Results 171 to 180 of about 595,180 (213)
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Diclofenac Sodium Injection (Dyloject®)
Drugs, 2008*A new formulation of the nonselective NSAID diclofenac sodium suitable for intravenous bolus injection has been developed using hydroxypropyl beta-cyclodextrin as a solubility enhancer (HPbetaCD diclofenac). * HPbetaCD diclofenac intravenous bolus injection was shown to be bioequivalent to the existing parenteral formulation of diclofenac containing ...
Paul L, McCormack, Lesley J, Scott
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Drugs, 1988
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) advocated for use in painful and inflammatory rheumatic and certain non-rheumatic conditions. It is available in a number of administration forms which can be given orally, rectally or intramuscularly.
P A, Todd, E M, Sorkin
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Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) advocated for use in painful and inflammatory rheumatic and certain non-rheumatic conditions. It is available in a number of administration forms which can be given orally, rectally or intramuscularly.
P A, Todd, E M, Sorkin
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Clinical pharmacy, 1989
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage of diclofenac sodium are reviewed. Diclofenac, the first nonsteroidal anti-inflammatory agent (NSAID) to be approved that is a phenylacetic acid derivative, competes with arachidonic acid for binding to cyclo-oxygenase, resulting in decreased formation of prostaglandins.
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The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage of diclofenac sodium are reviewed. Diclofenac, the first nonsteroidal anti-inflammatory agent (NSAID) to be approved that is a phenylacetic acid derivative, competes with arachidonic acid for binding to cyclo-oxygenase, resulting in decreased formation of prostaglandins.
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Diclofenac Sodium in the Treatment of Osteoarthritis
Aging Health, 2006Diclofenac is a well-tolerated, traditional nonsteroidal anti-inflammatory drug that has been shown to be very effective for the treatment of osteoarthritis. Serendipitously, diclofenac has been shown to be relatively selective for cyclooxygenase-2; perhaps due to that fact, it has proven to be well tolerated.
Gina Rohekar, Arthur AM Bookman
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Die Pharmazie, 1989
The crystal structure of the hydrate of the antiphlogistic drug diclofenac sodium was determined to explain the unusual dissolution behaviour in ethyl acetate. The compound crystallizes in the monoclinic space group P2(1)/m with a = 9.464(2), b = 39.405(7), c = 9.972(3) A und beta = 90.74(2) degrees.
G, Reck, G, Faust, G, Dietz
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The crystal structure of the hydrate of the antiphlogistic drug diclofenac sodium was determined to explain the unusual dissolution behaviour in ethyl acetate. The compound crystallizes in the monoclinic space group P2(1)/m with a = 9.464(2), b = 39.405(7), c = 9.972(3) A und beta = 90.74(2) degrees.
G, Reck, G, Faust, G, Dietz
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Journal of Toxicology: Cutaneous and Ocular Toxicology, 1993
William D. Noonan, John R. Samples
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William D. Noonan, John R. Samples
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[Cytotoxic effects of diclofenac sodium].
Nippon Ganka Gakkai zasshi, 1993The authors studied the cytotoxic effect of diclofenac sodium, a prostaglandin synthetic inhibitor, on Chang's cultured human conjunctival cells. Diclofenac sodium inhibited cell growth dose-dependently. Although cell growth was interrupted 12 hrs later by one minute of exposure to a 0.1% solution of diclofenac sodium, the cells began to grow again 24 ...
N, Takahashi +4 more
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The pharmacology of diclofenac sodium (Voltarol).
Rheumatology and rehabilitation, 1980Diclofenac is a potent anti-inflammatory and analgesic compound with good antipyretic and uricosuric properties. It is one of the most potent inhibitors of prostaglandin synthetase known. It shows a favourable therapeutic ratio considering its efficacy, and proved superior to the reference drugs in terms of gastro-intestinal tolerability.
R, Maier +5 more
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