Results 61 to 70 of about 17,348 (180)
An Unfolding Story: AlphaFold's View on Protein Flexibility
AlphaFold confidence measures allow for detailed proteome‐wide characterization of protein flexibility. All flexibility measures increased substantially in the evolutionary transition from prokaryota to eukaryota. ABSTRACT The AlphaFold confidence measures are related to conformation distribution of the protein.
Gunnar Jeschke
wiley +1 more source
Abstract Intrinsically disordered regions (IDRs) play important molecular roles in cells even though they do not adopt a stable structure. Relative to structured regions, IDRs have skewed amino acid compositions favoring polar and charged amino acids. This feature is a major contributor to the biophysical behavior and in vivo activity of IDRs, but the ...
Sean M. Cascarina +3 more
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Dictyostelid Cellular Slime Molds from Christmas Island, Indian Ocean
Christmas Island (10°30′S, 105°40′E) is an Australian external territory located in the Indian Ocean, approximately 350 km south of Java and Sumatra and about 1,550 km northwest of the closest point on the Australian mainland.
Pu Liu +6 more
doaj +1 more source
The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima +12 more
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ABSTRACT Soil recovery after contamination relies on the surviving microbiota to reconstruct microbial food webs. The ciliate Colpoda aspera and Brevundimonas sp., Rhizobium sp1, Rhizobium sp2 (gram‐negative), Bacillus sp1, Bacillus sp2, and Microbacterium sp.(gram‐positive) remain active after pulses of light petroleum contamination.
Laura Mondragón‐Camarillo +2 more
wiley +1 more source
Identification and phylogenetic analysis of
Background Kinesins constitute a large superfamily of motor proteins in eukaryotic cells. They perform diverse tasks such as vesicle and organelle transport and chromosomal segregation in a microtubule- and ATP-dependent manner.
Glöckner Gernot, Kollmar Martin
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Organisms like Dictyostelium discoideum, often referred to as DNA damage "extremophiles", can survive exposure to extremely high doses of radiation and DNA crosslinking agents. These agents form highly toxic DNA crosslinks that cause extensive DNA damage.
Xiao-Yin Zhang +5 more
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Background Development of the post-genomic age in Dictyostelium will require the existence of rapid and reliable methods to disrupt genes that would allow the analysis of entire gene families and perhaps the possibility to undertake the complete knock ...
Escalante Ricardo +2 more
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Resistance to phagocyte killing is an important virulence factor in mycobacteria. Dictyostelium has been used to study the interaction between phagocytes and bacteria, given its similarity to the mammalian macrophage.
Yi-Yin eChen +5 more
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