Results 81 to 90 of about 42,471 (213)

Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum [PDF]

Genome Biology, 2011
Abstract Background The social amoebae (Dictyostelia) are a diverse group of Amoebozoa that achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with terminally differentiated spores and stalk cells.
Sucgang, Richard, Kuo, Alan, Tian, Xiangjun, Salerno, William, Parikh, Anup, Feasley, Christa L, Dalin, Eileen, Tu, Hank, Huang, Eryong, Barry, Kerrie, Lindquist, Erika, Shapiro, Harris, Bruce, David, Schmutz, Jeremy, Salamov, Asaf, Fey, Petra, Gaudet, Pascale, Anjard, Christophe, Madan Babu, M, Basu, Siddhartha, Bushmanova, Yulia, van der Wel, Hanke, Katoh-Kurasawa, Mariko, Dinh, Christopher, Coutinho, Pedro M, Saito, Tamao, Elias, Marek, Schaap, Pauline, Kay, Robert R, Henrissat, Bernard, Eichinger, Ludwig, Rivero, Francisco, Putnam, Nicholas H, West, Christopher M, Loomis, William F, Chisholm, Rex L, Shaulsky, Gad, Strassmann, Joan E, Queller, David C, Kuspa, Adam, Grigoriev, Igor V   +40 more
openaire   +3 more sources

Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds

Disease Models & Mechanisms, 2012
SUMMARY Lipid droplet formation and subsequent steatosis (the abnormal retention of lipids within a cell) has been reported to contribute to hepatotoxicity and is an adverse effect of many pharmacological agents including the antiepileptic drug valproic ...
Lucy M. Elphick, Nadine Pawolleck, Irina A. Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L. Harwood, Nick J. Plant, Robin S. B. Williams   +8 more
doaj   +1 more source

Dictyostelium cells migrate similarly on surfaces of varying chemical composition. [PDF]

PLoS ONE, 2014
During cell migration, cell-substrate binding is required for pseudopod anchoring to move the cell forward, yet the interactions with the substrate must be sufficiently weak to allow parts of the cell to de-adhere in a controlled manner during typical ...
Colin P McCann, Erin C Rericha, Chenlu Wang, Wolfgang Losert, Carole A Parent   +4 more
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, Volume 16, Issue 2, Page 268-278, February 2026.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Extracellular signaling in Dictyostelium

The International Journal of Developmental Biology, 2019
In the last few decades, we have learned a considerable amount about how eukaryotic cells communicate with each other, and what it is the cells are telling each other. The simplicity of Dictyostelium discoideum, and the wide variety of available tools to study this organism, makes it the equivalent of a hydrogen atom for cell and developmental biology.
Kristen M, Consalvo, Ramesh, Rijal, Yu, Tang, Sara A, Kirolos, Morgan R, Smith, Richard H, Gomer   +5 more
openaire   +3 more sources

The complete mitochondrial genome of Dictyostelium intermedium

Mitochondrial DNA. Part B. Resources, 2021
Dictyostelium intermedium is a member of dictyostelids, the unicellular eukaryotes with a unique life cycle, including a social cycle. Despite the high diversity of dictyostelids, only five species' complete mitochondrial genome sequences were reported ...
Kamonchat Prommarit, Passorn Wonnapinij
doaj   +1 more source

RNA interference in J774 macrophages reveals a role for coronin 1 in mycobacterial trafficking but not in actin-dependent processes [PDF]

, 2008
Macrophages are crucial for innate immunity, apoptosis, and tissue remodeling, processes that rely on the capacity of macrophages to internalize and process cargo through phagocytosis.
Rajesh Jayachandran, John Gatfield, Jan Massner, Imke Albrecht, Bettina Zanolari, Jean Pieters, Sandra Schmid, Aderem A., Allen L. A., Araki N., Brummelkamp T. R., David V., de Hostos E. L., de Hostos E. L., de Hostos E. L., Ferrari G., Ferrari G., Foger N., Gatfield J., Gerisch G., Goode B. L., Grogan A., Guerin I., Heil-Chapdelaine R. A., Humphries C. L., Itoh S., Jayachandran R., Johannes L., Maniak M., Nal B., Nguyen L., Okumura M., Pantaloni D., Parente J. A., Pieters J., Rybakin V., Scherr N., Schuller S., Smith T. F., Steinman R. M., Suzuki K., Tailleux L., Tulp A., Vieira O. V., Walburger A., Zheng P. Y.   +45 more
core   +1 more source

Highlights of the FEBS3+ meeting Exploring molecular frontiers

FEBS Open Bio, Volume 16, Issue 2, Page 240-242, February 2026.
FEBS+ meeting Exploring molecular frontiers, held in Pula, Croatia, in autumn 2024 was jointly organized by the Croatian, Finnish, and Swedish Member Societies of the Federation of European Biochemical Societies (FEBS). The congress covered a wide variety of different biochemical themes, some of the highlights of which are presented in this ‘In the ...
Morana Dulić, Hannu Koistinen, Ronnie Berntsson   +2 more
wiley   +1 more source

Dictyostelid Cellular Slime Molds from Christmas Island, Indian Ocean

mSphere, 2019
Christmas Island (10°30′S, 105°40′E) is an Australian external territory located in the Indian Ocean, approximately 350 km south of Java and Sumatra and about 1,550 km northwest of the closest point on the Australian mainland.
Pu Liu, Yue Zou, Wenxiu Li, Yu Li, Xinru Li, Songhao Che, Steven L. Stephenson   +6 more
doaj   +1 more source

The Evolutionary Reorganization of Ontogeny and Origin of Multicellularity [PDF]

, 2010
The formation of morphogenetic mechanisms during emergence of multicellularity is discussed in this ...
Dovgal, I. V.
core   +1 more source