Results 181 to 190 of about 21,122 (233)

Analysis of diclofenac sodium and derivatives

Journal of Pharmaceutical and Biomedical Analysis, 1999
There are two reasons explaining why several researchers have carried out the in vitro release studies of diclofenac sodium (DFNa) using pH media of above 6.5. Firstly the pH dependence of solubility, and secondly the intramolecular cyclization suffered under acidic conditions which causes the salt to become inactivated. Nevertheless, many commercially
M E, Palomo, M P, Ballesteros, P, Frutos
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Pharmacology of diclofenac sodium (Voltaren®)

Seminars in Arthritis and Rheumatism, 1985
HE treatment of inflammatory conditions and rheumatic disorders is largely based on the use of nonsteroidal, anti-inflammatory agents. The choice of the appropriate drug, among a considerable number of compounds, depends ultimately on therapeutic efficacy and tolerability/safety profiles as observed under clinical conditions.
D W, Scholer, I, Boettcher, E C, Ku, A, Schweizer   +3 more
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Diclofenac Sodium and Bruising

Annals of Internal Medicine, 1990
Excerpt To the Editor:No reports to date have described prolonged bleeding time and spontaneous bruising with the use of diclofenac sodium.
Uri Khazan, Mary Toth, Anand Mutgi
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Comparative bioavailability of diclofenac hydroxyethylpyrrolidine vs diclofenac sodium in man

European Journal of Clinical Pharmacology, 1990
A phamacokinetic study in man has been made of a new dosage form of diclofenac hydroxyethylpyrrolidine (DIEP); soluble salt packed in sachets was compared with diclofenac sodium as enteric coated tablets. Oral DIEP 2 X 50 mg showed a significant difference in absorption kinetics (ka, lag time and tmax) as compared to oral diclofenac sodium 2 X 50 mg. A
C A, Maggi, P, Lualdi, G, Mautone
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Spectrophotometric determination of diclofenac sodium in tablets

Journal of Pharmaceutical and Biomedical Analysis, 1991
Simple spectrophotometric methods are described for the determination of diclofenac. In the first method diclofenac reduces iron(III) to iron(II) when heated in aqueous solution. The ferrous ions produced react with 2,2'-bipyridine to form a complex having a maximum absorbance at 520 nm.
Y K, Agrawal, K, Shivramchandra
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Effect of sodium diclofenac on the bioavailability of amoxicillin

International Journal of Antimicrobial Agents, 2006
The aim of this study was to evaluate the effect of sodium diclofenac on the bioavailability of amoxicillin. In this randomised, crossover study with a 1-week washout period, 20 volunteers received a 2g oral dose of amoxicillin (Amoxil) (Group 1) or a 2g oral dose of amoxicillin with 100 mg of sodium diclofenac (Voltaren) (Group 2).
Cristiane, de Cássia Bergamaschi, Rogério Heládio Lopes, Motta, Gilson Cesar Nobre, Franco, Karina, Cogo, Michele Franz, Montan, Glaúcia Maria Bovi, Ambrosano, Pedro Luiz, Rosalen, Fernando de Sá, Del Fiol, Francisco Carlos, Groppo   +8 more
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Treatment of primary dysmenorrhea with diclofenac sodium

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1981
The efficacy of diclofenac sodium was investigated in the painful symptoms of primary dysmenorrhea and in reducing menstrual bleeding. Thirty-five nulliparous women (17-28 yr of age) were included in a double-blind cross-over study for four menstrual periods, two periods with diclofenac sodium and two periods with placebo.
P, Riihiluoma, E, Wuolijoki, M O, Pulkkinen   +2 more
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The Effect of Diclofenac Sodium on Renal Function

Scandinavian Journal of Urology and Nephrology, 1989
The effects of diclofenac sodium on the kidneys were studied during 4 1/2 hours in eight patients with normal renal function. Urinary output decreased within 10 min after the injection, and maximally by 80%. The renal plasma flow and the glomerular filtration rate initially diminished significantly, by 35%, but began to increase after only 2 hours. The
A C, Kinn, J, Elbarouni, P, Seideman, A, Sollevi   +3 more
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Pharmacokinetics of diclofenac sodium injection in swine

Polish Journal of Veterinary Sciences, 2019
The pharmacokinetics of a diclofenac sodium was investigated in swine. A single intravenous (i.v.) or intramuscular (i.m.) injection of 5% diclofenac sodium (concentration = 2.5 mg · kg-1) was administered to 8 healthy pigs according to a two-period crossover design. The pharmacokinetic parameters were calculated by non-compartmental analysis with DAS2.
H F, Yang, Y J, Li, Y Y, Li, C, Huang, L X, Huang, S J, Bu   +5 more
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Nanostructured Diclofenac Sodium Releasing Material

AIP Conference Proceedings, 2008
Various techniques have been developed to produce second generation biomaterials for tissue repair. These include extrusion, molding, salt leaching, spinning etc, but success in regenerating tissues has been limited. It is important to develop porous material, yet with a fibrous structure for it to be biomimetic.
L. Nikkola, K. Vapalahti, A. Harlin, J. Seppälä, N. Ashammakhi, Glaucio H. Paulino, Marek-Jerzy Pindera, Robert H. Dodds, Fernando A. Rochinha, Eshan Dave, Linfeng Chen   +10 more
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