Results 61 to 70 of about 28,273 (219)
Frontiers in Neuroscience, 2022 Microsatellites are repetitive sequences commonly found in the genomes of higher organisms. These repetitive sequences are prone to expansion or contraction, and when microsatellite expansion occurs in the regulatory or coding regions of genes this can ...
Felicia N. Williams +3 more
doaj +1 more source
Characterisation of Aardvark, a Dictyostelium ß-catenin. [PDF]
, 2003 Wnt signalling is active both in development and the progression of certain disease processes, most notably cancer. Glycogen Synthase Kinase-3 (GSK-3) and ß-catenin both define the canonical Wnt pathway, where GSK-3 negatively regulates ß-catenin ...
Reynolds, Jonathan Peter, Reynolds, JP
core
Digital image processing of optical density wave propagation in Dictyostelium discoideum and analysis of the effects of caffeine and ammonia [PDF]
, 1989 Waves of chemotactic movement during the early phase of aggregation in Dictyostelium discoideum were analyzed by digital image processing in a manner that immediately shows the following parameters: wave propagation velocity, period length, wave ...
Siegert, Florian, Weijer, Cornelis J.
core +1 more source
Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.Free‐living amoebae may provide an underrecognised environmental niche for Helicobacter pylori, supporting its intracellular persistence, morphological plasticity, and protection from environmental stress. These interactions could facilitate prolonged survival in aquatic and food‐associated environments and contribute to potential waterborne or ...
Otmane Lamrabet +7 more
wiley +1 more source
FEBS Letters, Volume 600, Issue 17, Page 2564-2578, September 2026.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The role of the cortical cytoskeleton [PDF]
, 1996 We generated Dictyostelium double mutants lacking the two F-actin crosslinking proteins alpha-actinin and gelation factor by inactivating the corresponding genes via homologous recombination.
Schleicher, Michael +8 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2013 Dictyostelium cells are forest soil amoebae, which feed on bacteria and proliferate as solitary cells until bacteria are consumed. Starvation triggers a change in life style, forcing cells to gather into aggregates to form multicellular organisms ...
Salvatore eBozzaro +2 more
doaj +1 more source
CRISPR Toolbox for Genome Editing in Dictyostelium
Frontiers in Cell and Developmental Biology, 2021 The development of new techniques to create gene knockouts and knock-ins is essential for successful investigation of gene functions and elucidation of the causes of diseases and their associated fundamental cellular processes.
Kensuke Yamashita +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, Volume 600, Issue 17, Page 2420-2436, September 2026.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Extracellular signaling in Dictyostelium
The International Journal of Developmental Biology, 2019 In the last few decades, we have learned a considerable amount about how eukaryotic cells communicate with each other, and what it is the cells are telling each other. The simplicity of Dictyostelium discoideum, and the wide variety of available tools to study this organism, makes it the equivalent of a hydrogen atom for cell and developmental biology.
Kristen M, Consalvo +5 more
openaire +3 more sources