Results 11 to 20 of about 42,471 (213)

The Dictyostelium Centrosome [PDF]

open access: yesCells, 2021
The centrosome of Dictyostelium amoebae contains no centrioles and consists of a cylindrical layered core structure surrounded by a corona harboring microtubule-nucleating γ-tubulin complexes. It is the major centrosomal model beyond animals and yeasts.
Ralph Gräf   +4 more
openaire   +3 more sources

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium. [PDF]

open access: yesFEBS Open Bio
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Yamashita TR, Usuki T, Kay RR, Saito T.
europepmc   +2 more sources

The proppin Bcas3 and its interactor KinkyA localize to the early phagophore and regulate autophagy [PDF]

open access: yes, 2021
To resolve the signaling mechanisms that mediate the starvation-induced processes of Dictyostelium sporulation and encystation, we performed insertional mutagenesis on cells harboring an mRFP-tagged spore gene.
Schaap, Pauline, Yamada, Yoko
core   +2 more sources

Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase [PDF]

open access: yesOpen Biology, 2015
The network of protein–protein interactions of the Dictyostelium discoideum autophagy pathway was investigated by yeast two-hybrid screening of the conserved autophagic proteins Atg1 and Atg8.
Ana Mesquita   +5 more
doaj   +1 more source

Gel purification of gDNA for next-generation sequencing applications

open access: yesBioTechniques, 2022
We demonstrate that gDNA can be conveniently and efficiently isolated and purified using standard agarose gel electrophoresis, band excision and gel purification.
Supanut Utthiya   +6 more
doaj   +1 more source

Cooperative cell motility during tandem locomotion of amoeboid cells. [PDF]

open access: yes, 2016
Streams of migratory cells are initiated by the formation of tandem pairs of cells connected head to tail to which other cells subsequently adhere. The mechanisms regulating the transition from single to streaming cell migration remain elusive, although ...
Bastounis, Effie   +4 more
core   +2 more sources

Visualization of c-di-GMP in multicellular Dictyostelium stages

open access: yesFrontiers in Cell and Developmental Biology, 2023
The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes.
Hayato Ide   +3 more
doaj   +1 more source

Dyskerin Mutations Present in Dyskeratosis Congenita Patients Increase Oxidative Stress and DNA Damage Signalling in Dictyostelium Discoideum

open access: yesCells, 2019
Dyskerin is a protein involved in the formation of small nucleolar and small Cajal body ribonucleoproteins. These complexes participate in RNA pseudouridylation and are also components of the telomerase complex required for telomere elongation.
Javier Rodriguez-Centeno   +2 more
doaj   +1 more source

Moving the Research Forward: The Best of British Biology Using the Tractable Model System Dictyostelium discoideum

open access: yesCells, 2021
The social amoeba Dictyostelium discoideum provides an excellent model for research across a broad range of disciplines within biology. The organism diverged from the plant, yeast, fungi and animal kingdoms around 1 billion years ago but retains common ...
Robin S. B. Williams   +6 more
doaj   +1 more source

MAPKs in development: insights from Dictyostelium signaling pathways

open access: yesBiomolecular Concepts, 2011
Mitogen activated protein kinases (MAPKs) play important roles in the development of eukaryotic organisms through the regulation of signal transduction pathways stimulated by external signals.
Hadwiger Jeffrey A., Nguyen Hoai-Nghia
doaj   +1 more source

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