due to friction and wear are a major challenge for the energy efficiency and sustainability of mechanical systems, motivating the development of green tribology strategies.
Zineb Chiki   +6 more
wiley   +1 more source

Regulated versus unregulated competition: How drug shortages boost illegal pharmacy sales

open access: yesStrategic Management Journal, Volume 47, Issue 7, Page 1811-1839, July 2026.
Abstract Research Summary This study examines how product shortages among legal firms create competitive opportunities for illegal firms. We analyze 713 drug shortages in the United States between 2017 and 2023 and show that shortages substantially increase illicit pharmacies’ sales of affected drugs, which rise by 40.5% during shortages and remain 32 ...
Luis Diestre, Benjamin Barber IV
wiley   +1 more source

Diagnostic Impact of Liver Biopsy Among Antinuclear Antibody Positive Individuals With Mild Liver Enzyme Elevation

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 1, Page 103-111, July 2026.
In ANA‐positive patients with suspected autoimmune hepatitis (AIH), liver biopsy rarely altered therapeutic management when alanine aminotransferase (ALT) was below 101 U/L and cirrhosis was absent. These findings suggest that biopsy may be safely deferred in this low‐risk group.
David Mehdi Asgher Niazi   +8 more
wiley   +1 more source

Stimuli‐Responsive Crosslinked Chitosan/PVP/PEG Hydrogel Networks for Targeted Drug Delivery and Antimicrobial Performance

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT In this study, a unique pH‐sensitive PEG/C/PVA hydrogel based on chitosan (C), polyvinyl propylene (PVP) and polyethylenglycol (PEG) crosslinked with tetraethyl orthosilicate (TEOS) was fabricated. This PEG/C/PVA hydrogel was designed to deliver different drugs with distinct release profiles, including diclofenac sodium and ciprofloxacin, and ...
Danial Mazhar   +4 more
wiley   +1 more source

Ultrasound‐Guided Nerve Hydrodissection for Sural Nerve Injury: A Case Report and Review of the Literature

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Sural nerve entrapment is a relatively uncommon cause of lateral ankle and foot pain and sensory disturbance. Conventional management generally lacks direct, targeted intervention at the site of nerve injury. We report a case of a 33‐year‐old male patient who developed sural neuropathy secondary to a right ankle sprain. Diagnosis was confirmed
Mengshan Zhu   +8 more
wiley   +1 more source

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