Results 81 to 90 of about 52,165 (246)

Dictyostelium: The Mathematician's Organism [PDF]

open access: yesCurrent Genomics, 2013
This article was to have been written by Kees Weijer, an outstanding pioneer in Dictyostelium research. It was (and is) to celebrate J.T. Bonner's and Weijer's contributions to the field and those of the other great pioneers. Unfortunately, Weijer was unable to write his article, due to ill health and since I have some knowledge of this field, I took ...
openaire   +3 more sources

The Evolutionary Reorganization of Ontogeny and Origin of Multicellularity [PDF]

open access: yes, 2010
The formation of morphogenetic mechanisms during emergence of multicellularity is discussed in this ...
Dovgal, I. V.
core   +1 more source

Loss of Cln3 function in the social amoeba Dictyostelium discoideum causes pleiotropic effects that are rescued by human CLN3.

open access: yesPLoS ONE, 2014
The neuronal ceroid lipofuscinoses (NCL) are a group of inherited, severe neurodegenerative disorders also known as Batten disease. Juvenile NCL (JNCL) is caused by recessive loss-of-function mutations in CLN3, which encodes a transmembrane protein that ...
Robert J Huber   +2 more
doaj   +1 more source

Cytokinin Detection during the Dictyostelium discoideum Life Cycle: Profiles Are Dynamic and Affect Cell Growth and Spore Germination

open access: yesBiomolecules, 2019
Cytokinins (CKs) are a family of evolutionarily conserved growth regulating hormones. While CKs are well-characterized in plant systems, these N6-substituted adenine derivatives are found in a variety of organisms beyond plants, including bacteria, fungi,
Megan M. Aoki   +6 more
doaj   +1 more source

Cell migration directionality and speed are independently regulated by RasG and Gβ in Dictyostelium cells in electrotaxis. [PDF]

open access: yes, 2019
Motile cells manifest increased migration speed and directionality in gradients of stimuli, including chemoattractants, electrical potential and substratum stiffness.
Devreotes, Peter N   +6 more
core  

Modeling multi-cellular systems using sub-cellular elements [PDF]

open access: yes, 2005
We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamental dynamical variables in the model are sub-cellular elements, which interact with each other through phenomenological intra- and inter-cellular ...
Newman, T. J.
core   +2 more sources

A Comprehensive Review on Capillary Electrophoresis–Mass Spectrometry in Advancing Biomolecular Research

open access: yesELECTROPHORESIS, Volume 46, Issue 15, Page 1053-1073, August 15, 2025.
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont   +2 more
wiley   +1 more source

Hisactophilin is involved in osmoprotection in Dictyostelium [PDF]

open access: yesBMC Biochemistry, 2002
Dictyostelium cells exhibit an unusual stress response as they protect themselves against hyperosmotic stress. Cytoskeletal proteins are recruited from the cytosolic pool to the cell cortex, thereby reinforcing it. In order to gain more insight into the osmoprotective mechanisms of this amoeba, we used 1-D and 2-D gel electrophoresis to identify new ...
Tanja Pintsch   +3 more
openaire   +3 more sources

Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds

open access: yesDisease Models & Mechanisms, 2012
SUMMARY Lipid droplet formation and subsequent steatosis (the abnormal retention of lipids within a cell) has been reported to contribute to hepatotoxicity and is an adverse effect of many pharmacological agents including the antiepileptic drug valproic ...
Lucy M. Elphick   +8 more
doaj   +1 more source

Dictyostelium cells migrate similarly on surfaces of varying chemical composition. [PDF]

open access: yesPLoS ONE, 2014
During cell migration, cell-substrate binding is required for pseudopod anchoring to move the cell forward, yet the interactions with the substrate must be sufficiently weak to allow parts of the cell to de-adhere in a controlled manner during typical ...
Colin P McCann   +4 more
doaj   +1 more source

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