Results 11 to 20 of about 1,384 (167)

Diabetes mellitus, diabetes insipidus, optic atrophy and deafness (DIDMOAD syndrome)

The Turkish Journal of Pediatrics, 1990
Two patients with diabetes mellitus (DM), diabetes insipidus (DI), optic atrophy (OA), deafness (D) and dilatation of the urinary tract-the so-called DIDMOAD syndrome are presented. In one of the patients, the presenting components were DI and OA.
U Saatçi, O Söylemezoğlu, S Ozen, N Yordam, O Saatçi   +4 more
doaj   +5 more sources

Various clinical aspects of DIDMOAD (Wolfram) syndrome

The Turkish Journal of Pediatrics, 1995
The association of juvenile diabetes mellitus (DM), diabetes insipidus (DI), optic atrophy (OA) and sensorineural deafness (D) is known as DIDMOAD or Wolfram syndrome. Aside from these four cardinal features, a wide variety of abnormalities of the
A Okten, Y Gedik, A Demirci, H Mocan, E Erduran, Y Aslan   +5 more
doaj   +3 more sources

Optic atrophy in Wolfram (DIDMOAD) syndrome [PDF]

Eye, 1997
Wolfram syndrome is the association of diabetes mellitus and optic atrophy, also called DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy and deafness). Incomplete characterisation has caused diagnostic confusion; we therefore undertook a nation-wide cross-sectional case finding study. We identified 45 patients with Wolfram syndrome, median
T G, Barrett, S E, Bundey, A R, Fielder, P A, Good   +3 more
openaire   +3 more sources

Wolfram (DIDMOAD) Sendromu: Olgu Sunumu

Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi, 2022
Özet Wolfram sendromu, diyabetes mellitus, optik atrofi, diyabetes insipitus, işitme kaybı ile karakterize otozomal resesif geçiş gösteren genetik bir hastalıktır. Hastalarda nörolojik rahatsızlıklar, üriner sistem hastalıkları ve psikolojik rahatsızlıklarda izlenir.
Eda ALTUN, Saime PAYDAS, Bülent KAYA, İbrahim KARAYAYLALI   +3 more
openaire   +2 more sources

Identification of Three Novel and One Known Mutation in the WFS1 Gene in Four Unrelated Turkish Families: The Role of Homozygosity Mapping in the Early Diagnosis

JCRPE, 2021
Objective:Bi-allelic mutations in the wolframin gene (WFS1) cause Wolfram syndrome 1 (WS1 or DIDMOAD) characterized by non-autoimmune diabetes mellitus, optic atrophy, diabetes insipidus, sensorineural deafness, urinary tract abnormalities, and ...
Maha Sherif, Hüseyin Demirbilek, Atilla Çayır, Sophia Tahir, Büşra Çavdarlı, Meliha Demiral, Ayşe Nurcan Cebeci, Doğuş Vurallı, Sofia Asim Rahman, Edip Unal, Gönül Büyükyılmaz, Riza Taner Baran, Mehmet Nuri Özbek, Khalid Hussain   +13 more
doaj   +2 more sources

A case Report of Wolfram Syndrome

Journal of Rehabilitation, 2007
Wolfram syndrome is the association of diabetes mellitus, optic atrophy, diabetes insipidus and sensorineural deafness and is sometimes called DIDMOAD (Diabetes Insipidus, Diabets Mellitus, Optic Atrophy, and Deafness).
Zahra Razavi, Mohammad Mehdi Taghdiri
doaj   +1 more source

The tale of Wolfram syndrome in a young child versus an adolescent: Two case reports

Indian Journal of Ophthalmology. Case Reports, 2023
Wolfram Syndrome (WS) is a rare autosomal recessive progressive neurodegenerative disorder characterized by juvenile-onset diabetes mellitus (DM) and optic atrophy (OA), known as DIDMOAD (diabetes insipidus [DI], diabetes mellitus, optic atrophy ...
Hirika Gosalia, Soveeta Rath, Virna M Shah, Suma Ganesh   +3 more
doaj   +1 more source

DIDMOAD syndrome with megacystis and megaureter [PDF]

Postgraduate Medical Journal, 1986
SummaryA case of DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and nerve deafness) is described. There was unusually severe urinary tract dilatation which led to an ileal conduit diversion. Immunohistological study of the bladder wall and ureter revealed a marked diminution in nerve fibres, which may have been primary or ...
P, Chu, W G, Staff, J A, Morris, J M, Polak   +3 more
openaire   +2 more sources

Wolfram syndrome: Portuguese research

Endokrynologia Polska, 2021
INTRODUCTION: Wolfram syndrome (WFS) is a neurological and endocrinological degenerative disorder, also known as DIDMOAD (Diabetes Insipidus, early-onset Diabetes Mellitus, progressive Optic Atrophy, and Deafness) syndrome.
Cristina Ferreras, Vanessa Gorito, Jorge Pedro, Sofia Ferreira, Carla Costa, Rita Santos Silva, Cintia Castro Correia   +6 more
doaj   +1 more source

The challenge of pregnancy in the DIDMOAD syndrome

DIDMOAD syndrome includes diabetes insipidus, diabetes mellitus, optic atrophy and deafness. Pregnancies in the DIDMOAD syndrome are rare, and successful pregnancies are extremely rare. Despite the full DIDMOAD syndrome including diabetes mellitus for 30
Gallagher A, Hutchison RS, Kelly WF
core   +5 more sources