Results 31 to 40 of about 28,273 (219)

Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein [PDF]

open access: yes, 2009
Background: SCAR/WAVE proteins couple signalling to actin polymerization, and are thus fundamental to the formation of pseudopods and lamellipods. They are controlled as part of a five-membered complex that includes the tiny HSPC300 protein.
Alice Y Pollitt   +9 more
core   +1 more source

Dictyostelium discoideum as a Model for Investigating Neurodegenerative Diseases

open access: yesFrontiers in Cellular Neuroscience, 2021
The social amoeba Dictyostelium discoideum is a model organism that is used to investigate many cellular processes including chemotaxis, cell motility, cell differentiation, and human disease pathogenesis.
Holly N. Haver   +3 more
doaj   +1 more source

OXYGEN GRADIENTS CAUSE PATTERN ORIENTATION IN DICTYOSTELIUM CELL CLUMPS [PDF]

open access: yes, 1981
We have investigated the formation of the prestalk-prespore pattern in Dictyottelium discoideum. Pattern formation occurs in clumps of Dictyostelium cells embedded in agar under a 100% oxygen atmosphere.
Sternfeld, John, David, Charles N.
core   +1 more source

Investigation of a potential role for aldose reductase AlrA in tetrahydropteridine synthesis in Dictyostelium discoideum Ax2

open access: yesPteridines, 2017
Dictyostelium discoideum Ax2 is well-known for the synthesis of d-threo-tetrahydrobiopterin (DH4) with a smaller amount of l-erythro-tetrahydrobiopterin (BH4).
Kim Hye-Lim   +2 more
doaj   +1 more source

Development of a Positive Selection High Throughput Genetic Screen in Dictyostelium discoideum

open access: yesFrontiers in Cell and Developmental Biology, 2021
The cellular slime mold Dictyostelium discoideum is a powerful model organism that can be utilized to investigate human health and disease. One particular strength of Dictyostelium is that it can be utilized for high throughput genetic screens.
Felicia N. Williams   +4 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer. [PDF]

open access: yesFEBS Open Bio
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Lamrabet O, Cosson P.
europepmc   +2 more sources

Fate and regulation of anterior-like cells in Dictyostelium slugs [PDF]

open access: yes, 1982
A pattern of two tissue types exists in the Dictyostelium slug. Contained within the posterior tissue are anterior-like cells which comprise about 10% of the developing cell mass.
Sternfeld, John   +3 more
core   +1 more source

BTG interacts with retinoblastoma to control cell fate in Dictyostelium. [PDF]

open access: yes, 2010
In the genesis of many tissues, a phase of cell proliferation is followed by cell cycle exit and terminal differentiation. The latter two processes overlap: genes involved in the cessation of growth may also be important in triggering differentiation ...
Adriano Ceccarelli   +9 more
core   +2 more sources

Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells [PDF]

open access: yes, 1994
There are cells acattered in the rear, prespore region of the Dictyostelium slug that share many of the properties of the prestalk cells and that are therefore called anterior-like cells (ALCs).
Early, Anne   +4 more
core   +1 more source

Protection of spores from ultraviolet-C irradiation by auto-fluorescent substances in the spore mass of the cellular slime mold Dictyostelium discoideum

open access: yesPteridines, 2014
In this study, native spores surrounded by fluorescent substances in the spore mass of Dictyostelium discoideum were found to be resistant to relatively strong ultraviolet-C (UV-C) irradiation (2880 J/m2).
Uchiyama Saburo, Hatakeyama Ikuo
doaj   +1 more source

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