SILAC-based proteomic quantification of chemoattractant-induced cytoskeleton dynamics on a second to minute timescale [PDF]
Cytoskeletal dynamics during cell behaviours ranging from endocytosis and exocytosis to cell division and movement is controlled by a complex network of signalling pathways, the full details of which are as yet unresolved.
A Bagorda +60 more
core +3 more sources
Retrotransposon Domestication and Control in Dictyostelium discoideum
Transposable elements, identified in all eukaryotes, are mobile genetic units that can change their genomic position. Transposons usually employ an excision and reintegration mechanism, by which they change position, but not copy number.
Marek Malicki +2 more
doaj +1 more source
Development of a Positive Selection High Throughput Genetic Screen in Dictyostelium discoideum
The cellular slime mold Dictyostelium discoideum is a powerful model organism that can be utilized to investigate human health and disease. One particular strength of Dictyostelium is that it can be utilized for high throughput genetic screens.
Felicia N. Williams +4 more
doaj +1 more source
Profilin isoforms in Dictyostelium discoideum
Eukaryotic cells contain a large number of actin binding proteins of different functions, locations and concentrations. They bind either to monomeric actin (G-actin) or to actin filaments (F-actin) and thus regulate the dynamic rearrangement of the actin cytoskeleton.
Arasada, Rajesh +8 more
openaire +2 more sources
Models of Dictyostelium discoideum Aggregation [PDF]
Since its discovery in the 1940’s, the life cycle of the cellular slime mould Dictyostelium discoideum has attracted the interest of developmental biologists. It involves a relatively simple transition from unicellular to multicellular organization. Briefly, amoebae feed on bacteria in the soil and divide.
Dallon, J +6 more
openaire +3 more sources
Alkaline Phosphatase in Dictyostelium discoideum [PDF]
Several phosphatases have been demonstrated in Dictyostelium discoideum. The alkaline phosphatase, pH optimum 9·0, is a 5′-nucleotidase, attacking adenosine monophosphate and deoxyadenosine monophosphate, but catalyses also hydrolysis of p-nitrophenyl phosphate.
K, GEZELIUS, B E, WRIGHT
openaire +2 more sources
Origin and evolution of the slime molds (Mycetozoa) [PDF]
The Mycetozoa include the cellular (dictyostelid), acellular (myxogastrid), and protostelid slime molds. However, available molecular data are in disagreement on both the monophyly and phylogenetic position of the group.
Baldauf, S.L., Doolittle, W.F.
core +2 more sources
Dictyostelium discoideum as a Model for Investigating Neurodegenerative Diseases
The social amoeba Dictyostelium discoideum is a model organism that is used to investigate many cellular processes including chemotaxis, cell motility, cell differentiation, and human disease pathogenesis.
Holly N. Haver +3 more
doaj +1 more source
Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum
Development of the soil amoeba Dictyostelium discoideum is triggered by starvation. When placed on a solid substrate, the starving solitary amoebae cease growth, communicate via extracellular cAMP, aggregate by tens of thousands and develop into ...
Rafael D. Rosengarten +6 more
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

