Results 81 to 90 of about 38,088 (249)

Functional and Morphological Plasticity of the Endolysosomal System: Pigment Organelles at the Crossroads of Physiology and Pathology

Biology of the Cell, Volume 117, Issue 10, October 2025.
The morphodynamical plasticity of the endolysosomal system supports the formation and function of specialized intracellular compartments, as exemplified by the pigment organelles in skin cells. In epidermal melanocytes and keratinocytes, membrane trafficking and remodeling coordinate tissue pigmentation and protect the genome from photodamage ...
Laura Salavessa, Myckaëla Rouabah, Paula Pernea, Smail Hadj‐Rabia, Cédric Delevoye   +4 more
wiley   +1 more source

Neue Werkzeuge für die Inositolpyrophosphat‐Forschung: Stereoselektive Synthese und Einsatz von PP‐InsP₄‐Isomeren in der Pflanzenforschung

Angewandte Chemie, Volume 137, Issue 36, September 1, 2025.
Stereochemically defined inositol pyrophosphate isomers (PP‐InsP4) were synthesized and assigned by NMR spectroscopy using a chiral solvating reagent. In the form of isotopically labeled standards, they were applied in CE‐MS‐based profiling of plant extracts and kinase assays, enabling structural reassignment and functional insight into enzymatic ...
Kevin Ritter, Anne‐Sophie C. Braun, Guizhen Liu, Mengsi Lu, Verena Gaugler, Gabriel Schaaf, Henning Jacob Jessen   +6 more
wiley   +1 more source

Dictyostelid Cellular Slime Molds from Christmas Island, Indian Ocean

mSphere, 2019
Christmas Island (10°30′S, 105°40′E) is an Australian external territory located in the Indian Ocean, approximately 350 km south of Java and Sumatra and about 1,550 km northwest of the closest point on the Australian mainland.
Pu Liu, Yue Zou, Wenxiu Li, Yu Li, Xinru Li, Songhao Che, Steven L. Stephenson   +6 more
doaj   +1 more source

Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP‐InsP4 Isomers in Plant Signaling

Angewandte Chemie International Edition, Volume 64, Issue 36, September 1, 2025.
Stereochemically defined inositol pyrophosphate isomers (PP‐InsP4) were synthesized and assigned by NMR spectroscopy using a chiral solvating agent. In the form of isotopically labeled standards, they were applied in CE‐MS‐based profiling of plant extracts and kinase assays, enabling structural reassignment and functional insight into enzymatic ...
Kevin Ritter, Anne‐Sophie C. Braun, Guizhen Liu, Mengsi Lu, Verena Gaugler, Gabriel Schaaf, Henning Jacob Jessen   +6 more
wiley   +1 more source

Intracellular killing of bacteria: is Dictyostelium a model macrophage or an alien?

Cellular Microbiology, 2014
Predation of bacteria by phagocytic cells was first developed during evolution by environmental amoebae. Many of the core mechanisms used by amoebae to sense, ingest and kill bacteria have also been conserved in specialized phagocytic cells in mammalian ...
P. Cosson, Wanessa C. Lima
semanticscholar   +1 more source

Self‐supervised denoising for medical imaging enhancement

BMEMat, Volume 3, Issue 3, September 2025.
Optical microscopy is a fundamental tool of clinical imaging. AI‐driven self‐supervised denoising techniques enhance optical microscopy imaging, enabling high‐resolution long‐term tracking of in vivo and in vitro cells with minimal photodamage. This breakthrough improves clinical tools for molecular tracking, protein interaction studies, and drug ...
Guoxun Zhang, Yuanyuan Wei, Ho‐Pui Ho
wiley   +1 more source

β‐Catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function

Developmental Dynamics, Volume 254, Issue 9, Page 1055-1067, September 2025.
Abstract Background The emergence of multicellularity in animals marks a pivotal evolutionary event, which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β‐Catenin is significant to this transition due to its dual role as both a structural component in the cadherin–catenin complex and as a ...
Brian M. Walters, Lucas J. Guttieres, Mayline Goëb, Stanley J. Marjenberg, Mark Q. Martindale, Athula H. Wikramanayake   +5 more
wiley   +1 more source

The annexins of Dictyostelium

European Journal of Cell Biology, 2006
Annexins are a highly conserved ubiquitous family of Ca2+- and phospholipid-binding proteins present in nearly all eukaryotic cells. Analysis of the Dictyostelium genome revealed the presence of two annexin genes, the annexin C1 gene (nxnA) giving rise to two isoforms of 47 and 51 kDa (previously synexin), and the annexin C2 gene (nxnB) coding for a 56-
Marija, Marko, Yogikala, Prabhu, Rolf, Müller, Rosemarie, Blau-Wasser, Michael, Schleicher, Angelika A, Noegel   +5 more
openaire   +2 more sources

Mycobacterium marinum mmar_2318 and mmar_2319 are Responsible for Lipooligosaccharide Biosynthesis and Virulence towards Dictyostelium

Frontiers in Microbiology, 2016
Resistance to phagocyte killing is an important virulence factor in mycobacteria. Dictyostelium has been used to study the interaction between phagocytes and bacteria, given its similarity to the mammalian macrophage.
Yi-Yin eChen, Feng-Ling eYang, Shih-Hsiung eWu, Tzu-Lung eLin, Jin-Town eWang, Jin-Town eWang   +5 more
doaj   +1 more source

Dictyostelium development: Lower STATs [PDF]

Current Biology, 1997
The discovery of a STAT protein in Dictyostelium indicates that this organism uses phosphotyrosine-SH2-domain signalling during development. Such signalling is lacking in yeast and its appearance may therefore be an early step in the evolution of multicellularity.
openaire   +2 more sources