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Cells, 2021 The social amoeba Dictyostelium discoideum provides an excellent model for research across a broad range of disciplines within biology. The organism diverged from the plant, yeast, fungi and animal kingdoms around 1 billion years ago but retains common ...
Robin S. B. Williams +6 more
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Bacterial Survival in Dictyostelium [PDF]
BIO-PROTOCOL, 2017 We performed an assay to test the ability of different E. coli strains to survive inside amoebal cells after ingestion. In the assay we incubated bacteria together with cells of Dictyostelium discoideum for six hours. After co-incubation most of the uningested bacteria were removed by centrifugation and the remaining uningested bacteria were killed by ...
Regin Rønn +10 more
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MAPKs in development: insights from Dictyostelium signaling pathways
Biomolecular Concepts, 2011 Mitogen activated protein kinases (MAPKs) play important roles in the development of eukaryotic organisms through the regulation of signal transduction pathways stimulated by external signals.
Hadwiger Jeffrey A., Nguyen Hoai-Nghia
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Cell Sorting daring Pattern Formation in Dictyostelium [PDF]
, 1981 Formation of the prestalk-prespore pattern in Dictyostelium was investigated in slugs and submerged clumps of cells. Prestalk and prespore cells were identified by staining with vital dyes, which are shown to be stable cell markers.
Sternfeld, John, David, Charles N.
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Lysosomes appear as the auto-fluorescent vacuoles in Dictyostelium discoideum cells
Pteridines, 2016 Dictyostelium discoideum cells contain auto-fluorescent vacuoles. To determine the identity of these vacuoles, the fluorescent dye 4-nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole (NBD-PZ) was used to stain the lysosomes in D. discoideum cells. Neither the
Kainuma Hiroki +4 more
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ABC transporters in Dictyostelium discoideum development [PDF]
, 2013 ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins.
Adam Kuspa +27 more
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A gradient method for the quantitative analysis of cell movement and tissue flow and its application to the analysis of multicellular Dictyostelium development [PDF]
, 1994 We describe the application of a novel image processing method, which allows quantitative analysis of cell and tissue movement in a series of digitized video images. The result is a vector velocity field showing average direction and velocity of movement
Nomura, Atsushi +3 more
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Stochastic noise and synchronisation during Dictyostelium aggregation make cAMP oscillations robust [PDF]
, 2007 Stable and robust oscillations in the concentration of adenosine 3′, 5′-cyclic monophosphate (cAMP) are observed during the aggregation phase of starvation-induced development in Dictyostelium discoideum.
Postlethwaite Ian +23 more
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Frontiers in Cellular and Infection Microbiology, 2017 Infections with filamentous fungi are common to all animals, but attention is rising especially due to the increasing incidence and high mortality rates observed in immunocompromised human individuals. Here, Aspergillus fumigatus and other members of its
Silvia Novohradská +4 more
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Dictyostelium discoideum as a non‐mammalian biomedical model
Microbial Biotechnology, 2021 Summary Dictyostelium discoideum is one of eight non‐mammalian model organisms recognized by the National Institute of Health for the study of human pathology. The use of this slime mould is possible owing to similarities in cell structure, behaviour and
Javier Martín‐González +2 more
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