Results 91 to 100 of about 38,088 (249)

Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum.

open access: yesPLoS Genetics, 2009
Organisms like Dictyostelium discoideum, often referred to as DNA damage "extremophiles", can survive exposure to extremely high doses of radiation and DNA crosslinking agents. These agents form highly toxic DNA crosslinks that cause extensive DNA damage.
Xiao-Yin Zhang   +5 more
doaj   +1 more source

Dictyostelium [PDF]

open access: yesCurrent Biology, 2010
Fets, Louise   +2 more
openaire   +2 more sources

Optimization of a large-scale gene disruption protocol in Dictyostelium and analysis of conserved genes of unknown function

open access: yesBMC Microbiology, 2006
Background Development of the post-genomic age in Dictyostelium will require the existence of rapid and reliable methods to disrupt genes that would allow the analysis of entire gene families and perhaps the possibility to undertake the complete knock ...
Escalante Ricardo   +2 more
doaj   +1 more source

Mechanism of Human PTEN Localization Revealed by Heterologous Expression in Dictyostelium

open access: yesOncogene, 2013
Phosphatase and tensin homolog (PTEN) is one of the most frequently mutated tumor suppressor genes in cancers. PTEN has a central role in phosphatidylinositol (3,4,5)-trisphosphate (PIP3) signaling and converts PIP3 to phosphatidylinositol (4,5 ...
Hoai-Nghia Nguyen   +5 more
semanticscholar   +1 more source

Data on the expression and purification of Sestrin protein from Dictyostelium discoideum

open access: yesData in Brief, 2019
The data present here is related to the research article entitled “Sestrin-like protein from Dictyostelium discoideum is involved in autophagy under starvation stress” [1].
S. Rafia, S. Saran
doaj   +1 more source

The green tea catechin epigallocatechin gallate (EGCG) blocks cell motility, chemotaxis and development in Dictyostelium discoideum.

open access: yesPLoS ONE, 2013
Catechins, flavanols found at high levels in green tea, have received significant attention due to their potential health benefits related to cancer, autoimmunity and metabolic disease, but little is known about the mechanisms by which these compounds ...
Kyle J McQuade   +4 more
doaj   +1 more source

Fat-containing cells are eliminated during Dictyostelium development

open access: yesBiology Open, 2017
Triacylglycerol is a universal storage molecule for metabolic energy in living organisms. However, Dictyostelium amoebae, that have accumulated storage fat from added fatty acids do not progress through the starvation period preceding the development of ...
Jessica M. Kornke, Markus Maniak
doaj   +1 more source

Dictyostelium discoideum- assisted pharmacognosy of plant resources for discovering antivirulence molecules targeting Klebsiella pneumoniae [PDF]

open access: gold, 2023
Marcos Hernández   +6 more
openalex   +1 more source

Modelling of Neuronal Ceroid Lipofuscinosis Type 2 in Dictyostelium discoideum Suggests That Cytopathological Outcomes Result from Altered TOR Signalling

open access: yesCells, 2019
The neuronal ceroid lipofuscinoses comprise a group of neurodegenerative disorders with similar clinical manifestations whose precise mechanisms of disease are presently unknown.
Paige K. Smith   +3 more
doaj   +1 more source

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