Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto +5 more
wiley +1 more source
The Association of Diet and Lifestyle Factors With Quality of Life and Self-Rated Health in Older Adults: The Loma Linda Longevity Study. [PDF]
Sella LF +4 more
europepmc +1 more source
SiDT1 Defines Plant Architecture Reminiscent of Green Revolution in Foxtail Millet
SiDT1 encodes a GA3‐oxidase that creates a semi‐dwarf, lodging‐resistant architecture reminiscent of the rice Green Revolution. The resulting ideotype performs well under dense planting and provides a valuable genetic resource for high‐yield, mechanized foxtail millet production. ABSTRACT Foxtail millet (Setaria italica) is a drought‐tolerant C4 cereal
Jianzhen Lv +13 more
wiley +1 more source
Factors Associated with Dietary Behaviour During Pregnancy: An Insight from the <i>SaperePer</i> Cohort. [PDF]
El Sherbiny S +5 more
europepmc +1 more source
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang +16 more
wiley +1 more source
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen +12 more
wiley +1 more source
Reproducibility of a 69-Item School Children's Food Frequency Questionnaire (69-Item SCh-FFQ) and Diet Quality Scores Among Polish Children Aged 7-9 Years. [PDF]
Sobaś K +3 more
europepmc +1 more source
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang +7 more
wiley +1 more source
The Relationship Between Combined Lifestyle Behaviors and Mental Illness in Emerging Adults: A Narrative Review. [PDF]
Armstrong N, Ciorciari A, Woolf K.
europepmc +1 more source
CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source

