Results 41 to 50 of about 17,348 (180)

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, EarlyView.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

Reproducibility assessment of a published cell shape transition analysis workflow

Journal of Microscopy, EarlyView.
Abstract Image quantification is central to modern biomedical research. However, the reproducibility of image‐based studies remains a persistent challenge due to limited access to raw data and incomplete reporting of analysis workflows. To assess these issues, the Global Bioimage Analyst Society (GloBIAS) launched a coordinated effort in 2024 to ...
Esteban A. Miglietta, An‐Chi Luo, Agustin A. Corbat, Shao‐Chun Hsu   +3 more
wiley   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf, Paul Nouri, Frédéric Galisson, Laetitia Daury, Marie‐France Giraud, Olivier Lambert, Cédric Orelle, Lionel Ballut, Elise Kaplan, Jean‐Michel Jault, Cécile Gonzalez   +10 more
wiley   +1 more source

The 3D genome of Gigaspora margarita unveils stable chromatin and nucleolar organization and symbiont‐dependent genome dynamics

New Phytologist, Volume 251, Issue 5, Page 2799-2817, September 2026.
Summary Arbuscular mycorrhizal fungi (AMF) are widespread plant symbionts that enhance nutrient acquisition and influence ecosystem productivity. Previous chromosome‐level assemblies of the model species Rhizophagus irregularis revealed a two‐compartment genome architecture (active A and repressed B chromatin compartments), yet its conservation across ...
Ken Mugambi, Jordana Oliveira, Franco Magurno, Alessandra Salvioli di Fossalunga, Mara Novero, Luisa Lanfranco, Stefano Ghignone, Gökalp Yildirir, Yan Wang, Paola Bonfante, Nicolas Corradi   +10 more
wiley   +1 more source

CRISPR Toolbox for Genome Editing in Dictyostelium

Frontiers in Cell and Developmental Biology, 2021
The development of new techniques to create gene knockouts and knock-ins is essential for successful investigation of gene functions and elucidation of the causes of diseases and their associated fundamental cellular processes.
Kensuke Yamashita, Hoshie Iriki, Yoichiro Kamimura, Tetsuya Muramoto   +3 more
doaj   +1 more source

Recent Advances in CRISPR/Cas9-Mediated Genome Editing in Dictyostelium

Cells, 2019
In the last 30 years, knockout of target genes via homologous recombination has been widely performed to clarify the physiological functions of proteins in Dictyostelium.
Tetsuya Muramoto, Hoshie Iriki, Jun Watanabe, Takefumi Kawata   +3 more
doaj   +1 more source

A recombinant antibody toolbox for Dictyostelium discoideum

BMC Research Notes, 2020
Objective The amoeba Dictyostelium discoideum has been a valuable model organism to study numerous facets of eukaryotic cell biology, such as cell motility, cell adhesion, macropinocytosis and phagocytosis, host–pathogen interactions and multicellular ...
Wanessa C. Lima, Philippe Hammel, Pierre Cosson   +2 more
doaj   +1 more source

Multilevel genomic constraints shape nuclear tRNA gene organization in plants

The Plant Journal, Volume 127, Issue 3, August 2026.
SUMMARY Transfer RNAs (tRNAs) are essential components of the translation machinery. Their abundance and diversity shape decoding capacity as well as the efficiency and accuracy of protein synthesis. Because tRNA abundance is encoded in the genome through tDNA copy number, chromosomal organization, and cis‐regulatory sequences controlling transcription,
Guillaume Hummel, David Pflieger, Valérie Cognat, Laurence Drouard, Alexandre Berr   +4 more
wiley   +1 more source

An anatomy ontology to represent biological knowledge in Dictyostelium discoideum

BMC Genomics, 2008
Background Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction.
Fey Petra, Williams Jeffery G, Gaudet Pascale, Chisholm Rex L   +3 more
doaj   +1 more source

A Novel Polyphosphate‐Degrading Enzyme Confers Growth on Exogenous Polyphosphate in the Archaeon Haloferax volcanii

Environmental Microbiology, Volume 28, Issue 7, July 2026.
A novel polyP‐degrading enzyme with an activity differing from those currently known was found in Haloferax volcanii, conferring the ability for this microbe to grow on extracellular polyP. These findings further our understanding of the potential ecological roles of polyP and how archaea metabolise this essential biopolymer.
Jack W. F. Nicholls, Vincent O'Flaherty, Timothy M. Lenton, John W. McGrath, Jason P. Chin   +4 more
wiley   +1 more source