Results 41 to 50 of about 41,925 (254)

The dictyostelium kinome--analysis of the protein kinases from a simple model organism. [PDF]

PLoS Genetics, 2006
Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases, similar to the count of the much more advanced ...
Jonathan M Goldberg, Gerard Manning, Allen Liu, Petra Fey, Karen E Pilcher, Yanji Xu, Janet L Smith   +6 more
doaj   +2 more sources

Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum.

PLoS Genetics, 2009
Organisms like Dictyostelium discoideum, often referred to as DNA damage "extremophiles", can survive exposure to extremely high doses of radiation and DNA crosslinking agents. These agents form highly toxic DNA crosslinks that cause extensive DNA damage.
Xiao-Yin Zhang, Judith Langenick, David Traynor, M Madan Babu, Rob R Kay, Ketan J Patel   +5 more
doaj   +1 more source

Cooperative cell motility during tandem locomotion of amoeboid cells. [PDF]

, 2016
Streams of migratory cells are initiated by the formation of tandem pairs of cells connected head to tail to which other cells subsequently adhere. The mechanisms regulating the transition from single to streaming cell migration remain elusive, although ...
Bastounis, Effie, del Álamo, Juan C, Firtel, Richard A, Lasheras, Juan C, Álvarez-González, Begoña   +4 more
core   +2 more sources

Dictyostelium discoideum transformation by oscillating electric field electroporation

BioTechniques, 2003
Dictyostelium discoideum has been used as a genetically tractable model organism to study many biological phenomena. High-efficiency transformation is a prerequisite for successful genetic screens such as mutant complementation, identification of ...
Laeticia Alibaud, Pierre Cosson, Mohammed Benghezal   +2 more
doaj   +1 more source

Inference of the drivers of collective movement in two cell types: Dictyostelium and melanoma [PDF]

, 2016
Collective cell movement is a key component of many important biological processes, including wound healing, the immune response and the spread of cancers.
Ferguson, Elaine A., Husmeier, Dirk, Insall, Robert H., Matthiopoulos, Jason   +3 more
core   +2 more sources

Leaps and lulls in the developmental transcriptome of Dictyostelium discoideum

BMC Genomics, 2015
Development of the soil amoeba Dictyostelium discoideum is triggered by starvation. When placed on a solid substrate, the starving solitary amoebae cease growth, communicate via extracellular cAMP, aggregate by tens of thousands and develop into ...
R. Rosengarten, Balaji Santhanam, D. Fuller, Mariko Katoh-Kurasawa, W. Loomis, B. Zupan, G. Shaulsky   +6 more
semanticscholar   +1 more source

Fluctuation theorem applied to Dictyostelium discoideum system [PDF]

, 2007
In this paper, we analyze the electrotactic movement of Dictyostelium discoideum from the viewpoint of non-equilibrium statistical mechanics. Because we can observe fluctuating behavior of cellular trajectories, we analyze the probability distribution of
Ciliberto S., Crisanti A., Feitosa K., Hayashi K., Miyoshi H., Sato M. J., Selmeczi D., Uchida K. S., Wang G. M., Zhao M.   +9 more
core   +1 more source

Dictyostelium discoideum as a Model for Investigating Neurodegenerative Diseases

Frontiers in Cellular Neuroscience, 2021
The social amoeba Dictyostelium discoideum is a model organism that is used to investigate many cellular processes including chemotaxis, cell motility, cell differentiation, and human disease pathogenesis.
Holly N. Haver, K. Matthew Scaglione, K. Matthew Scaglione, K. Matthew Scaglione   +3 more
doaj   +1 more source

Profilin isoforms in Dictyostelium discoideum

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2007
Eukaryotic cells contain a large number of actin binding proteins of different functions, locations and concentrations. They bind either to monomeric actin (G-actin) or to actin filaments (F-actin) and thus regulate the dynamic rearrangement of the actin cytoskeleton.
Arasada, Rajesh, Gloss, Annika, Tunggal, Budi, Joseph, Jayabalan M., Rieger, Daniela, Mondal, Subhanjan, Faix, Jan, Schleicher, Michael, Noegel, Angelika A.   +8 more
openaire   +2 more sources

Models of Dictyostelium discoideum Aggregation [PDF]

, 1997
Since its discovery in the 1940’s, the life cycle of the cellular slime mould Dictyostelium discoideum has attracted the interest of developmental biologists. It involves a relatively simple transition from unicellular to multicellular organization. Briefly, amoebae feed on bacteria in the soil and divide.
Dallon, J, Othmer, H, Van Oss, C, Panfilov, A, Hogeweg, P, Hofer, T, Maini, P   +6 more
openaire   +3 more sources