Results 41 to 50 of about 1,252,753 (304)

Characterization of vascular dysregulation in meriones shawi after high-calorie diet feeding

Clinical and Experimental Hypertension, 2018
The present study was initiated to characterize vascular dysregulations (contraction and relaxation) associated with metabolic defects in Merions shawi, a rodent from the gerbillidae family, submitted to 12 weeks high-calorie diet.
Badiaa lyoussi, khadija Cherkaoui-Tangi, Nicole Morel, Maurice Wibo   +3 more
doaj   +1 more source

Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet

Antioxidants, 2023
Carnosine and anserine supplementation markedLy reduce diabetic nephropathy in rodents. The mode of nephroprotective action of both dipeptides in diabetes, via local protection or improved systemic glucose homeostasis, is uncertain.
Tilman Pfeffer, Charlotte Wetzel, Philip Kirschner, Maria Bartosova, Tanja Poth, Constantin Schwab, Gernot Poschet, Johanna Zemva, Ruben Bulkescher, Ivan Damgov, Christian Thiel, Sven F. Garbade, Kristina Klingbeil, Verena Peters, Claus Peter Schmitt   +14 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Efek hipoglikemik tepung komposit (ubi jalar ungu, jagung kuning, dan kacang tunggak) pada tikus diabetes induksi streptozotocin

Jurnal Gizi Klinik Indonesia, 2014
Background: The composite flour (50% sweet potato, 30% corn, and 20% cowpea) had proven that it could substitute 100% wheat flour for biscuit making.
Carolina Sisca Djunaidi, Dian Rachmawanti Affandi, Danar Praseptiangga   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

PENGARUH EKSTRAK PROTEIN KACANG KOMAK (Lablab purpureus (L.) Sweet) PADA KADAR GLUKOSA DAN PROFIL LIPIDA SERUM TIKUS DIABETES [Effect of Protein Extract of Hyacinth Bean (Lablab purpureus (L.) sweet) on Glucose and Lipid Profiles Serum In Diabetic Rats]

Jurnal Teknologi dan Industri Pangan, 2011
The objectives of this research were to evaluate the effect of Lablab protein extract in diet on blood glucose concentration and lipid profiles of alloxan-induced diabetic rats.
Arif Hartoyo1)*, Deddy Muchtadi1), Made Astawan1), Dahrulsyah1), Adi Winarto2)   +4 more
doaj   +2 more sources

Anti-diabetic effects of emodin involved in the activation of PPAR gamma on high-fat diet-fed and low dose of streptozotocin-induced diabetic mice [PDF]

, 2010
Rheum palmatum unit has been widely applied in the clinical treatment of diabetes mellitus It has been found that emodin as the major bioactive component of R palmatum L exhibits the competency to activate peroxisomal proliferator-activated receptor ...
Yan, Xue, Liu, Wenjun, Ding, WJ, Chinese Acad Sci, Grad Univ, Coll Life Sci, 19 A,Yu Quan Rd, Beijing 100049, Peoples R China, Jianfeng, Ding   +6 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

BALANCING THE DIABETIC DIET [PDF]

JAMA: The Journal of the American Medical Association, 1922
The present interest in properly balancing the diabetic diet, stimulated particularly by the researches of Shaffer, 1 Newburgh and Marsh, 2 Woodyatt, 3 Wilder 4 and others, has led to efforts to work out a simple method of determining the food proportions required by any diabetic patient.
openaire   +2 more sources

Diabetic retinopathy at diagnosis of type 2 diabetes in Scotland [PDF]

, 2012
The prevalence of retinopathy at first screening is lower than in previous UK studies, consistent with earlier diagnosis of diabetes. Most newly diagnosed type 2 diabetic patients in Scotland are screened within an acceptable interval and the prevalence ...
Lee, N, Colhoun, H.M., H. C. Looker, Colhoun, H. M., M. Black, Sattar, N, Olson, J.A., Morris, A D, Olson, J. A., Philip, Sam, J. A. Olson, S. H. Wild, Olson, J A, Black, M., S. O. Nyangoma, Leese, G P, Doig, J, H. M. Colhoun, Looker, H C, Doig, J., ?, ?, J. A. McKnight, Nyangoma, S. O., Lindsay, R. S., null null, Nyangoma, S O, Lindsay, R S, Colhoun, H M, McKnight, J A, Leese, G.P., Black, M, Wild, S H, D. Cromie, Sattar, N., Cromie, D., Wild, S.H., A. D. Morris, Scottish Diabetic Retinopathy Screening Collaborative, McKnight, J. A., Morris, A.D., Lindsay, R.S., Leese, G. P., Morris, Andrew, Lee, N., G. P. Leese, N. Sattar, N. Lee, Cromie, D, Wild, S. H.; id_orcid, Looker, H. C., R. S. Lindsay, McKnight, J.A., J. Doig, Nyangoma, S.O., Philip, S., S. Philip, Looker, H.C.   +56 more
core   +1 more source