Results 21 to 30 of about 7,304 (263)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Advances in Mechanical Engineering, 2014 The complex motorcycle wheel components of AM50A magnesium alloy had been formed by double control forming and die casting, respectively. The surface quality of components formed by double control forming was much better than die casting parts.
Jufu Jiang, Xi Nie, Ying Wang, Jing Yang
doaj +1 more source
Temperature Conditions Change in the High Pressure Die Casting mold Volume Depending on the Gating System Volume [PDF]
Archives of Foundry EngineeringThe high pressure die casting technology is characterized by high efficiency, which is given by pressing the liquid metal into the die cavity and the subsequent solidification of the cast in a short period of time.
J. Majernik +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Mechanism of die soldering during aluminum die casting [PDF]
China Foundry, 2015 Soldering is a unique casting defect associated with die casting or metal mold casting of aluminum alloys. It occurs when molten aluminum sticks or solders the surface of the die steel and remains there after the ejection of the casting, causing a ...
Qing-you Han
doaj
Exploring the concept of castability in magnesium die-casting alloys
Journal of Magnesium and Alloys, 2021 This paper provides a summary of the recent work completed and history of the measure of manufacturability in the magnesium die-casting industry. The most popular die-casting alloys utilized in this industry are based on the Mg–Al system, including AZ91,
J.P. Weiler
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
Temperature change and stress distribution analysis of die surface in Al-alloy die casting process and experimental study on die heat check [PDF]
China Foundry, 2008 The temperature change of the die surface in practical aluminum alloy die casting process was analyzed,and a 2D model was formulated on the basis of a deep concave round cavity without sliding core to analyze the stress distributions along the die ...
Hu Xinping, Zhao Guoqun, Wu Bingyao
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source