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Neurologic Clinics, 2010 Optic atrophy is a clinical term used to describe an optic disc thought to be paler than normal. Optic atrophy is not a diagnosis but an ophthalmoscopic sign. Evidence of visual loss (acuity, color vision, peripheral vision) should be present.
Karl C Golnik
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Trans-synaptic degeneration of the optic radiation from optic nerve atrophy [PDF]
Radiology Case Reports, 2021 Fourty-seven-year-old woman with 5-year history of progressive decreased left eye vision. Optical coherence tomography showed optic nerve atrophy (left > right) and brain MRI revealed T2 hyperintense signal along the course of left optic radiations.
Shingo Kihira, MD +4 more
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Orphanet Journal of Rare Diseases, 2012 Definition of the disease Dominant Optic Atrophy (DOA) is a neuro-ophthalmic condition characterized by a bilateral degeneration of the optic nerves, causing insidious visual loss, typically starting during the first decade of life.
Lenaers Guy +7 more
doaj +5 more sources
Türk Oftalmoloji Dergisi, 2011 Pur po se: To evaluate the relationship between peripapillary atrophy and optic disc parameters measured by Heidelberg Retina Tomography (HRT) and visual field findings in eyes with primary open-angle glaucoma.
Tamer Takmaz +3 more
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European Journal of Radiology Open, 2017 Background and purpose: Evaluating chronic sequelae of optic neuritis, such as optic neuropathy with or without optic nerve atrophy, can be challenging on whole brain MRI.
Veena R Iyer +2 more
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An unusual cause of optic atrophy in a child
Indian Journal of Ophthalmology, 2014 A 13-year-old child presenting with gross visual impairment was diagnosed as a case of optic atrophy. However, radiological investigations revealed osteopetrosis, which, though rare, can result in optic atrophy.
Nishant Kumar +4 more
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MRI of the intraorbital optic nerve in patients with autosomal dominant optic atrophy
Neuroradiology, 2000 Measurements of the intraorbital optic nerve were made using high-resolution coronal MRI in 10 adults with autosomal dominant optic atrophy. Comparisons were made with previous studies of 10 normal adult subjects.
Marcela Votruba +2 more
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Mutation of CRYAB encoding a conserved mitochondrial chaperone and antiapoptotic protein causes hereditary optic atrophy [PDF]
JCI InsightThe degeneration of retinal ganglion cells (RGC) due to mitochondrial dysfunctions manifests optic neuropathy. However, the molecular components of RGC linked to optic neuropathy manifestations remain largely unknown.
Chenghui Wang +11 more
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Asian Journal of Medical Sciences, 2023 Background: Optic atrophy is a clinical presentation in which the optic disc appears pale due to irreversible damage of retinal ganglion cells and axons in the anterior visual pathway.
Kabindra Bajracharya +4 more
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